Results 171 to 180 of about 165,414 (272)

Evolutionarily Optimal Risk Aversion

Risk Analysis, Volume 46, Issue 5, May 2026.
ABSTRACT In an experimental choice situation, we identify risk‐acceptability thresholds and show how such thresholds are updated in response to benchmark information, a recurrent feature of health, safety, and environmental (HS&E) risk governance. We present a theoretical framework linking the observed behavior to an underlying evolutionary parameter ...
Chmura, Nguyen, Biermann
wiley   +1 more source

Reconceptualizing Gender Transitioning: Recognition, Flexibility, and Safety in Nonbinary Identity Journeys

Sociological Inquiry, Volume 96, Issue 2, Page 285-304, May 2026.
This article interrogates gender transitioning by centering nonbinary experiences, which challenge the binary‐driven narratives that dominate both medical and sociological frameworks of transition. Drawing on seven focus groups with 48 nonbinary participants across multiple countries, this study explores three interrelated forms of transition: social ...
S. M. Rodriguez
wiley   +1 more source

A Bifunctional Small Molecule Degrader of the Long Noncoding RNA MALAT1 Triplex

Chemistry – A European Journal, Volume 32, Issue 15, 22 April 2026.
Targeting disease‐linked RNAs with small molecules is often limited by the modest impact of binding RNA structure alone. Here, we present a first‐in‐class bifunctional molecule that degrades the oncogenic lncRNA MALAT‐1 by inducing proximity between the RNA and a cleaving warhead.
Christian A. T. Brega, Benjamin A. Craig, Sigitas Mikutis, Rupert S. J. Proctor, Yuliia Vyborna, Galway Ivey, Maria Eleftheriou, Kostas Tzelepis, Mo Yang, Shaifaly Parmar, Javier Bonet‐Aleta, John S. Schneekloth Jr., Gonçalo J. L. Bernardes   +12 more
wiley   +1 more source

From Mechanisms to Materials: Oximate Reactivity and Emerging Strategies for Organophosphate Detoxification

ChemPhysChem, Volume 27, Issue 7, 14 April 2026.
The development of effective strategies for the detoxification of organophosphorus (OP) nerve agents has evolved from the early mechanistic studies of François Terrier and collaborators, who first elucidated the exceptional nucleophilicity of α‐effect species such as oximes and hydroxamates, to the modern design of supramolecular and material‐based ...
Pedro Rodríguez‐Dafonte
wiley   +1 more source

Bridging Optical and Mechanical Metamaterial/Metasurface Realms Toward Integrated Meta‐Systems

Advanced Optical Materials, Volume 14, Issue 14, 10 April 2026.
This perspective describes the rise of metamaterials in the field of materials science, specifically with optical and mechanical functionality. Fundamentals of both optical and mechanical metamaterials are discussed with a review of state‐of‐the‐art metamaterial science.
Justin Brackenridge, Jaejun Lee, Vladimir V. Tsukruk   +2 more
wiley   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, Volume 13, Issue 19, 2 April 2026.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Impact of Secondary Prevention on Mortality in the Building Trades National Medical Screening Program: Effectiveness of Occupational High‐Risk Management

American Journal of Industrial Medicine, Volume 69, Issue 4, Page 241-253, April 2026.
ABSTRACT Background Since 1997 the Building Trades National Medical Screening Program (BTMed) has offered medical exams to construction workers employed in US nuclear weapons facilities. The process consists of two steps: (1) a detailed work history interview; and (2) a medical exam.
Knut Ringen, John M. Dement, Marianne Cloeren, Sammy Almashat, William Grier, Stella Hines, Laura S. Welch, Kim Cranford, Scott Haas, Patricia Quinn, Anna Chen, Miles Fisher   +11 more
wiley   +1 more source

Antiproliferative Effect of 24‐Deoxysericoside From Terminalia macroptera Guill. & Perr. (Combretaceae) Against Breast Carcinoma: In Vitro, Molecular Docking and ADME Assessment

Cancer Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background Terminalia macroptera (Combretaceae) is an important medicinal plant in the traditional pharmacopeia in most tropical areas, where its different parts are used in treating illnesses including cancer. Aims In this study, two oleanane‐type triterpenoids: terminolic acid (TM32) and arjungenin (TM34), together with three saponins ...
Romeo Toko Feunaing, Alfred Ngenge Tamfu, Abel Joel Yaya Gbaweng, Cyrille Leonel Tchuente Djoko, Emmanuel Talla, El Hassane Anouar, Stephane Zingue   +6 more
wiley   +1 more source

Toxicity and utilization of chemical weapons: does toxicity and venom utilization contribute to the formation of species communities? [PDF]

Ecol Evol, 2015
Westermann FL, McPherson IS, Jones TH, Milicich L, Lester PJ.   +4 more
europepmc   +1 more source

A Hybrid YOLO–SE Attention Based Deep Learning Framework for Robust Weapon Detection in Surveillance Imagery

Engineering Reports, Volume 8, Issue 4, April 2026.
This study presents a hybrid real‐time weapon detection system combining lightweight image classification (NASNetMobile) with precise object localization (YOLOv8n), optimizing performance and computational efficiency. The proposed pipeline enables scalable, accurate threat detection in surveillance systems, advancing security in resource‐constrained ...
Ashiful Nahar Bithi, Mridul Ghosh, Mrinal Kanti Saha Joy, Emtu Rani Paul, Md. Ferdous Bin Hafiz, Niaz Ashraf Khan, Shohag Barman, Md Mehedi Hasan, Hira Lal Gope, Md Masum Billah   +9 more
wiley   +1 more source