Results 151 to 160 of about 423,426 (288)

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Acridinium Chemiluminogenic Labels-Synthesis, Analytical Performance, and Mechanism of Light Generation-A Comparison in View of Biomedical Diagnostics. [PDF]

Molecules
Krzymiński K, Zadykowicz B, Czechowska J, Rudnicki-Velasquez P, Serdiuk I, Sieradzan AK, Holec-Gąsior L.   +6 more
europepmc   +1 more source

Infrared emission from desorbed NO2(*) and NO(*) [PDF]

Infrared photons from the radiative cascade accompany both the gas phase NO2 continuum chemiluminescence (which originates from its 2B2 and 2B1 states) and the NO beta bands.
Barrett, J. L., Kofsky, I. L.
core   +1 more source

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

Available Evidence on the Diagnostic Accuracy of Chemiluminescence for Detecting Dysplasia or Malignant Transformation in Oral Potentially Malignant Disorders (OPMDs): A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Esperouz F, Lorusso M, Troiano G, Zhurakivska K, Ciavarella D, Lo Muzio L, Lo Russo L.   +6 more
europepmc   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Prussian blue-supported platinum nanoparticles as pH-Universal catalase mimics: enabling robust chemiluminescent immunoassay for VEGF in clinical diagnostics. [PDF]

Front Bioeng Biotechnol
Yang Y, Li J, Hu X, Xiu Y, Zhang M, Wang C, Liu X, Liang B, Xing D, Zhang T.   +9 more
europepmc   +1 more source

Upper atmosphere chemical release study Final report [PDF]

Chemical release experiments to study upper atmosphere including night sky oxygen ...
Brown, H. K., Padur, J., Pressman, J., Rosen, C., Sharma, A.   +4 more
core   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Radical Electroprecipitation from a Water|Oil|Electrode Interface Prolongs "Electro"Chemiluminescence of the Tris(2,2'-bipyridyl)Ruthenium(II) and Benzoyl Peroxide System by 10³. [PDF]

Angew Chem Int Ed Engl
Carrel DM, Layman BR, Hill ML, Dick JE.
europepmc   +1 more source