A Thermophilic Bacterial Esterase for Scavenging Nerve Agents: A Kinetic, Biophysical and Structural Study [PDF]
Molecules, 2021 Organophosphorous nerve agents (OPNA) pose an actual and major threat for both military and civilians alike, as an upsurge in their use has been observed in the recent years.
Janek Bzdrenga +5 more
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Hydrolysis and enzymatic degradation of Novichok nerve agents. [PDF]
Heliyon, 2020 Several parameters of the Novichok nerve agents A230, A232 and A234 were determined. Hydrolysis rates were approximately one to three orders of magnitude slower than G-type nerve agents and approximately zero to two orders of magnitude slower than V-type
Harvey SP, McMahon LR, Berg FJ.
europepmc +2 more sources
Classification, Chemical, and Toxicological Properties of Carbamate Nerve Agents [PDF]
Journal of XenobioticsNerve agents are usually identified as exceedingly toxic organophosphate compounds like VX and sarin. Nevertheless, although carbamate nerve agents (CNAs) have been developed they constitute the least studied class of nerve agents outside military ...
Georgios Pampalakis
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Acute and long-term consequences of exposure to organophosphate nerve agents in humans. [PDF]
Epilepsia, 2018 Nerve agents are organophosphate (OP) compounds and among the most powerful poisons known to man. A terrorist attack on civilian or military populations causing mass casualties is a real threat. The OP nerve agents include soman, sarin, cyclosarin, tabun,
Figueiredo TH +3 more
europepmc +2 more sources
Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents. [PDF]
J Pharmacol Exp Ther, 2018 Organophosphates (OP) such as the pesticide diisopropylfluorophosphate (DFP) and the nerve agent sarin are lethal chemicals that induce seizures, status epilepticus (SE), and brain damage.
Wu X, Kuruba R, Reddy DS.
europepmc +2 more sources
3D Fractals as SERS Active Platforms: Preparation and Evaluation for Gas Phase Detection of G-Nerve Agents [PDF]
Micromachines, 2018 One of the main limitations of the technique surface-enhanced Raman scattering (SERS) for chemical detection relies on the homogeneity, reproducibility and reusability of the substrates.
Marta Lafuente +5 more
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Toxic chemical weapons of assassination and warfare: nerve agents VX and sarin. [PDF]
Toxicol Commun, 2017 The use of VX and sarin as weapons of assassination and warfare raises important considerations for healthcare professionals who may encounter victims, bystanders, and responders who require prompt assessment and treatment.
Chai PR +3 more
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After Salisbury Nerve Agents Revisited
Molecular Informatics, 2018 In March 2018 the term Novichok (Hoвичoκ) became publically known following an attempted murder of a former Russian spy in Salisbury, UK. Novichok is the name of a group of nerve agents secretly produced by Russia in the later stages of the Cold War ...
L. Carlsen
semanticscholar +3 more sources
A clinical approach to an unidentified aerosolized bioterrorism agent: a narrative review for emergency providers [PDF]
Clinical and Experimental Emergency Medicine, 2023 The current heightened international political climate is accompanied by increased risk of chemical or biological agent weaponization. Historical accounts of biochemical warfare are extensive, and considering the recent use of such agents for targeted ...
Rashed Alremeithi +4 more
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Detection of a Nerve Agent Simulant by a Fluorescent Sensor Array
Chemosensors, 2023 Detection of nerve agents (NAs) gas in the environment through portable devices to protect people in case of emergencies still remains a challenge for scientists involved in this research field. Current detection strategies require the use of cumbersome,
Rossella Santonocito +5 more
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