Cu2+-Citrate-Chitosan Complex Nanoparticles for the Chemodynamic Therapy of Lung Cancer. [PDF]
Sun H, Zhang L, Zhao N, Xin H.
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A Copper Silicate-Based Multifunctional Nanoplatform with Glutathione Depletion and Hypoxia Relief for Synergistic Photodynamic/Chemodynamic Therapy. [PDF]
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Infection microenvironment-triggered nanoparticles eradicate MRSA by thermally amplified chemodynamic therapy and M1 macrophage. [PDF]
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Tumor Microenvironment-Responsive Magnetotactic Bacteria-Based Multi-Drug Delivery Platform for MRI-Visualized Tumor Photothermal Chemodynamic Therapy. [PDF]
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Self-assembled injectable Icariin@ Ti<sub>3</sub>C<sub>2</sub>Tx/doxorubicin hydrogel preserving osteogenesis while synergizing photodynamic and chemodynamic therapy for osteosarcoma. [PDF]
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Endoperoxide-enhanced self-assembled ROS producer as intracellular prodrugs for tumor chemotherapy and chemodynamic therapy. [PDF]
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AbstractChemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral Fenton reaction for generating highly toxic hydroxyl free radicals (•OH) to achieve selective tumor treatment. However, the limited intratumoral Fenton reaction efficiency restricts the therapeutic efficacy of CDT.
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A Forward Vision for Chemodynamic Therapy: Issues and Opportunities
Angewandte Chemie International Edition, 2023AbstractSince the insight to fuse Fenton chemistry and nanomedicine into cancer therapy, great signs of progress have been made in the field of chemodynamic therapy (CDT). However, the exact mechanism of CDT is obscured by the unique tumor chemical environment and inevitable nanoparticle‐cell interactions, thus impeding further development.
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Nanocatalyst‐Mediated Chemodynamic Tumor Therapy
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Nanotechnology-enabled Chemodynamic Therapy and Immunotherapy
Current Cancer Drug Targets, 2021High-level reactive oxygen species (ROS) have been reported to exert a robust anti-tumor effect by inducing cell apoptosis or necroptosis. Based on the Fenton reaction or Fenton-like reaction, a therapeutic strategy (i.e., chemodynamic therapy (CDT)) is proposed, where hydroxyl radicals (·OH) are one of the ROS that can be produced to kill tumors via ...
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