Results 131 to 140 of about 4,956,614 (325)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Electrochemical and Fluorescence MnO₂-Polymer Dot Electrode Sensor for Osteoarthritis-Based Peroxisomal β-Oxidation Knockout Model

Biosensors
A coenzyme A (CoA-SH)-responsive dual electrochemical and fluorescence-based sensor was designed utilizing an MnO2-immobilized-polymer-dot (MnO2@D-PD)-coated electrode for the sensitive detection of osteoarthritis (OA) in a peroxisomal β-oxidation ...
Akhmad Irhas Robby, Songling Jiang, Eun-Jung Jin, Sung Young Park   +3 more
doaj   +1 more source

Electric propulsion [PDF]

Electric propulsion (EP) is an attractive option for unmanned orbital transfer vehicles (OTV's). Vehicles with solar electric propulsion (SEP) could be used routinely to transport cargo between nodes in Earth, lunar, and Mars orbit.
Garrison, Philip W.
core   +1 more source

Effects of stress on the immune system of fish [PDF]

, 1994
The effects of stress on the immune system of various fish species including dab Limanda limanda, flounder Platichthys flesus, sea bass Dicentrarchus labrax and gobies Zosterisessor ophiocephalus, were investigated from laboratory and field experiments ...
Farley, S., Lemaire-Gony, S., Pulsford, A.L.   +2 more
core  

Production and optical properties of liquid scintillator for the JSNS$^{2}$ experiment

, 2019
The JSNS$^{2}$ (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) experiment will search for neutrino oscillations over a 24 m short baseline at J-PARC.
Choi, J. H., Furuta, H., Gwak, P. J., Hasegawa, S., Hino, Y., Jang, H. I., Jang, J. S., Jeon, H. K., Jeon, S. H., Joo, K. K., Ju, K. W., Jung, D., Kim, S. B., Kim, S. Y., Lee, D. H., Maruyama, T., Pac, M., Park, J. S., Park, Y. S., Rott, C., Suekane, F., Ujiie, R., Yu, I.   +22 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Contributions to predicting contaminant leaching from secondary materials used in roads [PDF]

, 2004
Slags, coal ashes, and other secondary materials can be used in road construction. Both traditional and secondary materials used in roads may contain contaminants that may leach and pollute the groundwater.
Apul, Defne S
core   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Bio-Based Renewable Additives for Anti-Icing Applications (Phase II) [PDF]

, 2019
The performance and impacts of several agro-based anti-icers along with a traditional chloride-based anti-icer (salt brine) were evaluated. A statistical design of experiments (central composite design) was employed for developing anti-icing liquids ...
Alnuaimi, Eisa, Avalos, Brandon, Ewing, Alexander Charlemagne, Havens, Eden Adele, Nazari, Mehdi Honarvar, Oh, Taekil, Okon, Deborah Ave, Shi, Xianming   +7 more
core