Single-atom nanozyme-mediated dihydroartemisinin delivery for self-enhanced chemodynamic therapy and ferroptosis [PDF]
Materials Today BioChemodynamic therapy (CDT), leveraging intracellular iron ions (Fe2+) and hydrogen peroxide (H2O2), is a highly selective therapeutic strategy with significant potential.
Yuanlong Zhang +7 more
doaj +2 more sources
Nanosystems for chemodynamic based combination therapy: Strategies and recent advances
Frontiers in Pharmacology, 2022 Chemodynamic therapy (CDT), a newly developed approach for cancer treatment, can convert hydrogen peroxide (H2O2) into toxic hydroxyl radicals (•OH) by using Fenton/Fenton-like reaction to kill tumor cells.
Minghui Li +6 more
doaj +1 more source
Recent advances in Fenton and Fenton-like reaction mediated nanoparticle in cancer therapy [PDF]
, 2023 Fenton and Fenton like reaction have been well clarified as efficient reactive oxygen species (ROS) sources in tumor, and have been widely developed into a cancer treatment method.
Han, Huijie +2 more
core +1 more source
Mitochondria-Targeting Chemodynamic Therapy Nanodrugs for Cancer Treatment
Frontiers in Pharmacology, 2022 Mitochondria, as one of the most critical subcellular organelles of cancer cells, are very vulnerable and often on the verge of oxidative stress. The classic chemodynamic therapy (CDT) directly employs endogenous chemical energy to trigger reactive ...
Qiaohui Chen +19 more
doaj +1 more source
Co-Loading of Inorganic Nanoparticles and Natural Oil in the Electrospun Janus Nanofibers for a Synergetic Antibacterial Effect [PDF]
, 2022 Side-by-side electrospinning is a powerful but challenging technology that can be used to prepare Janus nanofibers for various applications. In this work, cellulose acetate (CA) and polycaprolactone (PCL) were used as polymer carriers for silver ...
Bligh, Sim Wan Annie +3 more
core +1 more source
Molecules, 2021 Chemodynamic therapy (CDT) based on intracellular Fenton reactions is attracting increasing interest in cancer treatment. A simple and novel method to regulate the tumor microenvironment for improved CDT with satisfactory effectiveness is urgently needed.
Peng Zhu +8 more
doaj +1 more source
Cu^{2+}-Chelating Mesoporous Silica Nanoparticles for Synergistic Chemotherapy/Chemodynamic Therapy [PDF]
, 2022 In this study, a pH-responsive controlled-release mesoporous silica nanoparticle (MSN) formulation was developed. The MSNs were functionalized with a histidine (His)-tagged targeting peptide (B3int) through an amide bond, and loaded with an anticancer ...
Chen, Wenling +8 more
core +1 more source
A bimetallic nanocatalyst for light-free oxygen sensitization therapy
Cell Reports Physical Science, 2021 Summary: Singlet oxygen (1O2) is extensively employed by reactive oxygen species (ROS)-based cancer therapies, such as photodynamic therapy (PDT) and chemodynamic therapy (CDT).
Xia Guo +13 more
doaj +1 more source
Injectable, antibacterial, and oxygen-releasing chitosan-based hydrogel for multimodal healing of bacteria-infected wounds [PDF]
, 2023 Bacterial infection is one of the main challenges of wound healing. It imposes financial and healthcare costs. The emergence of antibiotic-resistant bacteria has increased concerns about this challenge, and made finding alternative solutions a crucial ...
Bochani, Shayesteh +7 more
core +3 more sources
Rational Design of a Gd(III)–Cu(II) Nanobooster for Chemodynamic Therapy Against Cancer Cells
Frontiers in Chemistry, 2022 Copper (II) containing coordination complexes have attracted much attention for chemodynamic therapy (CDT) against cancer cells. In this study, the bimetallic nanobooster [Gd2Cu(L)2(H2O)10]·6H2O was prepared by a solvothermal method based on tetrazole ...
Xin-Ya Shi +8 more
doaj +1 more source