Sensitive superoxide detection in vascular cells by the new chemiluminescence dye L-012 [PDF]
The detection superoxide production in vascular cells is usually limited by a low sensitivity of available assays, We tested the applicability of the luminol derivate L-012 {[}8-amino-5-chloro-7-phenylpyridol{[}3,4-d]pyridazine-l,4(2H,3H)dione] to ...
Gloe, Torsten +4 more
core +1 more source
Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease [PDF]
Previous studies showed that YAP1 is over-expressed in hepatocellular carcinoma (HCC). Here we observed higher expression of Yap1/Ctgf axis in dysplastic nodules and HCC chemically-induced in F344 rats, genetically susceptible to hepatocarcinogenesis ...
Avila, Matias A. +13 more
core +2 more sources
The third-stage larvae (L3) of Anisakis simplex are the most important source of hidden allergens in seafood products. However, there exist no commercial methods for detecting Anisakis proteins in food. Furthermore, only a few methods have been validated
Maciej Kochanowski +7 more
doaj +1 more source
Co-oxidation kinetic model for the thermal oxidation of polyethylene-unsaturated substrate systems [PDF]
The thermal oxidation of polyethylene (PE) impregnated by the methyl esters of unsaturated fatty acids (UFEs) was studied using chemiluminescence, and infra-red spectrophotometry.
FAYOLLE, Bruno +3 more
core +5 more sources
Characterisation of Flame Development with Hydrous and Anhydrous Ethanol Fuels in a Spark-Ignition Engine with Direct Injection and Port Injection Systems [PDF]
This paper presents a study of the combustion mechanism of hydrous and anhydrous ethanol in comparison to iso-octane and gasoline fuels in a single-cylinder spark-ignition research engine operated at 1000 rpm with 0.5 bar intake plenum pressure.
Aleiferis, PG, Augoye, AK
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A novel profluorescent dinitroxide for imaging polypropylene degradation [PDF]
Free-radical processes underpin the thermo-oxidative degradation of polyolefins. Thus, to extend the lifetime of these polymers, stabilizers are generally added during processing to scavenge the free radicals formed as the polymer degrades.
Fairfull-Smith, Kathryn E. +4 more
core +2 more sources
Nox2 dependent redox-regulation of microglial response to amyloid-β stimulation and microgliosis in aging [PDF]
Microglia express constitutively a Nox2 enzyme that is involved in neuroinflammation by the generation of reactive oxygen species (ROS). Amyloid β (Aβ) plays a crucial role in Alzheimer’s disease.
Fan, Lampson M. +4 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Experimental Investigation on Self-Excited Thermoacoustic Instability in a Rijke Tube
The experimental investigations into the thermoacoustic instability in a Rijke tube are presented. In order to capture the dynamics of the temperature, a single-ended tunable diode laser absorption spectroscopy (TDLAS) technique was developed, with a ...
Liezhao Luo +5 more
doaj +1 more source

