Results 1 to 10 of about 2,114,959 (246)

Theoretical prediction on the hydrolysis rate of the new types of nerve agents: A density functional study [PDF]

open access: yesToxicology Reports, 2023
Although the hydrolysis mechanism of the nerve agents, which is the main decontamination pathway, has been studied experimentally and theoretically, the reliable theoretical prediction method for the hydrolysis rate is not studied yet. Furthermore, after
Md Al Mamunur Rashid   +3 more
doaj   +3 more sources

A Thermophilic Bacterial Esterase for Scavenging Nerve Agents: A Kinetic, Biophysical and Structural Study [PDF]

open access: yesMolecules, 2021
Organophosphorous nerve agents (OPNA) pose an actual and major threat for both military and civilians alike, as an upsurge in their use has been observed in the recent years.
Janek Bzdrenga   +5 more
doaj   +3 more sources

Non-quaternary oximes detoxify nerve agents and reactivate nerve agent-inhibited human butyrylcholinesterase [PDF]

open access: yesCommunications Biology, 2021
Amitai et al. identified 4 potential small molecule antidotes toward nerve agents poisoning by high-throughput-screening of over 150,000 compounds. Unique non-quaternary oximes represent new potential antidotes for future development as they detoxified ...
Gabriel Amitai   +10 more
doaj   +3 more sources

Efficient Detection of Nerve Agents through Carbon Nitride Quantum Dots: A DFT Approach [PDF]

open access: yesNanomaterials, 2023
V-series nerve agents are very lethal to health and cause the inactivation of acetylcholinesterase which leads to neuromuscular paralysis and, finally, death. Therefore, rapid detection and elimination of V-series nerve agents are very important. Herein,
Yasair S. S. Al-Faiyz   +7 more
doaj   +2 more sources

Classification, Chemical, and Toxicological Properties of Carbamate Nerve Agents [PDF]

open access: yesJournal of Xenobiotics
Nerve agents are usually identified as exceedingly toxic organophosphate compounds like VX and sarin. Nevertheless, although carbamate nerve agents (CNAs) have been developed they constitute the least studied class of nerve agents outside military ...
Georgios Pampalakis
doaj   +2 more sources

A clinical approach to an unidentified aerosolized bioterrorism agent: a narrative review for emergency providers [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2023
The current heightened international political climate is accompanied by increased risk of chemical or biological agent weaponization. Historical accounts of biochemical warfare are extensive, and considering the recent use of such agents for targeted ...
Rashed Alremeithi   +4 more
doaj   +1 more source

Nerve agents: A guide for emergency nurses. Part 1 [PDF]

open access: yes, 2020
Recent incidents in the UK and the alleged chemical attacks in Syria by the Bashar al-Assad regime have brought the subject of chemical weapons back into the public domain. To date these types of event have been relatively rare because terrorist plans to
McGhee, Stephen   +2 more
core   +2 more sources

Detection of a Nerve Agent Simulant by a Fluorescent Sensor Array

open access: yesChemosensors, 2023
Detection of nerve agents (NAs) gas in the environment through portable devices to protect people in case of emergencies still remains a challenge for scientists involved in this research field. Current detection strategies require the use of cumbersome,
Rossella Santonocito   +5 more
doaj   +1 more source

Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically available compounds lack a broad ...
Daniel A. S. Kitagawa   +14 more
doaj   +1 more source

Chemical warfare agents

open access: yesJournal of Pharmacy and Bioallied Sciences, 2010
Among the Weapons of Mass Destruction, chemical warfare (CW) is probably one of the most brutal created by mankind in comparison with biological and nuclear warfare.
K Ganesan, S K Raza, R Vijayaraghavan
doaj   +1 more source

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