Results 21 to 30 of about 7,942,931 (308)
Natural Product Scores and Fingerprints Extracted from Artificial Neural Networks. [PDF]
, 2021 Due to their desirable properties, natural products are an important ligand class for medicinal chemists. However, due to their structural distinctiveness, traditional cheminformatic approaches, like ligand-based virtual screening, often perform worse ...
Joana, Massa +2 more
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Natural products genomics [PDF]
Microbial Biotechnology, 2008 Secondary metabolites (or natural products) are often synthesized by multi‐modular, multi‐domain proteins called non‐ribosomal peptide synthetases (NRPS) and polyketide synthases (PKS). Various well‐known metabolites produced by microorganisms are listed in Table 1, and examples of structures are shown in Fig. 1. In particular, Streptomyces species are
Siezen, R.J., Khayatt, B.
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Natural Products for Medicine [PDF]
Journal of Biomedicine and Biotechnology, 2012 Throughout human history, natural products—including terrestrial plants, animal products, marine organisms, and products of microorganismal fermentation—have been used in traditional medicines. This historical experience with natural products as therapeutic agents has evolved to sophisticated isolation of active chemical entities from ...
Shibata, Masa-Aki +3 more
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Cell factory engineering for improved production of natural products [PDF]
, 2019 Natural product biosynthesis is inherently linked with the primary metabolism in terms of providing precursors and co-factors. Thus, even though it is important to improve the performance of natural product biosynthetic enzymes in building efficient cell
Nielsen, Jens +2 more
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Nat. Prod. Rep., 2012 This review of marine natural products for 2014 describes 1378 new compounds and reports structural revisions or assignments of absolute configuration for previously reported compounds. Since 1965 MNP chemists have made ∼9000 collections worldwide yielding ∼25 700 new MNPs. The rate of discovery of MNPs by region is examined in this review.
John W. Blunt +4 more
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Applied Biological Chemistry, 2023 YPL-001 is a drug substance of Pseudolysimachion rotundum var. subintegrum and has been reported to be a potent COPD inhibitor. For the first time, this study demonstrated a correlation among the iridoid constituents, antioxidants, and MUC5AC inhibition ...
Soobin Song +13 more
doaj +1 more source
Shipin gongye ke-ji, 2022 This study systematically determined the nutrient components, bioactive substances and heavy metal content of Stropharia rugosoannulata in Bo’ai County, and its nutritional value was analyzed and evaluated.
Bingnian JING +7 more
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Frontiers in Microbiology, 2015 Opportunistic fungal pathogens can cause bloodstream infection and severe sepsis upon entering the blood stream of the host. The early immune response in human blood comprises the elimination of pathogens by antimicrobial peptides and innate immune cells,
Teresa eLehnert +5 more
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Anticancer Effects of Seaweed-Derived Bioactive Compounds
Applied Sciences, 2021 Cancer remains a major life-threatening disease worldwide. The development of anticancer drugs using natural products obtained from marine organisms has been proposed as an alternative approach.
Heesu Lee, Baskar Selvaraj, Jae Wook Lee
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Memòria resum d’actuacions Parc Natural dels Ports 2021 [PDF]
, 2022 Gestió efectuada durant el 2021 al Parc Natural dels Ports, destacar les accions estratègiques i les fites més rellevants en cada un dels àmbits i línies de treball.[es] Gestión efectuada durante el 2021 en el Parque Natural de Els Ports, destaca las ...
Parc Natural dels Ports
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