Results 1 to 10 of about 28,995,883 (293)

Development of a pharmaceutical science systematic review process using a semi‐automated machine learning tool: Intravenous drug compatibility in the neonatal intensive care setting [PDF]

Pharmacology Research & Perspectives
Our objective was to establish and test a machine learning‐based screening process that would be applicable to systematic reviews in pharmaceutical sciences.
D. Thisuri N. De Silva, Brioni R. Moore, Tobias Strunk, Michael Petrovski, Vanessa Varis, Kevin Chai, Leo Ng, Kevin T. Batty   +7 more
doaj   +2 more sources

Biological Impact of Phenolic Compounds from Coffee on Colorectal Cancer

Pharmaceuticals, 2021
Colorectal cancer is one of the leading death-related diseases worldwide, usually induced by a multifactorial and complex process, including genetic and epigenetic abnormalities and the impact of diet and lifestyle. In the present study, we evaluated the
Hernán Villota, Manuel Moreno-Ceballos, Gloria A. Santa-González, Diego Uribe, Isabel Cristina Henao Castañeda, Lina María Preciado, Johanna Pedroza-Díaz   +6 more
doaj   +1 more source

Anti-obesity activity of Cymbopogon citratus (lemongrass): A systematic review [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Obesity represents a significant global health challenge. The limited efficacy and possible side effects of available anti-obesity agents highlight the need to find new, effective, and safe agents. Lemongrass (Cymbopogon citratus) is an aromatic
Musthika Wida Mashitah, Nashi Widodo, Nur Permatasari, Achmad Rudijanto   +3 more
doaj   +1 more source

The effect of ethanol-based coriander (Coriandrum sativum L.) seed extract on oxidative stress, antioxidant level and cellular senescence in the heart of obese rat [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: High-fat diets contribute to oxidative stress and trigger cellular senescence through an imbalance in reactive oxygen species. The potential of coriander (Coriandrum sativum) seed, known for its therapeutic properties against oxidative stress ...
Irah Namirah, Kayla S. Wimbanu, Albertus M.E. Rompies, Yosafat S. Prayogo, Wawaimuli Arozal, Fadilah, Muhammad Hanafi, Novi S. Hardiany   +7 more
doaj   +1 more source

A comparative study of the chemical composition and antioxidant capacity of the essential oils from three species of Mentha cultivated in Morocco [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Mentha species are well known for their health benefits. Products extracted from aromatic plants of this genus (Mentha) are increasingly being studied for their active constituents in order to replace synthetic products that are harmful to ...
Arrahmouni Rayan, Ouazzani Chadia, Er-Ramly Azzedine, Moustaghfir Abdellah, Benchama Zakaria, Elamrani Abdelaziz, Benkhouili Fatima Zahra, El-Guourrami Otman, Dami Abdallah, Balouch Lhousaine   +9 more
doaj   +1 more source

Antioxidant potential and xanthine oxidase inhibition of flavonol glycosides from Phyllanthus emblica L. leaves [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Hyperuricemia is the cause of gout in the inflammatory joint condition. The xanthine oxidase enzyme is a therapeutic target for gout treatment because it plays a role in the generation of uric acid. Allopurinol is used to treat gout. It prevents
Husnunnisa, Rika Hartati, Rachmat Mauludin, Muhamad Insanu   +3 more
doaj   +1 more source

Development of asialoglycoprotein receptor directed nanoparticles for selective delivery of curcumin derivative to hepatocellular carcinoma

Heliyon, 2018
Hepatocellular cellular carcinoma (HCC) is one of the most challenging liver cancer subtypes. Due to lack of cell surface biomarkers and highly metastatic nature, early detection and targeted therapy of HCC is an unmet need.
Shaimaa Yousef, Hashem O. Alsaab, Samaresh Sau, Arun K. Iyer   +3 more
doaj   +1 more source

Mono- and combinational drug therapies for global viral pandemic preparedness

iScience, 2022
Summary: Broadly effective antiviral therapies must be developed to be ready for clinical trials, which should begin soon after the emergence of new life-threatening viruses.
Aleksandr Ianevski, Rouan Yao, Ronja M. Simonsen, Vegard Myhre, Erlend Ravlo, Gerda D. Kaynova, Eva Zusinaite, Judith M. White, Stephen J. Polyak, Valentyn Oksenych, Marc P. Windisch, Qiuwei Pan, Eglė Lastauskienė, Astra Vitkauskienė, Algimantas Matukevičius, Tanel Tenson, Magnar Bjørås, Denis E. Kainov   +17 more
doaj   +1 more source

Effects of intermittent restriction diet and moderate-intensity exercise on the expression of cardiomyocytes in mice with high-glucose loads [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: The prevalence of obesity was 8% in 2002 and increased to 11.5% in 2011 in Indonesia. The results of the 2018 Basic Health Research stated that 13.6% of people over the age of 18 were overweight, and 21.8% were obese.
Eka Arum Cahyaning Putri, Gosy Endra Vigriawan, Hayuris Kinandita Setiawan, Zulhabri Othman, Yudi Her Oktaviano, Lilik Herawati   +5 more
doaj   +1 more source

Enhanced anticancer effect of cetuximab combined with ethanol extract of Volvariella volvacea in colorectal cancer targeted TOP2A and PPARγ [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Colorectal cancer (CRC) is a major global health concern as innovative therapeutic strategies to enhance treatment outcomes. This study investigates the therapeutic potential of the ethanol extract derived from Volvariella volvacea in ...
Sofy Permana, Elsafira A. Nabilahasna, Fairuz A. Meilany, Silvi Zakiyatul Ilmiyah, Edwin Widodo, Eviana Norahmawati, Yoshiyuki Kawamoto, Heni Endrawati, Agustina T. Endharti   +8 more
doaj   +1 more source