Results 41 to 50 of about 2,114,959 (246)
Exploiting macrocyclic polylactam for sensing V-series nerve agents: A computational study
Results in ChemistryThe nerve agents are organophosphorus compounds (OPs) developed as chemical warfare agents (CWAs) that inhibit acetylcholinesterase (AChE) and lead to impeding neurological signals in mammals.
Dipankar Das, Bishwajit Ganguly
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Investigating possibilities and recent trends for the development of novel decontamination technologies [PDF]
Scientific Technical ReviewDespite international prohibition of chemical warfare agents (CWAs), defined in Chemical Weapons Convention, recent events during military conflict in Syria and isolated events in Salisbury (UK) and Kuala Lumpur (Malesya) airport prove that these agents ...
Vitorović-Todorović Maja D. +1 more
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Chemical Weapons: History of the Study of Organophosphorus Toxic Agents Abroad
Вестник войск РХБ защиты, 2023 Organophosphorus compounds occupy a unique positon among all chemical warfare agents (CWA's). Since the 1930-s their high toxicity, wide range of physical-chemical properties and complex action attracted close attention of foreign military experts.
I. A. Nelga +5 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
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Orbital: The Electronic Journal of Chemistry, 2008 The chemistry of the phosphorus-oxygen bond is widely used in biological systems in many processes, such as energy transduction and the storage, transmission and expression of genetic information, which are essential to living beings in relation to a ...
Luciano Albino Giusti +1 more
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Cumhuriyet Science Journal, 2020 In this study, a carboxymethyldextran chip based sensor system is developed that selectively recognizes and binds nerve agent molecules used in chemical weapons. Nerve agents fall under the group of organophosphorus compounds and irreversibly inhibit the
Ozan Yağmuroğlu, Sibel Emir Diltemiz
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Nerve cell differentiation in hydra requires two signals [PDF]
, 1986 Endogenous signals controlling nerve cell commitment in hydra were investigated using an assay for committed nerve precursors. Extracts of hydra tissue were prepared and tested for their ability to induce nerve cell commitment.
Schaller, Chica H. +2 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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, 2023 Nerve agents are highly toxic compounds that have been used as chemical warfare agents (CWAs) in recent years. Therefore development of protective measures against these compounds remains relevant.
Koning, M.C. de +4 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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