Results 111 to 120 of about 56,211 (225)

Early Functional Impairment in Smokers with CT-Detected Emphysema: Spirometry Provides Complementary Physiological Information in Lung Cancer Screening. [PDF]

Biomedicines
Dimic-Janjic S, Buha I, Cvejic J, Kostadinovic N, Stamenic S, Postic A, Ratkovic A, Stosic-Markovic K, Sekulovic-Radovanovic I, Vukoja M, Trboljevac N, Isovic L, Stevic R, Colic N, Lukic K, Popevic S, Djurdjevic N, Savic M, Subotic N, Stjepanovic M.   +19 more
europepmc   +1 more source

Titanium‐Catalyzed Diastereoselective Keto‐ and Iminonitrile Cyclizations

Chemistry – A European Journal, EarlyView.
The titanium(III)‐catalyzed diastereoselective cyclization of readily‐available substituted ketonitriles gives cyclopentanones in good yield and stereoselectivity. Subsequent 1,2‐addition allows the preparation of cyclopentyls with three consecutive stereocenters.
Christoph Kern, Ritu Singh, Michael A. Unkrig‐Bau, Lukas Jakob, Jan Streuff   +4 more
wiley   +1 more source

Oxidative Generation and Reactivity of the Cyclopropyl Radical From a Martin Silicate

Chemistry – A European Journal, EarlyView.
A photoredox strategy employing Martin silicates enables the oxidative generation and controlled capture of cyclopropyl radicals, including the naked one, long considered challenging intermediates. The method affords functionalized cyclopropanes through both Giese‐type additions and dual nickel/photoredox C(sp3)−C(sp2) cross‐couplings.
Amal Lakhal, Alexandre Millanvois, Louis Fensterbank, Cyril Ollivier   +3 more
wiley   +1 more source

Consequences of Medium-Pore Zeolite Constraints for Alkene Cracking-The Case of n-Pentene. [PDF]

Angew Chem Int Ed Engl
Zhao R, Schallmoser S, Haller GL, Sanchez-Sanchez M, Lercher JA.   +4 more
europepmc   +1 more source

Synthesis of the Phospha‐Wittig Reagent Me3P = P(C2F5) and Generation of a Phospanyl‐Wittig Derivative Me3P = C(CF3)P(C2F5)F

Chemistry – A European Journal, EarlyView.
The first example of a simple alkylated phosphinidene‐adduct (“phospha‐Wittig”) is reported. The synthesis of Me3PPC2F5 was enabled through reaction of the cyclotetraphosphane (PC2F5)4 with PMe3. The phosphanyl‐functionalized Wittig reagent Me3PC(CF3)P(C2F5)F was prepared by treating the diphosphane P2(C2F5)4 with PMe3.
Lukas Hartmann, Hannah Koch, Julia Bader, Beate Neumann, Jan‐Hendrik Lamm, Hans‐Georg Stammler, Mira Kessler, Berthold Hoge   +7 more
wiley   +1 more source

Direct access to 2-imidazolines from unactivated alkenes. [PDF]

Chem Sci
Schiele S, Paschke AK, Romiti G, Morandi B.   +3 more
europepmc   +1 more source

Germylium Catalyzed Dehydrofluorination Reactions of Fluorinated Alkanes

Chemistry – A European Journal, EarlyView.
Dehydrofluorination reactions of fluorinated alkanes catalyzed by germylium ions are reported. Computational studies of the mechanism revealed an E2 type mechanism involving a germane as a base to facilitate olefin formation in competition with an SN2 mechanism for hydrodefluorination.
Julie Borel, Morten Lehmann, Martin Kaupp, Thomas Braun   +3 more
wiley   +1 more source

N─H or O─H Bond Activation With a Bicyclic Si4 Ring Compound

Chemistry – A European Journal, EarlyView.
The bicyclic Si4 ring compound with zwitterionic character reacts with NH3, H2O, and selected alcohols to give functionalized saturated silicon rings, siliconoid clusters with unsubstituted Si atoms, or simple 1,3‐addition products. The experimentally observed reactivity could be rationalized based on results from mechanistic calculations employing ...
Michael Quest, Florian Schreiner, Alexander Hepp, Constantin G. Daniliuc, Kasperi M. Salonen, Janne Körkkö, Heikki M. Tuononen, Felicitas Lips   +7 more
wiley   +1 more source

Mild C─F Activation of Azido(per)Fluoroalkanes

Chemistry – A European Journal, EarlyView.
Mild and selective activation of C(sp3)–F bonds in azido(per)fluoroalkanes using thiolates was developed, leading to novel functionalized azides. The reaction is initiated by nucleophilic attack of the sulfur atom to the terminal nitrogen of the azido group, followed by fluoride ion elimination.
Olena Shaitanova, María Martínez Mallo, Sergii Suikov, Blanka Klepetářová, Josef Filgas, Petr Slavíček, Lucie Bednárová, Petr Beier   +7 more
wiley   +1 more source

Correction: Discovery of fully synthetic FKBP12-mTOR molecular glues. [PDF]

Chem Sci
Deutscher RCE, Meyners C, Repity ML, Sugiarto WO, Kolos JM, Maciel EVS, Heymann T, Geiger TM, Knapp S, Lermyte F, Hausch F.   +10 more
europepmc   +1 more source