Results 81 to 90 of about 6,195,681 (305)

An eCertificate Program in Transportation Planning [PDF]

DTRT06-G-0044In this project, researchers developed a proposal to extend the delivery of the recently developedGraduate Certificate in Transportation Planning at Texas A&M University (TAMU) to a wider audience viadistance education (online or ...
Texas Transportation Institute. University Transportation Center for Mobility, Joh, Kenneth, Ndubisi, Forster   +2 more
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Based on the Integration of the Improved A* Algorithm with the Dynamic Window Approach for Multi-Robot Path Planning

Applied Sciences
With the escalating demand for automation in chemical laboratories, multi-robot systems are assuming an increasingly prominent role in chemical laboratories, particularly in the task of transporting reagents and experimental materials.
Yong Han, Changyong Li, Zhaohui An
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Other title: Overview of the Kansas Department of Transportation Other title: Kansas Department of Transportation Overview Other title: KDOT Overview

, 2011
application/pdf Title supplied by cataloger from Kansas Department of Transportation website. "February 3, 2011." Presentation to the Kansas Legislature, House Transportation Committee, by staff of the Kansas Department of Transportation.Presentation ...
Kansas. Department of Transportation.
core  

A Novel Optimization Method and Its Application for Hazardous Materials Vehicle Routing Problem Under Different Road Conditions

Mathematics
With the increasing demand for hazardous materials (hazmat) from enterprises, port chemical industrial parks face growing risks in hazardous material transportation.
Fangwei Zhang, Lu Ding, Jun Jiang, Fanyi Kong, Xiaoyu Liu   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Assessing Lithium-Ion Battery Safety Under Extreme Transport Conditions: A Comparative Study of Measured and Standardised Parameters

Energies
The safety of lithium-ion batteries during transportation is critically important. However, current standards exhibit limitations, as their environmental testing parameter thresholds fail to fully encompass actual transportation conditions.
Yihan Pan, Xingliang Liu, Jinzhong Wu, Haocheng Zhou, Lina Zhu   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source