A Kinetic Model-Driven Techno-Economic Analysis of Plastic Pyrolysis: Linking Process Dynamics to Economic Viability. [PDF]
Zaker Hosseiny F, Shi R.
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Enhanced ASR Mitigation and Carbon Reduction Potential of Local Natural Pozzolans as Alternatives to Fly Ash in Cement-Based Systems. [PDF]
Yang L, Ma M, Jin Z, Du F.
europepmc +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Process optimization of adsorbent production from waste printed circuit board non-metallic fractions based on climate-change impact and cumulative energy demand. [PDF]
Saleem J, Moghal ZKB, McKay G.
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
From Waste to Value-Added Resource: A Strategic Review of Recycling and Regeneration Pathways for Fiber-Reinforced Polymer Waste. [PDF]
Liu Y, Fan Y, Wang L, Qi W.
europepmc +1 more source
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Swelling Mechanism of Rubber Sealing Materials in Methanol Transportation Pipelines. [PDF]
Jiang Z +6 more
europepmc +1 more source

