Results 31 to 40 of about 7,942,931 (308)

Marine Natural Products [PDF]

, 2002
(2003: journal publication date)This review covers the literature published in 2001 for marine natural products, with 495 citations (365 for the period January to December 2001) referring to 793 compounds isolated from marine microorganisms and ...
Copp, Brent, Copp, B.R., Prinsep, MR, Northcote, PT, Blunt, J.W., Blunt, JW, Prinsep, M.R., Munro, M.H.G., Northcote, P.T., Munro, MHG   +9 more
core   +1 more source

Natural Products and Inflammation [PDF]

Molecules, 2017
Inflammation (or inflammatory reaction) is the response to body aggression by a pathogen agent, an allergen, a toxic compound, a tissue lesion, etc.[...]
openaire   +3 more sources

68 million natural product-like compound database generated via molecular language processing [PDF]

, 2023
Natural products are a rich resource of bioactive compounds for valuable applications across multiple fields such as food, agriculture, medicine. For natural product discovery, high throughput in silico screening offers a cost-effective alternative to ...
Shi Jun, Ang, Krishnan, Adaikkappan, Yee Hwee, Lim, Naythan, Yeo Zhen Xi, Dillon, Tay Wei Peng   +4 more
core   +1 more source

Lactic Acid Bacteria Isolates and the Microbiome of Cincalok, Tempoyak, and Mandai: A Traditional Fermented Food from Kalimantan Island, Indonesia

International Journal of Food Science
Indonesia has abundant traditional fermented food with various lactic acid bacteria (LAB), which can be developed into probiotics for pharmaceutical and functional food and feed products.
Retno Murwani, Refa Anggraeni, Gregorius Nico Adi Setiawan, Putri Dyah Astari, Ni Kadek Dita Cahyani, Mada Triandala Sibero, Ambariyanto Ambariyanto   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Discovery of 15-deoxynaphthomycins activating the antioxidant NRF2-ARE pathway from Streptomyces sp. N50 via genome mining, global regulator introduction, and molecular networking

Microbial Cell Factories
Genome mining is a promising avenue for expanding the repertoire of microbial natural products, which are important for drug development. This approach involves predicting genetically encoded small molecules by examining bacterial genomes via accumulated
Min-Seon Kim, Baskar Selvaraj, Hee-Tae Yeo, Jun-Su Park, Jae Wook Lee, Jin-Soo Park   +5 more
doaj   +1 more source

Automated quantification of the phagocytosis of Aspergillus fumigatus conidia by a novel image analysis algorithm

Frontiers in Microbiology, 2015
Studying the pathobiology of the fungus Aspergillus fumigatus has gained a lot of attention in recentyears. This is due to the fact that this fungus is a human pathogen that can cause severe diseases, likeinvasive pulmonary aspergillosis in ...
Kaswara eKraibooj, Hanno eSchoeler, Carl Magnus Svensson, Axel A Brakhage, Marc Thilo eFigge   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Regional comparison study of Epimedium koreanum using UHPLC-QTOF/MS-based metabolomics approach

Applied Biological Chemistry
The untargeted metabolomics-based molecular networking approach combined with multivariate analysis, proves to be an effective strategy for distinguishing raw materials in herbal medicine according to specific criteria.
Alfan Danny Arbianto, Min Kim, Seon Min Oh, Hyun-Jae Jang, Hyung Won Ryu, Jin-Hyub Paik, Sei-Ryang Oh, Jongmin Ahn   +7 more
doaj   +1 more source

A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster

Frontiers in Microbiology, 2015
Recently, the Aspergillus terreus terrein gene cluster was identified and selected for development of a new heterologous expression system. The cluster encodes the specific transcription factor TerR that is indispensable for terrein cluster induction. To
Markus eGressler, Peter eHortschansky, Elena eGeib, Matthias eBrock, Matthias eBrock   +4 more
doaj   +1 more source