Results 31 to 40 of about 2,610 (179)

Mitochondria-Targeted Nanomedicine for Enhanced Efficacy of Cancer Therapy [PDF]

, 2021
Nanomedicines have been designed and developed to deliver anticancer drugs or exert anticancer therapy more selectively to tumor sites. Recent investigations have gone beyond delivering drugs to tumor tissues or cells, but to intracellular compartments ...
Gao, Yan, Huang, Di, Li, Jiachen, Li, Jialiang, Shi, Jisen, Tong, Haibei, Xia, Bing   +6 more
core   +2 more sources

Metal ion-zeolite nanomaterials for chemodynamic therapy [PDF]

, 2021
A new therapeutic approach called chemodynamic therapy (CDT), which can be defined as specific OH generation in cancer cells via Fenton reactions, was recently proposed.1 The advantages of CDT can be ascribed to the higher specificity, no external field ...
Almeida Aguiar, Cristina, Baltazar, F., Bertão, A. R., Carvalho, V. M. C, Ferreira, S. D. C., Fonseca, António, Neves, Isabel C., Oliveira, R. D., Rodrigues, F. C.   +8 more
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Metal-Polymer Nanoconjugates Application in Cancer Imaging and Therapy [PDF]

, 2022
Metallic-based nanoparticles present a unique set of physicochemical properties that support their application in different fields, such as electronics, medical diagnostics, and therapeutics.
Correia, I.J., Diogo, Duarte de Melo, Fernandes, Natanael, Figueiredo, André Q., Moreira, André, Rodrigues, Ana Carolina Félix   +5 more
core   +1 more source

Self-Assembly Iron Oxide Nanoclusters for Photothermal-Mediated Synergistic Chemo/Chemodynamic Therapy

Journal of Immunology Research, 2021
Background and Purpose. Although chemodynamic therapy (CDT) is promising for cancer treatment, its clinical application is still limited because of unresolved issues. In this study, an efficient CDT agent for synergistic chemo/CDT therapy mediated by the
Xiang Li, Zhen Wang, Mian Ma, Zhouqing Chen, Xiang-long Tang, Zhong Wang   +5 more
doaj   +1 more source

An Injectable Hydrogel for Enhanced FeGA-Based Chemodynamic Therapy by Increasing Intracellular Acidity

Frontiers in Oncology, 2021
Hydroxyl radical (•OH)-mediated chemodynamic therapy (CDT) is an emerging antitumor strategy, however, acid deficiency in the tumor microenvironment (TME) hampers its efficacy.
Wen Zeng, Wen Zeng, Dazhen Jiang, Zeming Liu, Weilong Suo, Ziqi Wang, Daoming Zhu, Qinqin Huang   +7 more
doaj   +1 more source

Injectable Antibacterial Gelatin-Based Hydrogel Incorporated with Two-Dimensional Nanosheets for Multimodal Healing of Bacteria-Infected Wounds [PDF]

, 2022
The design and development of multifunctional injectable hydrogels with high photothermal antibacterial activity and shape adaptability to accelerate bacteria-infected wound healing is of critical importance in clinical applications.
Alinezhad, Vajihe, Bagheri, Hadi, Bochani, Shayesteh, Guo, Baolin, Haghi, Fakhri, Hirata, Ikue, Kalantari-Hesari, Ali, Makvandi, Pooyan, Maleki, Aziz, Mattoli, Virgilio, Salimi, Abdollah, Shahbazi, Mohammad Ali   +11 more
core   +1 more source

A core-shell Au@Cu2-xSe heterogeneous metal nanocomposite for photoacoustic and computed tomography dual-imaging-guided photothermal boosted chemodynamic therapy

Journal of Nanobiotechnology, 2021
Chemodynamic therapy (CDT) has aroused extensive attention for conquering cancers because of its high specificity and low invasiveness. Quick generation of hydroxyl radicals (·OH) during CDT could induce more irreparable damage to cancer cells.
Le Zhang, Chunjuan Jiang, Bing Li, Zhengwang Liu, Bingxin Gu, Simin He, Panli Li, Yun Sun, Shaoli Song   +8 more
doaj   +1 more source

GSH-responsive sequential mitochondria-targeting nanoagents for photothermal-enhanced chemodynamic therapy

Materials & Design, 2022
Mitochondria-targeting nanoparticles have proven to be promising platforms for cancer therapy. However, precise mitochondria targeting in the complex tumor environment is still challenging and requires more ingenious design.
Huaming He, Fang Zhao, Wukun Zhong, Yuling Yang, Yuhong Lin, Yihang Ding, Jiajia Yang, Chunhua Lu, Xiankun Tu   +8 more
doaj   +1 more source

Implantable composite fibres with Self-supplied H2O2 for localized chemodynamic therapy [PDF]

, 2020
The anticancer efficacy of chemodynamic therapy (CDT) is considerably restrained by the inadequate content of H2O2 within tumor microenvironment (TME), unexpected oxidation of Fenton agents and low targeting efficiency of particulate therapeutic ...
Fu, Y, Gao, J, Han, G, Huang, J, Li, X, Ren, Z, Wang, G   +6 more
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Construction of iron-mineralized black phosphorene nanosheet to combinate chemodynamic therapy and photothermal therapy

Drug Delivery, 2022
Chemodynamic therapy (CDT) by triggering Fenton reaction or Fenton-like reaction to generate hazardous hydroxyl radical (•OH), is a promising strategy to selectively inhibit tumors with higher H2O2 levels and relatively acidic microenvironment.
Zhaoqing Shi, Jing Tang, Chuchu Lin, Ting Chen, Fan Zhang, Yuxing Huang, Ping Luan, Zhuo Xin, Qianqian Li, Lin Mei   +9 more
doaj   +1 more source