Results 61 to 70 of about 303,590 (193)
A framework model for a contextualized and integrated warfarin therapy case in a master of pharmacy program [PDF]
© Copyright 2019 American Journal of Pharmaceutical Education.Objective. To develop and integrate a case study on warfarin into a clinical pharmacy workshop. Methods. A framework model was designed and used to create a case study on warfarin therapy. The
Birdi, Amandeep+2 more
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Pharmaceutical Inorganic Chemistry
Inorganic Chemistry, as a branch of chemistry, encompasses a vast and diverse range of topics,from the study of elements and their compounds to the exploration of complex coordinationcompounds, organometallics, and bioinorganic systems. This book is intended to serve as acomprehensive resource for students, researchers, and professionals who are eager ...
Dr. Tathagata Dey+3 more
openaire +2 more sources
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei+7 more
wiley +1 more source
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu+6 more
wiley +1 more source
The Changing Nature of Pharmaceutical R&D - Opportunities for Asia? [PDF]
During the 1990''s, the pharmaceutical R&D process has witnessed tremendous technological changes. The emergence of new tools like ''combinatorial chemistry'', ''high throughput screening'' and the in-creasing use of computer-aided in silico experiments ...
Mahlich ,Jörg C.+1 more
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Direct measurement of molecular mobility and crystallisation of amorphous pharmaceuticals using terahertz spectroscopy. [PDF]
Despite much effort in the area, no comprehensive understanding of the formation and behaviour of amorphous solids has yet been achieved. This severely limits the industrial application of such materials, including drug delivery where, in principle ...
core +2 more sources
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu+4 more
wiley +1 more source
Prelog\u27s Zagreb School of Organic Chemistry (1935 - 1945) [PDF]
This article on Vladimir Prelog and his contribution to the development of organic chemistry in Croatia presents data on his scientific work done in the Department of Organic Chemistry of the Technical Faculty in Zagreb, as well as the scientific ...
Rativoj Seiwerth
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An evaluation of thermodynamic models for the prediction of drug and drug-like molecule solubility in organic solvents [PDF]
Prediction of solubility of active pharmaceutical ingredients (API) in different solvents is one of the main issue for crystallization process design. Experimental determination is not always possible because of the small amount of product available in ...
Biscans, Béatrice+2 more
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Boundaries of photosynthesis: adaptations of carbon fixation in extreme environments
Photosynthesis faces challenges from environmental extremes of temperature, pH, and salinity, limiting gas diffusion, modifying membrane fluidity, and destabilizing photochemical and biochemical reactions. Photosynthetic organisms have evolved unique adaptations overcoming these stresses and maintaining their photosynthetic activity.
Pere Aguiló‐Nicolau+3 more
wiley +1 more source