Results 91 to 100 of about 133,417 (336)

CHEMORADIOTHERAPY FOR BRAIN TUMORS

, 2022
Among malignant brain tumors, glioblastoma is the most common. This is an exceptionally aggressive and locally spreading tumor with a very poor prognosis and low survival rate. Glioma is considered resistant to chemotherapy and radiation. Recently, concomitant and adjuvant chemoradiotherapy with temozolomide has become the standard treatment method for
openaire   +1 more source

Prolonged Prophylactic Antibiotics Based on Preoperative Bile Culture Reduce Surgical Site Infections After Pancreaticoduodenectomy Following Preoperative Biliary Drainage: A Propensity‐Matched Analysis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Objective The optimum duration of prophylactic antibiotics after pancreaticoduodenectomy following preoperative biliary drainage to prevent surgical site infections remains controversial. We evaluate whether a prolonged course of prophylactic antibiotics reduces surgical site infection after pancreaticoduodenectomy following biliary drainage ...
Kyohei Matsumoto, Atsushi Shimizu, Yuji Kitahata, Akihiro Takeuchi, Hideki Motobayashi, Masatoshi Sato, Tomohiro Yoshimura, Shinya Hayami, Atsushi Miyamoto, Manabu Kawai   +9 more
wiley   +1 more source

MAP17 (PDZK1IP1) and pH2AX are potential predictive biomarkers for rectal cancer treatment efficacy [PDF]

, 2018
Rectal cancer represents approximately 10% of cancers worldwide. Preoperative chemoradiotherapy increases complete pathologic response and local control, although it offers a poor advantage in survivorship and sphincter saving compared with that of ...
Carnero, Amancio, Espinosa-Sánchez, Asunción, Felipe-Abrio, Blanca, Fernández-Fernández, María Carmen, Muñoz-Galván, Sandra, Ortiz, María José, Peinado-Serrano, Javier, Rivero, María, Suarez-Martinez, Elisa   +8 more
core   +1 more source

Dynamic changes of bone microarchitecture and volumetric mineral density assessed by HR-pQCT in patients with cervical cancer after concurrent chemoradiotherapy: a prospective study

Biomarker Research
Bone changes in patients undergoing pelvic radiotherapy remain unclear. This study initially utilized high-resolution peripheral quantitative computed tomography (HR-pQCT) to assess the dynamic changes in bone microarchitecture and volumetric bone ...
Weishi Cheng, Yijun Wu, Jing Shen, Hui Guan, Li Zhang, Hongnan Zhen, Yinjie Tao, Weibo Xia, Zhikai Liu, Fuquan Zhang   +9 more
doaj   +1 more source

The updated network meta-analysis of the therapeutic efficacies of lung cancer: A systematic review and meta-analysis

Tzu Chi Medical Journal
Objectives: Lung cancer is one of the most common malignancies worldwide. We aim to investigate the most effective treatments for advanced/nonadvanced stages of lung cancer patients.
Chuan-Hsin Chang, Chih-Cheng Chien, Yue-Cune Chang   +2 more
doaj   +1 more source

Integrating Immune Checkpoint Inhibitors With Total Neoadjuvant Therapy in Proficient Mismatch Repair Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
The key to unlocking ICI benefit in pMMR/MSS LARC is to convert “cold” tumors into “hot” ones through lymphocyte‐sparing SCRT and judicious chemotherapy, creating a milieu in which ICIs can act effectively. ABSTRACT The management of locally advanced rectal cancer (LARC) has evolved with the adoption of total neoadjuvant therapy (TNT), integrated ...
Yoshinori Kagawa, Jun Watanabe, Koji Ando, Caleah Kitchens, Aron Bercz, J. Joshua Smith   +5 more
wiley   +1 more source

Adjuvant Second-Dose Chemotherapy before Surgery for Patients with Locally Advanced Rectal Malignancy Is Not Beneficial: A Systematic Review and Meta-Analysis

Gastroenterology Research and Practice, 2017
Background. Preoperative chemoradiotherapy is the standard treatment for patients with locally advanced rectal cancer, although tumor responses vary widely; some patients may achieve a pathologic complete response rate (pCR) after chemoradiotherapy ...
Min Chen, Xue Song, Liang-zhou Chen, Lin Xu, Yi-pu Lu, Jin-song Zhang   +5 more
doaj   +1 more source

The effects of chemoradiotherapy on recurrence and survival in locally advanced rectal cancers with curative total mesorectal excision: a prospective, nonrandomized study

World Journal of Surgical Oncology, 2017
Background There are only two prospective, randomized studies comparing preoperative long-term chemoradiotherapy and postoperative chemoradiotherapy in locally advanced rectal cancer (LARC); however, conflicting results in terms of locoregional ...
Erhan Akgun, Serdar Ozkok, Mevlut Tekin, Tayfun Yoldas, Cemil Caliskan, Timur Kose, Bulent Karabulut, Murat Sezak, Nevra Elmas, Omer Ozutemiz   +9 more
doaj   +1 more source

Learning Curve Effect in Reducing Local Recurrence Rate After Resection of Pancreatic Cancer With Arterial Abutment: A Single‐Center Retrospective Study

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) with arterial abutment is a complex, high‐risk surgery. We aimed to investigate the clinicopathological features, risk factors, and learning curve for local recurrence after pancreatectomy for PDAC with arterial abutment.
Jun Ishida, Hirochika Toyama, Takayuki Kodama, Yoshihide Nanno, Takuya Mizumoto, Shohei Komatsu, Hiroaki Yanagimoto, Masahiro Kido, Tomoo Ito, Takumi Fukumoto   +9 more
wiley   +1 more source

Interventions for the treatment of oral cavity and oropharyngeal cancer:chemotherapy [PDF]

, 2010
<b>Background:</b> Oral cavity and oropharyngeal cancers are frequently described as part of a group of oral cancers or head and neck cancer. Treatment of oral cavity cancer is generally surgery followed by radiotherapy, whereas oropharyngeal
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core   +9 more sources