Results 11 to 20 of about 4,560,586 (338)

Self-Protection against the Sphingolipid Biosynthesis Inhibitor Fumonisin B1 Is Conferred by a FUM Cluster-Encoded Ceramide Synthase

open access: yesmBio, 2020
Fumonisin (FB) mycotoxins produced by species of the genus Fusarium detrimentally affect human and animal health upon consumption, due to the inhibition of ceramide synthase.
Slavica Janevska   +7 more
doaj   +1 more source

Iterative machine learning-based chemical similarity search to identify novel chemical inhibitors

open access: yesJournal of Cheminformatics, 2023
Machine learning-based chemical screening has made substantial progress in recent years. However, these predictions often have low accuracy and high uncertainty when identifying new active chemical scaffolds.
Prasannavenkatesh Durai   +4 more
doaj   +1 more source

Natural Diagonal Riemannian Almost Product and Para-Hermitian Cotangent Bundles [PDF]

open access: yes, 2009
We obtain the natural diagonal almost product and locally product structures on the total space of the cotangent bundle of a Riemannian manifold. We find the Riemannian almost product (locally product) and the (almost) para-Hermitian cotangent bundles of
A. Al-Aqeel   +64 more
core   +2 more sources

Bioactive Natural Products [PDF]

open access: yesJournal of Chemistry, 2013
Bioactive natural products have never ceased to play an important role in the search of novel therapeutic agents. Natural products from the nature such as the plant and marine sources form an integral part of the living system, and they have existed ever since the beginning of life.Therefore, it is undeniable that works related to natural products ...
Hadi, A. Hamid A.   +2 more
openaire   +2 more sources

Natural product diversity of actinobacteria in the Atacama Desert [PDF]

open access: yes, 2018
Natural Product diversityPeer reviewedPublisher ...
Ebel, Rainer   +2 more
core   +3 more sources

SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis. [PDF]

open access: yes, 2017
Pericyclic reactions-which proceed in a concerted fashion through a cyclic transition state-are among the most powerful synthetic transformations used to make multiple regioselective and stereoselective carbon-carbon bonds.
Chen, Mengbin   +9 more
core   +1 more source

Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]

open access: yes, 2016
The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D.   +2 more
core   +2 more sources

Analysis of food supplement with unusual raspberry ketone content [PDF]

open access: yes, 2016
In recent years food supplement market increased constantly, including slimming products and against obesity. The case of rasberry ketone (RK) is here reported.
Foddai, S.   +6 more
core   +1 more source

Marine natural products

open access: yesNat. Prod. Rep., 2012
This review of marine natural products for 2014 describes 1378 new compounds and reports structural revisions or assignments of absolute configuration for previously reported compounds. Since 1965 MNP chemists have made ∼9000 collections worldwide yielding ∼25 700 new MNPs. The rate of discovery of MNPs by region is examined in this review.
John W. Blunt   +4 more
openaire   +12 more sources

Antiviral effect of ovotransferrin in mouse peritoneal macrophages by up-regulating type I interferon expression

open access: yesFood and Agricultural Immunology, 2018
Ovotransferrin (OVT) is one of the major proteins in avian albumen that exerts diverse biological activities. This study is aimed to investigate the antiviral effect and mechanism of OVT from the avian egg.
Yulan Zhou   +6 more
doaj   +1 more source

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