Results 101 to 110 of about 3,625,661 (313)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

NEW WOOD FOAM-HEAT INSULATING MATERIAL OBTAINED THROUGH OAK WOOD-DELIGNIFICATION PROCESS

Nonconventional Technologies Review, 2023
A technique for manufacturing wood heat-insulating material for construction (known as wood delignification) without seriously affecting the cellulosic structure was inspired by the practices of the pulp and paper industry and adapted to the mentioned ...
Lucian Paunescu, Eniko Volceanov, Bogdan Valentin Paunescu   +2 more
doaj  

The Role of Adult Fiddler Crab Environmental Acoustic Cues and Chemical Cues in Stimulating Molting of Field-Caught Megalopae [PDF]

, 2017
In mid-Atlantic estuaries, three fiddler crab species, Uca pugilator, Uca pugnax and Uca minax co-occur, with their adults occupying different habitat types distinguished by salinity and sediment size.
Piniak, Wendy Dow, Reinsel, Kathleen A., Waddell, Emily E., Welch, James M.   +3 more
core   +1 more source

On the path to a new generation of cement-based composites through the use of lignocellulosic micro/nanofibers [PDF]

, 2019
Due to its high biocompatibility, bio-degradability, and low cost, cellulose finds application in disparate areas of research. Here we focus our attention on the potential applications of cellulose nanofiber in cement-basedmaterials for the building ...
Chamorro Trenado, Miquel Ángel, Claramunt Blanes, Josep, Delgado Aguilar, Marc, Llorens Sulivera, Joan, Mutjé Pujol, Pere, Pareta Marjaneda, Maria Mercè, Reixach, Rafel, Tarrés Farré, Joaquim Agustí   +7 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Chemical and spectroscopic analysis of olive mill waste water during a biological treatment [PDF]

, 2007
The treatment of olive mill waste water was studied on the laboratory scale. Physico–chemical analyses showed the final products had a mean pH of 5.4 without neutralisation and 5.7 when lime was added to the process.
Bailly, Jean-René, El Hajjouji, Houda, Hafidi, Mohamed, Merlina, Georges, Revel, Jean-Claude, Winterton, Peter   +5 more
core   +5 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Disk Galaxy Models Driven by Stochastic Self-Propagating Star Formation

, 2010
We present a model of chemical and spectrophotometric evolution of disk galaxies based on a stochastic self-propagating star formation scenario. The model incorporates galaxy formation through the process of accretion, chemical and photometric evolution ...
Mineikis, T., Vansevičius, V.
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A review on synthesis and characterization of commercially available natural fibers: Part-I

Journal of Natural Fibers, 2019
Environmental friendly products are getting much attention nowadays because of their availability in abundance and their usability in many engineering applications.
P. Madhu, M. R. Sanjay, P. Senthamaraikannan, S. Pradeep, S. S. Saravanakumar, B. Yogesha   +5 more
doaj   +1 more source