Results 31 to 40 of about 145,026 (255)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Assessing the chemical composition of natural water using analytical chemistry techniques. A case study in the orhei district, Republic of Moldova

open access: yesChemistry Journal of Moldova: General, Industrial and Ecological Chemistry
This study is primarily focused on evaluating the chemical composition of natural water in the locality of Cișmea, situated in the Orhei district, at the coordinates 47°24’56.0"N 28°45’05.9"E.
Victor Ciornea   +3 more
doaj   +1 more source

Comparison between Ultrasound- and Microwave-Assisted Extraction Methods to Determine Phenolic Compounds in Barley (Hordeum vulgare L.)

open access: yesFoods, 2023
Barley (Hordeum vulgare L.) is one of the major cereal crops worldwide. It is grown not only to be used as fodder but also for human consumption. Barley grains are a great source of phenolic compounds, which are particularly interesting for their health ...
María Álvarez-Romero   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Spectroscopic Methods for Analysis of Nano Drug Distribution System

open access: yesNano Biomedicine and Engineering, 2020
The size of the objects that are constituted within an alleged nano metric measurement of 1 to 100 nm is generally the main feature of nanoscience and nanotechnology.
Hesham Salem   +7 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Química Analítica de Processos

open access: yesQuímica Nova, 2006
Process Analytical Chemistry (PAC) is an important and growing area in analytical chemistry, that has received little attention in academic centers devoted to the gathering of knowledge and to optimization of chemical processes. PAC is an area devoted to
Trevisan Marcello G., Poppi Ronei J.
doaj   +3 more sources

Abstracts of the 1st International Online Conference on Separations

open access: yesChemistry Proceedings
The 1st International Online Conference on Separations (IOCS 2025), organized by MDPI during 15–17 October 2025, brings together researchers, professionals, and industry experts from around the world to explore the latest advancements in the dynamic ...
Grzegorz Boczkaj
doaj   +1 more source

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