Results 61 to 70 of about 426,746 (287)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Peroxidase activity of the rat blood at prolonged intake of 137Cs [PDF]
Ядерна фізика та енергетика, 2013 Investigated peroxidase activity of blood white nonlinear rats-males by daily oral administration of 15 kBq 137Cs by chemiluminescence. Discovered oscillatory nature of the changes chemiluminescent indicators peroxi-dase oxidation of blood, the maximum ...
Yu. P. Grynevych +4 more
doaj
Chemosensors, 2022 Superoxide anion is a reactive oxygen species (ROS) of biological interest. More specifically, it plays a role in intra- and intercellular signaling, besides being associated with conditions such as inflammation and cancer.
José Pedro Silva +3 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Chemiluminescence: From mechanism to applications in biological imaging and therapy
Aggregate, 2021 Chemiluminescence (CL) is an emission phenomenon induced by chemical reaction. Different from the photoluminescence, CL is free from external excitation source, which is expected to show great advantages such as higher signal‐to‐background ratio (SBR) in
Zhijia Wang +5 more
doaj +1 more source
Porous glass makes effective substrate for ozone-sensing reagent [PDF]
, 1965 Porous-glass substrate is used for absorption of a dye used in measuring the concentration of atmospheric ozone at high altitudes. This measurement is based on the chemiluminescence produced in the reaction between ozone and the dye, rhodamine B.
core +1 more source
Duality of β-glucan microparticles: antigen carrier and immunostimulants [PDF]
, 2016 Designing efficient recombinant mucosal vaccines against enteric diseases is still a major challenge. Mucosal delivery of recombinant vaccines requires encapsulation in potent immunostimulatory particles to induce an efficient immune response. This paper
Baert, Kim +4 more
core +2 more sources
Electrogenerated Chemiluminescence Biosensing [PDF]
Analytical Chemistry, 2019 This Feature simply introduces the history and mechanism of classical electrogenerated chemiluminescence (ECL) systems for the detection of biomolecules, highlights new advances and emerging fields of the ECL biosensing with recent illustrative examples, and presents the challenges and perspectives of ECL biosensing.
Honglan Qi, Chengxiao Zhang
openaire +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Chemiluminescence vs hemagglutination assay in the detection of Anti-Treponema pallidum antibodies [PDF]
Medical Laboratory JournalBackground: Syphilis has serious consequences for human health and poses challenges for biological diagnosis. Techniques such as chemiluminescence are still poorly known in our context.
Toukam Michel +6 more
doaj