Results 81 to 90 of about 93,945 (299)

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source

Immune-related gene signature improves prognosis prediction in patients with breast cancer and associates it with tumor immunity and inflammatory response

BMC Women's Health
Background The prognostic potential of immune-related genes, particularly immune checkpoint inhibitors (ICIs) and long non-coding RNAs (lncRNAs), is gaining attention for evaluating the prognosis of breast cancer patients. Methods We analyzed 23 datasets
Haiping Zhang, Lu Sun, Jingjing Liu, Jing Wang, Lingchao Meng, Yuan Gao, Jingwu Li, Qi Zhou   +7 more
doaj   +1 more source

Direct Effects of Chemoradiotherapy following Esophagectomy

, 2011
<i>Background:</i> Esophageal cancer is a major cause of morbidity and mortality, but despite continuing research, few effective therapies have been identified.
V. Juhasz, T. Koszegi, L. Bogar, S. Marton, A. Papp, L. Cseke, P.O. Horvath, S. Ghosh   +7 more
core   +1 more source

“It's the Exact Same Treatment … Except Only 5 Min Away”: A RE‐AIM Evaluation of a Speech‐Language Pathology Shared‐Care Model for Rural Patients With Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Challenges accessing post‐treatment speech‐language pathology (SLP) services can add to treatment burden for rural patients with head and neck cancer (HNC). Hence, the aim of this study was to evaluate a shared‐care SLP service designed to support local SLP access for patients with HNC, using the RE‐AIM framework.
Corey Patterson, Elizabeth C. Ward, Rebecca L. Packer, Jasmine Foley, Laurelie R. Wishart, Clare L. Burns, Sally Pether, Wendy Comben   +7 more
wiley   +1 more source

Long-term bowel functional outcomes following anal sphincter-preserving surgery for upper and middle rectal cancer: a single-center longitudinal study [PDF]

Annals of Coloproctology
Purpose Despite advances in neoadjuvant chemoradiotherapy and anal sphincter-preserving surgery for rectal cancer, bowel dysfunction is still unavoidable and negatively affects patients’ quality of life.
Ahmad Sakr, Seung Yoon Yang, Min Soo Cho, Hyuk Hur, Byung Soh Min, Kang Young Lee, Nam Kyu Kim   +6 more
doaj   +1 more source

Safe Omission of Postoperative Neck Irradiation in Selected pN0 Patients With Locally Advanced Oral Cavity Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Postoperative radiotherapy is the standard treatment for locally advanced oral squamous cell carcinoma (OSCC); however, the indication for neck irradiation (NI) in pN0 patients remains debatable. We evaluated whether the omission of NI compromises outcomes in pT3–T4 pN0 patients treated with adequate neck dissection (ND).
Mathilde Mirallié, Anouchka Modesto, Marie Pajiep, Sébastien Vergez, Jérôme Sarini, Lucie Piram, Céline Dalmasso, Benjamin Vairel, Emilien Chabrillac, Agnès Dupret‐Bories   +9 more
wiley   +1 more source

Survival benefit of combined immunotherapy and chemoradiotherapy in locally advanced unresectable esophageal cancer: an analysis based on the SEER database

Frontiers in Immunology
BackgroundWhile simultaneous chemoradiotherapy remains the established therapeutic modality for patients afflicted with locally advanced esophageal cancer, the effectiveness of this radical approach falls short of the desired outcome.
Liangyun Xie, Liangyun Xie, Zhi Zhang
doaj   +1 more source

Treatment Regimens for Adjuvant Chemoradiotherapy Cohort.

, 2016
Treatment Regimens for Adjuvant Chemoradiotherapy Cohort.
Vishal Gupta (763297), Brett A. Miles (3387800), Marshall Posner (3387791), Eric M. Genden (155320), Krzysztof J. Misiukiewicz (3387794), Jerry Liu (2658601), William Su (3387797), Richard L. Bakst (317552)   +7 more
core   +1 more source

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19‐09, CONPELAN Study

Head &Neck, EarlyView.
ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun, Seyoung Seo, Jang Ho Cho, Keon‐Uk Park, Sang‐Cheol Lee, Yong Won Choi, Tak Yun, Seong Hoon Shin, Sung‐Bae Kim, Seungeun Lee, Chang Ho Ahn, Bhumsuk Keam   +11 more
wiley   +1 more source

From Nodal Metastasis to Oncologic Recurrence in Tongue and Oral Floor Squamous Cell Carcinoma: Distinct Failure Patterns and Clinicopathological Risk Profiles

Head &Neck, EarlyView.
ABSTRACT Background Locoregional recurrence remains a clinically relevant problem in oral squamous cell carcinoma (OSCC). Whether local, ipsilateral nodal, and contralateral nodal failure represent distinct disease processes with different clinicopathological associations has not been systematically evaluated.
Jannik Ketschau, Jonathan Mohr, Alex Grabenhorst, Hannes Singer, Helena Kram, Cornelius Leopold, Nils Krautkremer, Katharina Pippich, Klaus‐Dietrich Wolff, Lucas M. Ritschl   +9 more
wiley   +1 more source