Results 51 to 60 of about 2,610 (179)

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Therapeutic Frontiers in Nanozyme-Based Cancer Treatment: Advances, Challenges, and Future Directions [PDF]

Nanozymes, artificial nanomaterials mimicking enzyme activity, are at the forefront of innovative cancer therapies, particularly in chemodynamic therapy (CDT), photodynamic therapy (PDT), and photothermal therapy (PTT).
A.I. Kuruppu, D.M. Silva
core   +2 more sources

Multicomponent Transition Metal Dichalcogenide Nanosheets for Imaging‐Guided Photothermal and Chemodynamic Therapy [PDF]

, 2020
Transition metal dichalcogenides (TMDs) have received considerable attention due to their strong absorption in the near‐infrared (NIR) region, strong spin‐orbit coupling, and excellent photothermal conversion efficiency (PCE).
Fu, L, Liang, R, Wang, H, Wang, Y, Wei, M, Weng, X, Williams, GR, Wu, J, Zhu, Y   +8 more
core  

Dendrimer‐Based Nanodrugs for Chemodynamic Therapy of Tumors

Advanced NanoBiomed Research
To realize precise tumor treatment, chemodynamic therapy (CDT) that utilizes metal element to trigger Fenton or Fenton‐like reaction to generate cytotoxic hydroxyl radicals in tumor region has been widely investigated.
Caiyun Zhang, Yunqi Guo, Mingwu Shen, Xiangyang Shi   +3 more
doaj   +1 more source

Ternary NiCoTi-layered double hydroxide nanosheets as a pH-responsive nanoagent for photodynamic/chemodynamic synergistic therapy

Fundamental Research
Combining photodynamic therapy (PDT) with chemodynamic therapy (CDT) has been proven to be a promising strategy to improve the treatment efficiency of cancer, because of the synergistic therapeutic effect arising between the two modalities.
Tingting Hu, Zhan Zhou, Jiajia Zha, Gareth R. Williams, Zhikang Wu, Wei Zhao, Weicheng Shen, Hai Li, Xisheng Weng, Ruizheng Liang, Chaoliang Tan   +10 more
doaj   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

Chemodynamic nanomaterials for cancer theranostics

Journal of Nanobiotechnology, 2021
It is of utmost urgency to achieve effective and safe anticancer treatment with the increasing mortality rate of cancer. Novel anticancer drugs and strategies need to be designed for enhanced therapeutic efficacy.
Jingqi Xin, Caiting Deng, Omer Aras, Mengjiao Zhou, Chunsheng Wu, Feifei An   +5 more
doaj   +1 more source

Copper nitroprusside: An innovative approach for targeted cancer therapy via ROS modulation [PDF]

The clinical application of nanomaterials for chemodynamic therapy (CDT), which generate multiple reactive oxygen species (ROS), presents significant challenges.
Adeel, Muhammad, Asif, Kanwal, Bartoletti, Michele, Brezar, Simona Kranjc, Caligiuri, Isabella, Canzonieri, Vincenzo, Cemazar, Maja, Mahbubur Rahman, Md, Rizzolio, Flavio   +8 more
core   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Tumor-Targeted Conjugated Polymer Nanoparticles with Encapsulated Iron and Its Biomedical Application for In Vitro Killing of Melanoma Cell Lines Through Ferroptosis Assisted Chemodynamic Therapy (CDT) [PDF]

, 2019
Melanoma represents one of the most aggressive and lethal forms of skin cancer, with annually rising incidences throughout the world. Although chemotherapy modalities remain the mainstay of treatment, the therapeutic potential of chemotherapy typically ...
Jasim, Khalaf
core   +1 more source