Results 111 to 120 of about 1,594,384 (300)

Figure-of-merit calculation methods for organic heat-pipe fluids [PDF]

open access: yes
With only chemical formulas and operating temperatures specified, selected correlating equations and tables of chemistry-effect functions allow estimates of figures of merit for organic heat-pipe ...
Morris, J. F.
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

The pH and ionic composition of the sub-embryonic fluid of the Japanese quail (Coturnix c. japonica) [PDF]

open access: yes, 2005
The current theory of acid-base chemistry regards [H+] as a dependent variable: changes in pH of a fluid can only occur by alteration of strong ion concentrations ([Na+], [K+], [Cl-]).
Baggott, Glenn K., Pellet-Many, C
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Students’ & Faculty Members’ Attitudes Towards Learning and Teaching Reaction Mechanisms in Organic Chemistry

open access: yesEducation Sciences
Organic Chemistry has typically been identified as a difficult course for many undergraduate students and has a notoriously high failure rate. The part of the subject dealing with reaction mechanisms is considered the most challenging area, and several ...
Oluwatobi Odeleye, Nghiem Tieu
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Plasma chemistry and organic synthesis [PDF]

open access: yes
The characteristic features of chemical reactions using low temperature plasmas are described and differentiated from those seen in other reaction systems. A number of examples of applications of plasma chemistry to synthetic reactions are mentioned. The
Tezuka, M.
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Physical Chemistry meets Organic Chemistry: Special Issue on Physical Organic Chemistry in ChemPhysChem

open access: yesChemPhysChem
Professor François Terrier, Emeritus Professor of the University of Versailles Saint‐Quentin, Versailles, France, passed away in July 2024. He was a key figure in physical organic chemistry and a pioneer in this field in Europe. The breadth of Prof. Terrier's contribution to science was remarkable.
Berionni, Guillaume   +3 more
openaire   +3 more sources

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