Results 31 to 40 of about 1,576,990 (299)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

The cometary composition of a protoplanetary disk as revealed by complex cyanides

open access: yes, 2015
Observations of comets and asteroids show that the Solar Nebula that spawned our planetary system was rich in water and organic molecules. Bombardment brought these organics to the young Earth's surface, seeding its early chemistry.
A Dutrey   +64 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Impact of cognitive abilities on performance in organic chemistry

open access: yesChemistry Teacher International, 2023
The purpose of this study was to observe the relationship between students’ cognitive abilities and their performance in organic chemistry. We were interested in measuring whether some cognitive composites were more predictive than others on organic ...
Nedungadi Sachin, Shenoy Sunaina
doaj   +1 more source

How do Structural Formulas Embody the Theory of Organic Chemistry? [PDF]

open access: yes, 2008
Organic chemistry provides fertile ground for scholars interested in understanding the role of non-linguistic representations in scientific thinking. In this discipline, it is plausible to think of textual representation as supplementing theories whose ...
Goodwin, William
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Selective synthesis of meta-phenols from bio-benzoic acids via regulating the adsorption state

open access: yesiScience, 2023
Summary: Phenols are important building blocks widely applied in many fields. The pronounced orientational effect of the phenolic hydroxyl group makes achieving selective synthesis of meta-phenols challenging.
Xinze Du   +4 more
doaj   +1 more source

Interdisciplinary Research-Based Learning in Organic Chemistry and Microbiology Laboratories: Synthesis and Biological Testing of Novel Penicillin Derivatives [PDF]

open access: yes, 2015
Interests in the mechanism that penicillin bestows on its target protein has driven the curiosity of its binding specificity towards the methicillin resistant strain of Staphylococcus areus, and its expression of a unique penicillin binding protein that ...
Rehberger, Kyle R.
core   +1 more source

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