Results 21 to 30 of about 4,888,974 (334)

Nerve Agents

Schaffer DH, Hayoun MA.
europepmc   +3 more sources

Near-instantaneous catalytic hydrolysis of organophosphorus nerve agents with zirconium-based MOF/hydrogel composites

Chem Catalysis, 2021
Summary Zirconium-based metal-organic frameworks (Zr-MOFs) with Lewis-acidic sites are potent catalysts for degrading organophosphorus nerve agents.
Kaikai Ma, Megan C. Wasson, Xingjie Wang, Xuan Zhang, Karam B. Idrees, Zhijie Chen, Yufang Wu, Seung Joon Lee, Ran Cao, Yongwei Chen, Lifeng Yang, Florencia A. Son, Timur Islamoglu, G. Peterson, J. Mahle, O. Farha   +15 more
semanticscholar   +1 more source

Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically available compounds lack a broad ...
Daniel A. S. Kitagawa, Rafael B. Rodrigues, Thiago N. Silva, Wellington V. dos Santos, Vinicius C. V. da Rocha, Joyce S. F. D. de Almeida, Leandro B. Bernardo, Taynara Carvalho-Silva, Cintia N. Ferreira, Angelo A. T. da Silva, Alessandro B. C. Simas, Eugenie Nepovimova, Kamil Kuča, Tanos C. C. França, Samir F. de A. Cavalcante   +14 more
doaj   +1 more source

Nerve agents: emergency preparedness [PDF]

BMJ Military Health, 2020
Nerve agents (NAs) are a highly toxic group of chemical warfare agents. NAs are organophosphorus esters with varying physical and chemical properties depending on the individual agent. The most recently developed class of NA is‘Novichok’, the existence of which was first revealed in the early 1990s, just before Russia signed the Chemical Weapons ...
Alan George Andrew Weir, S Makin, J Breeze   +2 more
openaire   +2 more sources

Continuous Opioid Monitoring along with Nerve Agents on a Wearable Microneedle Sensor Array.

Journal of the American Chemical Society, 2020
There are urgent needs for sensing devices capable of distin-guishing between episodes of opioid overdose and nerve agent poisoning. This work presents a wearable microneedle sensor array for minimally-invasive continuous electrochemical detection of ...
R. Mishra, Y. G. Kotagiri, Zhanhong Li, Chochanon Moonla, Mona A. Mohamed, Farshad Tehrani, H. Teymourian, Joseph Wang   +7 more
semanticscholar   +1 more source

Chemical warfare agents

Journal of Pharmacy and Bioallied Sciences, 2010
Among the Weapons of Mass Destruction, chemical warfare (CW) is probably one of the most brutal created by mankind in comparison with biological and nuclear warfare.
K Ganesan, S K Raza, R Vijayaraghavan
doaj   +1 more source

Long-term vascular access ports as a means of sedative administration in a rodent fMRI survival model [PDF]

, 2011
The purpose of this study is to develop a rodent functional magnetic resonance imaging (fMRI) survival model with the use of heparin-coated vascular access devices.
Cho, Younghoon R, Hettinger, Patrick C, Hyde, James S, Li, Rupeng, Matloub, Hani S, Pawela, Christopher P, Rowe, Daniel B., Yan, Ji-Geng   +7 more
core   +2 more sources

Fluorescence Spectroscopy Approaches for the Development of a Real-Time Organophosphate Detection System Using an Enzymatic Sensor

Sensors, 2015
Organophosphates are organic substances that contain a phosphoryl or a thiophosphoryl bond. They are mainly used around the world as pesticides, but can also be used as chemical warfare agents. Their detection is normally entrusted to techniques like GC-
Paola Carullo, Giovanni Paolo Cetrangolo, Luigi Mandrich, Giuseppe Manco, Ferdinando Febbraio   +4 more
doaj   +1 more source

Characterization of the Interaction of Nerve Agent Mimics with Selected Synthetic Receptors

Organic Materials, 2022
Qualitative NMR spectroscopic and quantitative calorimetric binding studies were performed to characterize the interaction of nontoxic mimics of the V-type nerve agent VX (O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate) and the Novichok ...
Carolina Braga Barbosa, Patrick Gaß, Daniel J. Hamsch, Stefan Kubik   +3 more
doaj   +1 more source

Neurotoxicity [PDF]

, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust, Creeley, Feldman, Grandjean, Herken, Panzica, Parent, Pessah, Rice, Román, Spencer, Spencer, Tu, Vinken, Yasui, Zawia   +15 more
core   +2 more sources