Results 91 to 100 of about 7,696,668 (294)

Organic Chemistry II

, 2003
Intermediate organic chemistry. Synthesis, structure determination, mechanism, and the relationships between structure and reactivity emphasized. Special topics in organic chemistry included to illustrate the role of organic chemistry in biological ...
Tabacco, Sarah A., Jamison, Timothy F.
core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Maintaining ecological soil functions - techniques in organic farming systems [PDF]

, 2000
The ecological soil functions (e.g. habitat and living space, production and utilization, ecological regulation) have to be taken into account and maintained by farming systems.
Beste, Andrea
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Organic chemistry. History and mutual relations of universities of Russia [PDF]

, 2017
© 2017, Pleiades Publishing, Ltd. The review describes the history of development of organic chemistry in higher schools of Russia over a period of 170 years, since the emergence of organic chemistry in our country till ...
Petrov M., Nenaidenko V., Aksenova I., Fedotova O., Kriven’ko A., Borisova T., Solod O., Yakovlev I., Aksenov A., Rogozhnikov S., Kiryushkin A., Kolobov A., Beletskaya I., Levina A., Baukov Y., Aksenov N., Kazymova M., Sivova N., Kuznetsova L., Ostrovskii V., Traven’ V., Malinovskaya Y., Shchekotikhin A., Shurov S., Kuznetsov M., Dodonov V., Lesina Y., Beloglazkina E., Vasilyev A., Kustova T., Gushchin A., Stuzhin P., Pchelintseva N., Klimochkin Y., Ustynyuk Y., Makarenko S., Klyuev M., Chupakhin O., Kuryatnikov V., Ishchenko M., Charushin V., Klimochkina A., Fedorov A., Orlov V., Solov’ev P., Malina E., Zhuravlev O., Plakhtinskii V., Antipin I., Krasnokutskaya E., Khelevina O., Fisyuk A., Ivanov I., Pozharskaya N., Varlamov A., Negrebetskii V., Trishin Y., Voronchikhina L.   +57 more
core  

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Covalent Organic Frameworks—Organic Chemistry Beyond the Molecule [PDF]

, 2017
The synthesis of organic molecules has at its core, purity, definitiveness of structure, and the ability to access specific atoms through chemical reactions.
Christian S. Diercks, Yaghi, Omar M, Markus Kalmutzki, Christian Diercks, Omar M. Yaghi, Markus J. Kalmutzki, Kalmutzki, Markus J, Diercks, Christian S, Omar Yaghi   +8 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source