Results 1 to 10 of about 1,233,997 (314)
ChemInform, 2002 AbstractFor Abstract see ChemInform Abstract in Full Text.
Blunt, J.W. +4 more
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Pseudo Natural Products—Chemical Evolution of Natural Product Structure [PDF]
Angewandte Chemie International Edition, 2021 AbstractPseudo‐natural products (PNPs) combine natural product (NP) fragments in novel arrangements not accessible by current biosynthesis pathways. As such they can be regarded as non‐biogenic fusions of NP‐derived fragments. They inherit key biological characteristics of the guiding natural product, such as chemical and physiological properties, yet ...
George Karageorgis +4 more
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Natural product-based PROteolysis TArgeting Chimeras (PROTACs) [PDF]
, 2022 Covering: upto 2022 Natural products have an embedded recognition of protein surfaces. They possess this property as they are produced by biosynthetic enzymes and are substrates for one or more enzymes in the biosynthetic pathway. The inherent advantages,
Liu, Miaomiao +2 more
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Streptomyces cell-free systems for natural product discovery and engineering [PDF]
, 2022 Streptomyces bacteria are a major microbial source of natural products, which are encoded within so-called biosynthetic gene clusters (BGCs). This highlight discusses the emergence of native Streptomyces cell-free systems as a new tool to accelerate the ...
Lai, H-E +7 more
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Antioxidants, 2022 With the recent development of chemical analysis technology, attention has been placed on natural light-sensitive compounds that exhibit photoreactivity to expand the structural diversity of natural product chemistry. Photochemical reactions that proceed
InWha Park +6 more
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Natural Products and Neuroprotection [PDF]
International Journal of Molecular Sciences, 2019 Neurodegenerative diseases are among the most serious health problems affecting millions of people worldwide, and their incidence is dramatically growing together with increased lifespan [...]
Cristina Angeloni, David Vauzour
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Natural Product Reports, 2023 In natural products, a low optical purity is not generally associated with a sloppy enzymatic activity, but rather with the co-expression of antipodal enzymes/directing proteins or, alternatively, with erosion by enzymatic or spontaneous reactions.
Mazzotta, Sarah +5 more
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Microbiology Spectrum, 2022 Serine palmitoyltransferase catalyzes the first step of the sphingolipid biosynthesis. Recently, sphingolipid homeostasis has been connected to several human diseases, making serine palmitoyltransferases an interesting therapeutic target.
Sandra Hoefgen +6 more
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Molecules, 2021 Tyrosinase is an enzyme that plays a crucial role in the melanogenesis of humans and the browning of food products. Thus, tyrosinase inhibitors that are useful to the cosmetic and food industries are required.
Prasannavenkatesh Durai +4 more
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Limonene as natural product extraction solvent [PDF]
, 2023 First reported in 2004, and subsequently advanced by Chemat’s and other research teams in the following two decades, the use of d-limonene as natural product extraction solvent offers multiple benefits that go beyond its environmentally benign nature ...
Mario, Pagliaro +2 more
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