Results 41 to 50 of about 8,248,717 (265)

Automated quantification of the phagocytosis of Aspergillus fumigatus conidia by a novel image analysis algorithm

Frontiers in Microbiology, 2015
Studying the pathobiology of the fungus Aspergillus fumigatus has gained a lot of attention in recentyears. This is due to the fact that this fungus is a human pathogen that can cause severe diseases, likeinvasive pulmonary aspergillosis in ...
Kaswara eKraibooj, Hanno eSchoeler, Carl Magnus Svensson, Axel A Brakhage, Marc Thilo eFigge   +4 more
doaj   +1 more source

N-2, N-2, 7-trimethylguanine, a new trimethylated guanine natural product from the New Zealand ascidian, Lissoclinum notti

, 2001
From the New Zealand ascidian, Lissoclinum notti a new natural product, N-2,N-2,7-trimethylguanine (1) has been isolated.
Lambert, G, Babcock, RC, Pearce, AN, Copp, BR   +3 more
core   +1 more source

Strategic Enzymatic Transformations in Modern Natural Product Synthesis [PDF]

, 2022
Enzymes continue to gain recognition as valuable tools in synthetic chemistry as they enable transformations, which elude conventional organochemical approaches.
Felix, Kaspar, Anett, Schallmey, Anett Schallmey, Felix Kaspar   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Regional comparison study of Epimedium koreanum using UHPLC-QTOF/MS-based metabolomics approach

Applied Biological Chemistry
The untargeted metabolomics-based molecular networking approach combined with multivariate analysis, proves to be an effective strategy for distinguishing raw materials in herbal medicine according to specific criteria.
Alfan Danny Arbianto, Min Kim, Seon Min Oh, Hyun-Jae Jang, Hyung Won Ryu, Jin-Hyub Paik, Sei-Ryang Oh, Jongmin Ahn   +7 more
doaj   +1 more source

A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster

Frontiers in Microbiology, 2015
Recently, the Aspergillus terreus terrein gene cluster was identified and selected for development of a new heterologous expression system. The cluster encodes the specific transcription factor TerR that is indispensable for terrein cluster induction. To
Markus eGressler, Peter eHortschansky, Elena eGeib, Matthias eBrock, Matthias eBrock   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Micheliolide ameliorates colon cancer cachexia by modulating gut microbiota–immune signaling via Phocaeicola vulgatus enrichment

Microbiome
Background Cancer cachexia profoundly impacts patient survival and quality of life. Current treatments fail to halt this trajectory, highlighting an urgent clinical need for host-directed therapies capable of uncoupling skeletal muscle wasting from tumor
Hye-Young Youn, Sunhee Park, Huitae Min, Nguyen Bao Ngoc, Young Hyun Kim, Kwang-Hyun Cha, Young Tae Park, Hyog Young Kwon, Choong-Gu Lee, Myungsuk Kim   +9 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Enhanced diastereomeric mixture analysis through integration of quantum chemical calculations with spatio-conformational information obtained from ultraselective NMR techniques

Applied Biological Chemistry
Nuclear Magnetic Resonance (NMR) spectroscopy has become indispensable for elucidating molecular structures in pharmaceutical and natural product chemistry, where precise stereochemical configurations critically determine biological activities and ...
Miyeon Bang, Jin Wook Cha
doaj   +1 more source