Results 11 to 20 of about 1,233,997 (314)

From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris

open access: yesVirulence, 2022
Candida species are a major cause of invasive fungal infections. While Candida albicans, C. glabrata, C. parapsilosis, and C. tropicalis are the most dominant species causing life-threatening candidiasis, C.
Stefanie Allert   +8 more
doaj   +1 more source

Minerals Composition and Characterization of the Hatchery Eggshell Waste Treated with Different Preparation Methods

open access: yesJurnal Ilmu dan Teknologi Hasil Ternak, 2021
The preparation process needs to be carried out in the treatment of hatchery waste. The objective of the study was to determine the mineral content and characterization of the eggshell waste after preparation.
Ahmad Iskandar Setiyawan   +3 more
doaj   +1 more source

Antioxidants of Natural Products [PDF]

open access: yesAntioxidants, 2021
Antioxidant ingredients are known to contribute to the beneficial effects of natural products in health promotion as well as disease prevention by reducing oxidative stress, caused by reactive oxygen or nitrogen species, in biological systems [...]
openaire   +3 more sources

Natural Product Scores and Fingerprints Extracted from Artificial Neural Networks. [PDF]

open access: yes, 2021
Due to their desirable properties, natural products are an important ligand class for medicinal chemists. However, due to their structural distinctiveness, traditional cheminformatic approaches, like ligand-based virtual screening, often perform worse ...
Joana, Massa   +2 more
core   +1 more source

Evolutionary chemical binding similarity approach integrated with 3D-QSAR method for effective virtual screening

open access: yesBMC Bioinformatics, 2020
Background Despite continued efforts using chemical similarity methods in virtual screening, currently developed approaches suffer from time-consuming multistep procedures and low success rates.
Prasannavenkatesh Durai   +3 more
doaj   +1 more source

Bioactive natural products from Bacteroidetes [PDF]

open access: yes, 2022
10451065Bacteria representing the phylum Bacteroidetes produce a diverse range of natural products, including polyketides, peptides and lactams. Here, we discuss unique aspects of the bioactive compounds discovered thus far, and the corresponding ...
Spohn, Marius S.   +2 more
core   +1 more source

Self-Protection against the Sphingolipid Biosynthesis Inhibitor Fumonisin B1 Is Conferred by a FUM Cluster-Encoded Ceramide Synthase

open access: yesmBio, 2020
Fumonisin (FB) mycotoxins produced by species of the genus Fusarium detrimentally affect human and animal health upon consumption, due to the inhibition of ceramide synthase.
Slavica Janevska   +7 more
doaj   +1 more source

A Natural Love of Natural Products [PDF]

open access: yesThe Journal of Organic Chemistry, 2008
Recent research on the chemistry of natural products from the author's group that led to the receipt of the ACS Ernest Guenther Award in the Chemistry of Natural Products is reviewed. REDOR NMR and synthetic studies established the T-taxol conformation as the bioactive tubulin-binding conformation, and these results were confirmed by the synthesis of ...
openaire   +2 more sources

Iterative machine learning-based chemical similarity search to identify novel chemical inhibitors

open access: yesJournal of Cheminformatics, 2023
Machine learning-based chemical screening has made substantial progress in recent years. However, these predictions often have low accuracy and high uncertainty when identifying new active chemical scaffolds.
Prasannavenkatesh Durai   +4 more
doaj   +1 more source

Molecular Docking of Soybean (Glycine max) Seed and Ginger (Zingiber officinale) Rhizome Components as Anti-Diabetic Through Inhibition of Dipeptidyl Peptidase 4 (DPP-4) and Alpha-Glucosidase Enzymes [PDF]

open access: yes, 2021
[ARCHIVES] Copyright Article From:Tropical Journal of Natural Product Research (TJNPR)Dipeptidyl Peptidase-4 (DPP-4) and alpha-glucosidase (α-glucosidase) are enzymes involved in carbohydrate metabolism.
Hakim, Reza   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy