Results 1 to 10 of about 1,816,017 (199)

A clinical approach to an unidentified aerosolized bioterrorism agent: a narrative review for emergency providers [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2023
The current heightened international political climate is accompanied by increased risk of chemical or biological agent weaponization. Historical accounts of biochemical warfare are extensive, and considering the recent use of such agents for targeted ...
Rashed Alremeithi   +4 more
doaj   +1 more source

Detection of a Nerve Agent Simulant by a Fluorescent Sensor Array

open access: yesChemosensors, 2023
Detection of nerve agents (NAs) gas in the environment through portable devices to protect people in case of emergencies still remains a challenge for scientists involved in this research field. Current detection strategies require the use of cumbersome,
Rossella Santonocito   +5 more
doaj   +1 more source

Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically available compounds lack a broad ...
Daniel A. S. Kitagawa   +14 more
doaj   +1 more source

An organized 3D in vitro model for peripheral nerve studies [PDF]

open access: yes, 2013
Three-dimensional cell cultures have been proposed to address the limitations in two-dimensional cell cultures (i.e. lack of relevant architectural features) and very few have developed 3D cell culture methods for peripheral nerve studies. Therefore, the
Daud, Muhammad Fauzi
core   +6 more sources

Nerve agents: A guide for emergency nurses. Part 1 [PDF]

open access: yes, 2020
Recent incidents in the UK and the alleged chemical attacks in Syria by the Bashar al-Assad regime have brought the subject of chemical weapons back into the public domain. To date these types of event have been relatively rare because terrorist plans to
McGhee, Stephen   +2 more
core   +1 more source

A Thermophilic Bacterial Esterase for Scavenging Nerve Agents: A Kinetic, Biophysical and Structural Study

open access: yesMolecules, 2021
Organophosphorous nerve agents (OPNA) pose an actual and major threat for both military and civilians alike, as an upsurge in their use has been observed in the recent years.
Janek Bzdrenga   +5 more
doaj   +1 more source

Characterization of the Interaction of Nerve Agent Mimics with Selected Synthetic Receptors

open access: yesOrganic Materials, 2022
Qualitative NMR spectroscopic and quantitative calorimetric binding studies were performed to characterize the interaction of nontoxic mimics of the V-type nerve agent VX (O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate) and the Novichok ...
Carolina Braga Barbosa   +3 more
doaj   +1 more source

Chemical warfare agents

open access: yesJournal of Pharmacy and Bioallied Sciences, 2010
Among the Weapons of Mass Destruction, chemical warfare (CW) is probably one of the most brutal created by mankind in comparison with biological and nuclear warfare.
K Ganesan, S K Raza, R Vijayaraghavan
doaj   +1 more source

Utilizing Zirconium MOF‐functionalized Fiber Substrates Prepared by Molecular Layer Deposition for Toxic Gas Capture and Chemical Warfare Agent Degradation

open access: yesGlobal Challenges, 2021
Metal–organic frameworks (MOFs) are a class of porous organic‐inorganic solids extensively explored for numerous applications owing to their catalytic activity and high surface area.
Agnieszka Gorzkowska‐Sobas   +6 more
doaj   +1 more source

Fluorescence Spectroscopy Approaches for the Development of a Real-Time Organophosphate Detection System Using an Enzymatic Sensor

open access: yesSensors, 2015
Organophosphates are organic substances that contain a phosphoryl or a thiophosphoryl bond. They are mainly used around the world as pesticides, but can also be used as chemical warfare agents. Their detection is normally entrusted to techniques like GC-
Paola Carullo   +4 more
doaj   +1 more source

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