Results 41 to 50 of about 2,610 (179)

Recent advances in nanomaterial-based drug delivery systems for melanoma therapy [PDF]

, 2023
Background and Purpose Safe and effective drug delivery is crucial for the treatment of cancer, which is quite impossible to achieve through traditional methods.
Jena, Goutam Kumar, Kaishap, Partha Pratim, Parhi, Rabinarayan   +2 more
core   +2 more sources

Manganese-containing polydopamine nanoparticles as theranostic agents for magnetic resonance imaging and photothermal/chemodynamic combined ferroptosis therapy treating gastric cancer

Drug Delivery, 2022
Gastric cancer (GC) is a serious disease with high morbidity and mortality rates worldwide. Chemotherapy plays a key role in GC treatment, while inevitable drug resistance and systematic side effects hinder its clinical application.
Zhian Chen, Zhenhao Li, Chuangji Li, Huilin Huang, Yingxin Ren, Zhenyuan Li, Yanfeng Hu, Weihong Guo   +7 more
doaj   +1 more source

Immunogenic sonodynamic therapy for inducing immunogenic cell death and activating antitumor immunity [PDF]

, 2023
Immunotherapy is widely regarded as a promising treatment for cancer. However, the immune effector phase suppression of tumor microenvironment (TME) and the generation of immune-related adverse events limit its application.
Meng Du, Meng Du, Ting Wang, Ting Wang, Wangrui Peng, Wangrui Peng, Zhiyi Chen, Zhiyi Chen, Zhiyi Chen   +8 more
core   +1 more source

Copperphosphotungstate Doped Polyanilines Nanorods for GSH-Depletion Enhanced Chemodynamic/NIR-II Photothermal Synergistic Therapy

International Journal of Nanomedicine, 2023
Sheng Ye,1 Huichun Xiao,1 Jian Chen,1 Di Zhang,1 Li Qi,1 Ting Peng,2 Yanyang Gao,2 Qianbing Zhang,3 Jinqing Qu,2 Lei Wang,4 Ruiyuan Liu1 1Guangdong Provincial Key Laboratory of Medical Image Processing, School of Biomedical Engineering, Southern Medical ...
Ye S, Xiao H, Chen J, Zhang D, Qi L, Peng T, Gao Y, Zhang Q, Qu J, Wang L, Liu R   +10 more
doaj  

An in situ self-assembled peptide derivative for inhibition of glutathione synthesis and selective enhancement of tumor radiotherapy [PDF]

, 2023
Background: Inhibition of glutathione (GSH) synthesis in cancer cells considerably improves the efficacy of reactive oxygen species (ROS)-related tumor therapy.
Cai, Xiaoyao, Cui, Benhang, Gao, Jie, Gao, Yang, Gong, Xinyan, Li, Paiyun, Wang, Hang, Yang, Cuihong, Zhang, Wenxue   +8 more
core   +1 more source

Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis

Advanced Science, EarlyView.
Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren, Xuewei Wang, Panpan Li, Hao Wu, Zhifei Bi, Qi Gao, Bolong Ma, Zixuan Tian, Jianfei Liu, Fuqiang Feng, Wen Liu, Lin Li, Chengwu Zhang   +12 more
wiley   +1 more source

In Situ Redox of TiSe2 Nanoplates to Excite Chemodynamic‐Enhanced Cancer Sono‐Immunotherapy

Small Structures
Different from the direct delivery of chemodynamic agents into tumor tissue for chemodynamic therapy (CDT), this work reports the fabrication of heterojunction sonosensitizers (CD/TiSe2) for the in situ generation of chemodynamic agents by responding to ...
Xialing He, Jinming Cai, Jinyan Hu, Zhenlin Zhang, Xue Bai, Shan Zhang, Dengyu Pan, Jinliang Liu, Bijiang Geng   +8 more
doaj   +1 more source

Albumin-Stabilized Manganese Oxide/Semiconducting Polymer Nanocomposites for Photothermal-Chemodynamic Therapy of Hepatic Carcinoma

Frontiers in Bioengineering and Biotechnology, 2022
Hepatic carcinoma is one of the most common cancers worldwide, while its treatment remains a great challenge. Traditional therapeutic methods often have disadvantages such as limited therapeutic efficacy and potential side effects.
Qi Su, Changcun Liu, Jingyi Zhu, Mengbin Ding, Zhen Zhang, Jingchao Li, Qin Zhang   +6 more
doaj   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

CRISPR/Cas9‐Based Vanadium MXene‐Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal‐Induced Multi‐Effect Synergistic Antitumor Therapy

Advanced Science, EarlyView.
In this study, a MXene‐based V4C3 nanoplatform, VARH, was constructed, which achieved a photothermal conversion efficiency of 44.21% in the NIR‐II window. This platform integrated photothermal therapy, chemodynamic therapy, and thermodynamic therapy with CRISPR/Cas9‐mediated heat shock protein 90 knock‐out technology.
Zi‐Jian Huang, Feng‐Ming Li, Yi‐Fan Tu, Ke‐Ke Feng, Cheng‐Lei Li, Shi‐Cheng Tian, Yong‐Shan Hu, Jing‐Wei Shao, Zhen‐Hua Liu   +8 more
wiley   +1 more source