Results 21 to 30 of about 1,924,905 (240)

Citric Acid: A Multifunctional Pharmaceutical Excipient

Pharmaceutics, 2022
Citric acid, a tricarboxylic acid, has found wide application in the chemical and pharmaceutical industry due to its biocompatibility, versatility, and green, environmentally friendly chemistry.
M. Lambros, Thac (Henry) Tran, Q. Fei, M. Nicolaou   +3 more
semanticscholar   +1 more source

Botanical Sources, Chemistry, Analysis, and Biological Activity of Furanocoumarins of Pharmaceutical Interest

Molecules, 2019
The aim of this work is to provide a critical review of plant furanocoumarins from different points of view, including their chemistry and biosynthetic pathways to their extraction, analysis, and synthesis, to the main biological activities found for ...
R. Bruni, D. Barreca, M. Protti, Virginia Brighenti, L. Righetti, Lisa Anceschi, L. Mercolini, S. Benvenuti, G. Gattuso, Federica Pellati   +9 more
semanticscholar   +1 more source

Prediction of the permeability of neutral drugs inferred from their solvation properties [PDF]

, 2015
Determination of drug absorption is an important component of the drug discovery and development process in that it plays a key role in the decision to promote drug candidates to clinical trials.
Milanetti, Edoardo, Raimondo, Domenico, Tramontano, Anna   +2 more
core   +1 more source

Direct measurement of molecular mobility and crystallisation of amorphous pharmaceuticals using terahertz spectroscopy. [PDF]

, 2016
Despite much effort in the area, no comprehensive understanding of the formation and behaviour of amorphous solids has yet been achieved. This severely limits the industrial application of such materials, including drug delivery where, in principle ...

core   +2 more sources

Fate of drugs during wastewater treatment [PDF]

, 2013
This is the post-print version of the final paper published in TrAC Trends in Analytical Chemistry. The published article is available from the link below.
Andrási, Bagnall, Baker, Baker, Barceló, Bedding, Bernhard, Brodin, Bruce Petrie, Buisson, Carbonaro, Chen, Chiaia-Hernandez, Chiu, Clara, Coelho, Duan, Elise Cartmell, Ewan J. McAdam, Ferrer, Galus, Gardner, Gaulke, Gomes, Gomes, Gomes, Gong, Grabic, Gracia-Lor, Gros, Gros, Grover, Guibaud, Gunnarsson, Göbel, Hashimoto, Helbling, Hignite, Ho, Hoigne, Huber, Huber, Huntscha, Hörsing, Ifelebuegu, Jelic, John N. Lester, Jones, Jones, Jones, Jones, Joss, Kasprzyk-Hordern, Khunjar, Kim, Kimura, Kosjek, Kreuzinger, Langford, Lishman, López-Serna, López-Serna, Marchese, Mark D. Scrimshaw, Matamoros, Maurer, McAdam, Metcalfe, Nakada, Nakada, Nieto, Ort, Ort, Petrie, Radjenovic, Radjenović, Reungoat, Robertson, Rosal, Samaras, Schaar, Sebők, Shen, Silva, Snyder, Snyder, Sumpter, Ternes, Ternes, Urase, Vader, Wagner, Wu, Wunder, Yang, Zearley, Zhao, Zorita, Zuloaga   +98 more
core   +2 more sources

Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited

, 2018
In 2007 the members of the ACS Green Chemistry Institute® Pharmaceutical Roundtable assembled a list of key green chemistry research areas to both identify transformations that would benefit from improvements in process greenness and to encourage ...
M. Bryan, P. Dunn, D. Entwistle, F. Gallou, S. Koenig, J. Hayler, M. Hickey, S. Hughes, M. Kopach, G. Moine, P. Richardson, F. Roschangar, A. Steven, F. Weiberth   +13 more
semanticscholar   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Impact of continuous flow chemistry in the synthesis of natural products and active pharmaceutical ingredients.

Anais da Academia Brasileira de Ciências, 2018
We present a comprehensive review of the advent and impact of continuous flow chemistry with regard to the synthesis of natural products and drugs, important pharmaceutical products and definitely responsible for a revolution in modern healthcare.
J. M. D. Souza, Renan S. Galaverna, A. A. Souza, T. Brocksom, J. Pastre, Rodrigo O. M. A. Souza, K. T. Oliveira   +6 more
semanticscholar   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Supramolecular Pharmaceutical Sciences: A Novel Concept Combining Pharmaceutical Sciences and Supramolecular Chemistry with a Focus on Cyclodextrin-Based Supermolecules.

Chemical and pharmaceutical bulletin, 2018
Supramolecular chemistry is an extremely useful and important domain for understanding pharmaceutical sciences because various physiological reactions and drug activities are based on supramolecular chemistry.
T. Higashi, Daisuke Iohara, K. Motoyama, H. Arima   +3 more
semanticscholar   +1 more source