Results 21 to 30 of about 3,036,529 (295)

Isolation and identification of phenolic antioxidants from Pistacia integerrima gall and their anticholine esterase activities

Heliyon, 2018
The galls of Pistacia integerrima are utilized in folk medicines for the treatment of cough, asthma, dysentery, liver disorders and for snake bite. A number of biological active compounds like alkaloids, flavonoids, tannins, saponins and sterols from ...
Muhammad Zahoor, Roheena Zafar, Naveed Ur Rahman   +2 more
doaj   +1 more source

Recent Trends in Pharmaceutical Analytical Chemistry

, 2020
Modern analytical chemistry plays a vital role in pharmaceutical sciences [...
Constantinos K. Zacharis, Catherine K. Markopoulou   +1 more
core   +1 more source

Novel 3-((2-chloroquinolin-3-yl)methylene)indolin-2-one derivatives produce anticancer efficacy in ovarian cancer in vitro

Heliyon, 2019
A novel series of 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones were synthesized, using the ‘molecular hybridization approach’ and evaluated for anticancer efficacy.
Chandrabose Karthikeyan, Haneen Amawi, Charles R. Ashby, Jr., Vishwa M. Khare, Veronica Jones, N.S. Hari Narayana Moorthy, Piyush Trivedi, Amit K. Tiwari   +7 more
doaj   +1 more source

The influence of salt formation on electrostatic and compression properties of flurbiprofen salts [PDF]

, 2013
Salt formation is an effective method of improving physicochemical properties of acidic and basic drugs. The selection of a salt form most suitable for drug development requires a well-designed screening strategy to ensure various issues are addressed in
Conway, Barbara R, Laity, Peter R., Šupuk, Enes, Asare-Addo, Kofi, Conway, Barbara R., Panchmatia, Pooja M., Ghori, Muhammad U.   +6 more
core   +1 more source

Silver nanoparticle synthesis by Acalypha wilkesiana extract: phytochemical screening, characterization, influence of operational parameters, and preliminary antibacterial testing

Heliyon, 2019
Single pot green synthesis of silver nanoparticles (AgNPs) was successfully carried out using medicinal plant extract of Acalypha wilkesiana via bottom-up approach. Five imperative operational parameters (pH, contact time, concentration, volume ratio and
Adewumi Oluwasogo Dada, Folahan Amoo Adekola, Fehintoluwa Elizabeth Dada, Adunola Tabitha Adelani-Akande, Micheal Oluwasesan Bello, Chidiogo Rita Okonkwo, Adejumoke Abosede Inyinbor, Abimbola Peter Oluyori, Adeniyi Olayanju, Kolawole Oluseyi Ajanaku, Charles Oluwaseun Adetunji   +10 more
doaj   +1 more source

Syntheses, physicochemical characterization, antibacterial studies on potassium morpholine dithiocarbamate nickel (II), copper (II) metal complexes and their ligands

Heliyon, 2019
Organic molecule dithiocarbamate transition metal complexes are novel and very attractive pharmaceutical targets for the management and control of antibiotic resistant bacteria. The direct reaction has synthesized new transition metal nickel (II), copper
Senthilkumar Balakrishnan, Senbagam Duraisamy, Murugan Kasi, Selvam Kandasamy, Rajesh Sarkar, Anbarasu Kumarasamy   +5 more
doaj   +1 more source

Polyethylene glycol (PEG) decorated graphene oxide nanosheets for controlled release curcumin delivery

Heliyon, 2019
Nowadays, the use of nanostructures in various medical and biological fields such as drug delivery in cancer treatment is increasing. Among the nanostructures, graphene oxide (GO) is an excellent candidate for drug delivery application because of its ...
Jalil Charmi, Hamed Nosrati, Jafar Mostafavi Amjad, Ramin Mohammadkhani, Hosein Danafar   +4 more
doaj   +1 more source

Design, synthesis, biological evaluation and molecular docking studies of novel 3-substituted-5-[(indol-3-yl)methylene]-thiazolidine-2,4-dione derivatives

Heliyon, 2018
Various thiazolidine-2,4-dione derivatives 3a-l possessing indole moiety were designed, synthesized using appropriate conventional heating as well as microwave irradiation methods.
K. Srikanth Kumar, A. Lakshmana Rao, M.V. Basaveswara Rao   +2 more
doaj   +1 more source

QSAR study of anti-Human African Trypanosomiasis activity for 2-phenylimidazopyridines derivatives using DFT and Lipinski's descriptors

Heliyon, 2019
The quantitative structure-activity relationship (QSAR) of sixty 2-phenylimidazopyridines derivatives with anti-Human African Trypanosomiasis (anti-HAT) activity has been studied by using the density functional theory (DFT) and statistical methods. Becke'
Samir Chtita, Mounir Ghamali, Abdellah Ousaa, Adnane Aouidate, Assia Belhassan, Abdelali Idrissi Taourati, Vijay Hariram Masand, Mohammed Bouachrine, Tahar Lakhlifi   +8 more
doaj   +1 more source

Optimization of tris(2-carboxyethyl) phosphine reduction conditions for fast analysis of total biothiols in mouse serum samples

Heliyon, 2019
In this study, we investigated suitable conditions for the reduction of disulfides in mouse serum samples by tris(2-carboxyethyl) phosphine (TCEP) for fast analysis of total biothiols.
Chunfang Chang, Muneki Isokawa, Takashi Funatsu, Makoto Tsunoda   +3 more
doaj   +1 more source