Results 61 to 70 of about 3,535,364 (294)
Macromolecules Applied to Pharmaceutical Chemistry
Molecules, 2005 n ...
Claudio J. Salomon
doaj +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Chemistry, Synthesis, and Structure Activity Relationship of Anticancer Quinoxalines
, 2023 Quinoxaline is a fused heterocycle system of a benzene ring and pyrazine ring. It has earned considerable attention due to its importance in the field of medicinal chemistry.
Mohamed F. Zayed
core +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Heliyon, 2016 Objectives: Microfluidic perfusion systems are used for assessing cell and tissue function while assuring cellular viability. Low perfusate flow rates, desired both for conserving reagents and for extending the number of channels and duration of ...
Austin Rountree +5 more
doaj +1 more source
Неперервна професійна освіта: теорія та практика, 2022 The relevance of the scientific topic is based on finding and solving the problems of selecting and improving the methodology of organization and conducting laboratory work in the teaching of pharmaceutical chemistry for students of the «Pharmacy ...
Galina Rizak
doaj +1 more source
Heliyon, 2020 Transferrin receptor protein 1 (TfR1) is an important molecule in anti-cancer therapy. Targeted delivery of such therapeutic compounds improves their cellular uptake and circulation time, thereby enhancing therapeutic efficacy.
Maha Ateeq AL-Refaei +2 more
doaj +1 more source
Recent Developments in the Chemistry of 3-Arylisoxazoles and 3-Aryl-2-isoxazolines
, 2017 3-Arylisoxazoles and 3-aryl-2-isoxazolines are versatile building blocks in organic chemistry. They are components of a wide number of pharmaceutical products and biologically active molecules.
VITALE, PAOLA +3 more
core +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
Salmon cartilage proteoglycan promotes the healing process of Staphylococcus aureus-infected wound
Heliyon, 2018 Wound healing is the critical event for maintaining skin function and barrier. Inflammatory state in which a variety of cells are activated and accumulated is important for wound healing.
Shouhei Hirose +3 more
doaj +1 more source