Results 61 to 70 of about 1,924,905 (240)
Old School Catalog 1924-25, The School of Pharmacy [PDF]
, 1924 https://scholar.valpo.edu/oldschoolcatalogs/1001/thumbnail ...
Valparaiso University
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Similarity-based data mining in files of two-dimensional chemical structures using fingerprint measures of molecular resemblance [PDF]
, 2011 This paper reviews the use of measures of intermolecular similarity for processing databases of chemical structures, which play an important role in the discovery of new drugs by the pharmaceutical industry.
Willett, P.
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Osmotic pressure‐induced calcium response states
FEBS Open Bio, EarlyView.Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao +2 more
wiley +1 more source
, 2009 Identifying promising compounds from a vast collection of feasible compounds is an important and yet challenging problem in the pharmaceutical industry.
Mandal, Abhyuday +2 more
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Chemical Reviews, 2019 In the last few decades, pharmaceuticals, credited with saving millions of lives, have emerged as a new class of environmental contaminant. These compounds can have both chronic and acute harmful effects on natural flora and fauna.
Manvendra Patel +5 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi +5 more
wiley +1 more source
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach
FEBS Open Bio, EarlyView.This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma +10 more
wiley +1 more source
Advanced Chinese Medicine, EarlyView.Schematic representation of the study design and methodology. Abstract Ethnopharmacological relevance Jinhong tablet (JHT), a traditional Chinese patent medicine prepared from four Chinese medicinal materials, is highly effective in soothing the liver and relieving depression, regulating qi and promoting blood circulation, and regulating the stomach ...
Tingyu Zhang +12 more
wiley +1 more source
The Changing Nature of Pharmaceutical R&D - Opportunities for Asia? [PDF]
During the 1990''s, the pharmaceutical R&D process has witnessed tremendous technological changes. The emergence of new tools like ''combinatorial chemistry'', ''high throughput screening'' and the in-creasing use of computer-aided in silico experiments ...
Mahlich ,Jörg C. +1 more
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Analysis of the conformational profiles of fenamates shows route towards novel, higher accuracy, force-fields for pharmaceuticals [PDF]
, 2015 In traditional molecular mechanics force fields, intramolecular non-bonded interactions are modelled as intermolecular interactions, and the form of the torsion potential is based on the conformational profiles of small organic molecules.
Galek, P, Price, SL, Uzoh, OG
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