Results 61 to 70 of about 2,180,549 (342)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Bayer AG v. Housey Pharmaceuticals: Protection for Biotechnological Research Tools under Section 271(g) Found Wanting [PDF]
, 2005 [Excerpt] Research tools, a subset of biotechnological inventions protected by process patents, are “tools that scientists use in the laboratory, including cell lines, monoclonal antibodies, reagents, animal models, growth factors, combinatorial ...
Barthalow, Matthew
core +1 more source
Analysis of the conformational profiles of fenamates shows route towards novel, higher accuracy, force-fields for pharmaceuticals [PDF]
, 2015 In traditional molecular mechanics force fields, intramolecular non-bonded interactions are modelled as intermolecular interactions, and the form of the torsion potential is based on the conformational profiles of small organic molecules.
Galek, P, Price, SL, Uzoh, OG
core +1 more source
Development of illustrative materials on pharmaceutical chemistry
RUDN Journal of Medicine, 2011 The illustrative materials on pharmaceutical chemistry for the full-time students were developed. Illustrations were used while conducting distance courses on pharmaceutical chemistry.
O E Sattarova, T I Yarygina
doaj
Xanthine scaffold: scope and potential in drug development
Heliyon, 2018 Medicinal plants have been the basis for discovery of various important marketed drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine, theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
Nivedita Singh +3 more
doaj +1 more source
Anais da Academia Brasileira de Ciências, 2018 We present a comprehensive review of the advent and impact of continuous flow chemistry with regard to the synthesis of natural products and drugs, important pharmaceutical products and definitely responsible for a revolution in modern healthcare.
J. M. D. Souza +6 more
semanticscholar +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
McPherson Chemical Laboratory [PDF]
, 2006 Entry created by John H. Herrick November 22, 1976.John H. Herrick Archives: Documenting Structures at The Ohio State UniversityThe University Archives has determined that this item is of continuing value to OSU's history.McPherson Chemical Laboratory is
Herrick, John H.
core
Macromolecules Applied to Pharmaceutical Chemistry
Molecules, 2005 n ...
Claudio J. Salomon
doaj +1 more source
Flow Chemistry, Continuous Processing, and Continuous Manufacturing: A Pharmaceutical Perspective
Journal of Flow Chemistry, 2017 Flow chemistry has become a vibrant area for research over the past decade. This perspective is intended to capture insights on how these advances have and will continue to impact the development and commercialization of active pharmaceutical ingredients.
S. May
semanticscholar +1 more source