Results 111 to 120 of about 39,906 (300)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Discovery of an Extremely r-process-enhanced Thin-disk Star with [Eu/H] = +0.78

The Astrophysical Journal Letters
Highly r -process-enhanced (RPE) stars are rare and usually metal poor ([Fe/H] < −1.0), and they mainly populate the Milky Way halo and dwarf galaxies. This study presents the discovery of a relatively bright ( V = 12.72), highly RPE ( r -II) star ([Eu ...
Xiao-Jin Xie, Jianrong Shi, Hong-Liang Yan, Tian-Yi Chen, Carlos Allende Prieto, Timothy C. Beers, Shuai Liu, Chun-Qian Li, Ming-Yi Ding, Yao-Jia Tang, Ruizhi Zhang, Renjing Xie   +11 more
doaj   +1 more source

HST spectroscopy of chemically peculiar hot subdwarfs: PG 0909+276 and UVO0512–08

Open Astronomy, 2017
High-resolution ultraviolet spectroscopy of two chemically peculiar hot subdwarfs, PG 0909+276 and UVO0512-08, has been obtained using the Hubble Space Telescope.
Wild James, Jeffery Christopher Simon
doaj   +1 more source

Model atmospheres of chemically peculiar stars: Self-consistent empirical stratified model of HD24712

, 2009
High-resolution spectra of some chemically peculiar stars clearly demonstrate the presence of strong abundance gradients in their atmospheres. However, these inhomogeneities are usually ignored in the standard scheme of model atmosphere calculations ...
Alecian, Babel, Bard, Bard, Black, Blackwell, Blackwell, Blanco, Campos, D. Shulyak, Fleurier, Garz, Goncharsky, Hauck, Hauschildt, Hui-Bon-Hoa, Khan, Khan, Kochukhov, Kochukhov, Kochukhov, Kochukhov, Kochukhov, Kupka, L. Mashonkina, Lueftinger, Lundberg, Mashonkina, Mashonkina, Mashonkina, Mashonkina, Michaud, Nieuwenhuijzen, O. Kochukhov, Piskunov, Piskunov, Piskunov, Raassen, Ryabchikova, Ryabchikova, Ryabchikova, Ryabchikova, Rybicki, Rybicki, Seaton, Smith, Smith, Smith, Smith, Stepanov, T. Ryabchikova, Vogt, Warner, Weiss, Wolff   +54 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

A search for peculiar stars in the open cluster Hogg 16

, 2017
The study of chemically peculiar (CP) stars in open clusters provides valuable information about their evolutionary status. Their detection can be performed using the $\Delta a$ photometric system, which maps a characteristic flux depression at $\lambda \
Aidelman, Yael J., Azatyan, Naira M., Cariddi, Stefano, Kurfürst, Petr, Netopil, Martin, Paunzen, Ernst, Pintado, Olga I., Štofanová, Lýdia   +7 more
core   +1 more source

X-ray emission from chemically peculiar stars

The Astrophysical Journal, 1994
We have searched the Roentgen Satellite (ROSAT) All-Sky Survey (RASS) database at the positions of about 100 magnetic Bp-Ap stars of the helium-strong, helium-weak, silicon, and strontium-chromium subclasses. We detect X-ray sources at the positions of 10 of these stars; in four cases the X-ray emission presumably arises from an early-type companion ...
S. A. Drake, J. L. Linsky, J. H. M. M. Schmitt, C. Rosso   +3 more
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

An Unsupervised Machine Learning Approach to Identify Spectral Energy Distribution Outliers: Application to the S-PLUS DR4 Data

The Astronomical Journal
Identification of specific stellar populations using photometry for spectroscopic follow-up is a first step to confirm and better understand their nature.
F. Quispe-Huaynasi, F. Roig, N. Holanda, V. Loaiza-Tacuri, Romualdo Eleutério, C. B. Pereira, S. Daflon, V. M. Placco, R. Lopes de Oliveira, F. Sestito, P. K. Humire, M. Borges Fernandes, A. Kanaan, C. Mendes de Oliveira, T. Ribeiro, W. Schoenell   +15 more
doaj   +1 more source