Results 21 to 30 of about 219,191 (253)
Chemical warfare agents: Structure, properties, decontamination (part 1)
Журнал органічної та фармацевтичної хіміїThe review is aimed at summarizing and systematizing information on various methods of deactivation of chemical warfare agents required on the battlefield, in laboratories, research institutions, production facilities, as well as information on storage ...
Alexander E. Shumeiko +1 more
doaj +1 more source
Acetylcholinesterase: The “Hub” for Neurodegenerative Diseases and Chemical Weapons Convention
Biomolecules, 2020 This article describes acetylcholinesterase (AChE), an enzyme involved in parasympathetic neurotransmission, its activity, and how its inhibition can be pharmacologically useful for treating dementia, caused by Alzheimer’s disease, or as a warfare ...
Samir F. de A. Cavalcante +7 more
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Esters of organophosphorus acids: Toxicity, application and removal from the environment [PDF]
Scientific Technical Review, 2019 Esters of organophosphorus acids (OPs) are widely used nowadays. They have an application as pesticides, drugs or chemical warfare agents. Their acute toxicity is ascribed to the inhibition of acetylcholinesterase (AChE), a key enzyme in the transmission
Anićijević Vladan J. +3 more
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Preparation and Chemical Protective Clothing Application of PVDF Based Sodium Sulfonate Membrane
Membranes, 2020 Chemical protective clothing (CPC) is major equipment to protect human skin from hazardous chemical warfare agents (CWAs), especially nerve agents and blister agents. CPC performance is mainly dominated by the chemical protective material, which needs to
Yue Zhao +10 more
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Química NovaStraightforward, microscale, Ellman's cholinesterase test procedures are presented, useful for screening of novel compounds aiming at neurodegenerative diseases and antidotes towards nerve agents and pesticides.
Samir F. de A. Cavalcante +6 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan +1 more
wiley +1 more source
Sensors, 2009 A cholinesterase based biosensor was constructed in order to assess the effects of ionizing radiation on exposed AChE. Although the primary objective of the experiment was to investigate the effect of ionizing radiation on the activity of the biosensor ...
Miroslav Pohanka, Miroslav Koch
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Toxics, 2022 The therapeutic efficacy of treatments for acute intoxication with highly toxic organophosphorus compounds, called nerve agents, usually involves determination of LD50 values 24 h after nerve agent challenge without and with a single administration of ...
Jiri Kassa +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot +6 more
wiley +1 more source
Interactions of cyclodextrins and their derivatives with toxic organophosphorus compounds
Beilstein Journal of Organic Chemistry, 2016 The aim of this review is to provide an update on the current use of cyclodextrins against organophosphorus compound intoxications. Organophosphorus pesticides and nerve agents play a determinant role in the inhibition of cholinesterases.
Sophie Letort +4 more
doaj +1 more source