Results 231 to 240 of about 189,065 (308)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, Volume 16, Issue 7, Page 1244-1258, July 2026.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

The Innate and Adaptive Immune Functions of Osteoblast-Lineage Cells. [PDF]

Curr Osteoporos Rep
Hossain MA, Hurtado PR, Atkins GJ.
europepmc   +1 more source

Natural History of Chronic Kidney Disease in Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley   +1 more source

CXCR3 signaling promotes Delta One T cell recruitment and antitumor efficacy in colorectal cancer. [PDF]

J Immunother Cancer
Carreira M, Barros L, Cruz RM, Ferreira C, Costa C, Ferreira CM, Mensurado S, Silva-Santos B, Blanco-Domínguez R.   +8 more
europepmc   +1 more source

Inflammation profiles in Alzheimer's disease relate to cognition and neurodegeneration

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Immune signaling alterations have been implicated in Alzheimer's disease (AD) pathophysiology, but their heterogeneity across the disease continuum in real‐world cohorts is poorly characterized, limiting the development of stratified immunomodulatory approaches.
Katherine R. Birditt, Kalliopi Mavromati, Peter Swann, Terence Quinn, Atticus H. Hainsworth, Lynne Hughes, John T. O'Brien, William McEwan, Maura Malpetti   +8 more
wiley   +1 more source

Integrative Multi‐Omics Analysis Reveals the Tumor‐Suppressive and Immunoregulatory Roles of SEMA5B in Prostate Cancer

BioFactors, Volume 52, Issue 4, July/August 2026.
This study identifies SEMA5B as a tumor suppressor in prostate cancer that suppresses the malignant phenotype, affects mitochondrial oxidative metabolism, induces cell cycle arrest and apoptosis, and is associated with the immune‐inflammatory tumor microenvironment, highlighting its potential as a biomarker and target for immunotherapy. ABSTRACT SEMA5B
Zhiguo Fan, Yihaoyun Lou, Xuan Zhou, Guang Liu, Xiaomin Zhang, Yuanjie Tang, Zhen Zhu, Shancheng Ren, Yifan Chang   +8 more
wiley   +1 more source

Restriction of HSV-1 replication by Pistacia vera L. extracts reveals a promising strategy for regulating virus-mediated chemokine response in monocytic cells. [PDF]

Sci Rep
Pennisi R, Costa M, Tamburello MP, Trischitta P, Mandalari G, Sciortino MT.   +5 more
europepmc   +1 more source

Comparative Transcriptomic Profiling Reveals Differences in Initiation of Antiviral Response in Low rAAV Producing HEK293 Suspension Cells

Biotechnology Journal, Volume 21, Issue 7, July 2026.
Graphical Abstract and Lay Summary Comparative, time‐resolved transcriptomic profiling of HEK293 producer cell lines identified differences in antiviral signaling and cell cycle regulation between producer phenotypes. Low‐producer exhibited strong interferon‐mediated antiviral responses that may restrict vector production, whereas high‐producers showed
Georg Smesnik, Nikolaus Virgolini, Astrid Dürauer, Nicole Borth   +3 more
wiley   +1 more source

Serum Levels of Selected Chemokines in Patients with Systemic Lupus Erythematosus Correlate with Disease Activity and Clinical Features: Results from a Single-Center Observational Study. [PDF]

Biomedicines
Dziedzic R, Siwiec-Koźlik A, Koźlik-Siwiec P, Węglarczyk K, Siedlar M, Korkosz M, Kosałka-Węgiel J.   +6 more
europepmc   +1 more source

Japanese Encephalitis Virus and Host Innate Immunity: Insights Into TLR Signaling, PRR Crosstalk, and Viral Immune Evasion

Cell Biochemistry and Function, Volume 44, Issue 7, July 2026.
ABSTRACT Japanese encephalitis virus (JEV), a neurotropic flavivirus and a major cause of viral encephalitis, poses a significant global health threat due to its neuroinvasive potential. Host innate immune responses, particularly those mediated by pattern‐recognition receptors such as Toll‐like receptors (TLRs) and RIG‐I–like receptors, play critical ...
Mohammad Enamul Hoque Kayesh, Michinori Kohara, Kyoko Tsukiyama‐Kohara   +2 more
wiley   +1 more source