Results 31 to 40 of about 1,233,997 (314)

Natural Products for Medicine [PDF]

open access: yesJournal of Biomedicine and Biotechnology, 2012
Throughout human history, natural products—including terrestrial plants, animal products, marine organisms, and products of microorganismal fermentation—have been used in traditional medicines. This historical experience with natural products as therapeutic agents has evolved to sophisticated isolation of active chemical entities from ...
Shibata, Masa-Aki   +3 more
openaire   +2 more sources

Bottom-up modeling approach for the quantitative estimation of parameters in pathogen-host interactions

open access: yesFrontiers in Microbiology, 2015
Opportunistic fungal pathogens can cause bloodstream infection and severe sepsis upon entering the blood stream of the host. The early immune response in human blood comprises the elimination of pathogens by antimicrobial peptides and innate immune cells,
Teresa eLehnert   +5 more
doaj   +1 more source

Assessment of iridoid profiles in the growth period of aerial parts of Pseudolysimachion rotundum var. subintegrum and their antioxidant and MUC5AC inhibitory potential

open access: yesApplied Biological Chemistry, 2023
YPL-001 is a drug substance of Pseudolysimachion rotundum var. subintegrum and has been reported to be a potent COPD inhibitor. For the first time, this study demonstrated a correlation among the iridoid constituents, antioxidants, and MUC5AC inhibition ...
Soobin Song   +13 more
doaj   +1 more source

Analysis and Evaluation of Nutrient Components, Bioactive Substances and Heavy Metal Content of Stropharia rugosoannulata in Bo’ai County

open access: yesShipin gongye ke-ji, 2022
This study systematically determined the nutrient components, bioactive substances and heavy metal content of Stropharia rugosoannulata in Bo’ai County, and its nutritional value was analyzed and evaluated.
Bingnian JING   +7 more
doaj   +1 more source

Natural Products for Antithrombosis [PDF]

open access: yesEvidence-Based Complementary and Alternative Medicine, 2015
Thrombosis is considered to be closely related to several diseases such as atherosclerosis, ischemic heart disease and stroke, as well as rheumatoid arthritis, hyperuricemia, and various inflammatory conditions. More and more studies have been focused on understanding the mechanism of molecular and cellular basis of thrombus formation as well as ...
Cen Chen   +5 more
openaire   +2 more sources

Anticancer Effects of Seaweed-Derived Bioactive Compounds

open access: yesApplied Sciences, 2021
Cancer remains a major life-threatening disease worldwide. The development of anticancer drugs using natural products obtained from marine organisms has been proposed as an alternative approach.
Heesu Lee, Baskar Selvaraj, Jae Wook Lee
doaj   +1 more source

Direct construction of vicinal all-carbon quaternary stereocenters in natural product synthesis [PDF]

open access: yes, 2015
Molecules containing vicinal all-carbon quaternary stereocenters are found in many secondary metabolites, and they exhibit a variety of biological and pharmacological activities.
Yang, Zhen   +3 more
core   +1 more source

Bacterial natural product discovery by heterologous expression [PDF]

open access: yes, 2023
Natural products have found important applications in the pharmaceutical and agricultural sectors. In bacteria, the genes that encode the biosynthesis of natural products are often colocalized in the genome, forming biosynthetic gene clusters.
Adjo, Kadjo, Alessandra, Eustaquio
core   +1 more source

Establishment of a Phenotypic-based Sand Dollar Fellaster zelandiae Embryo Development Assay and its Application in Defining the Structure-Activity Relationship of Discorhabdin Alkaloids [PDF]

open access: yes, 2013
An embryo development assay using the common New Zealand intertidal species Fellaster zelandiae (sand dollar) is presented. The assay was validated by comparing activity profiles of a range of discorhabdin alkaloids, natural products sourced from ...
Cropp, Brent R., Grkovic, Tanja
core   +2 more sources

Discovery and characterization of natural products that act as pheromones in fish [PDF]

open access: yes, 2018
Fish use a diverse collection of molecules to communicate with conspecifics. Since Karlson and Luscher termed these molecules 'pheromones', chemists and biologists have joined efforts to characterize their structures and functions. In particular,
Li K(李可)
core   +1 more source

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