Results 61 to 70 of about 97,795 (300)

Adjuvant anti-TIGIT plus anti-PD-1 in melanoma: A necessary failure that clarifies the path forward

Translational Oncology
The phase 3 KEYVIBE-010 trial investigated adjuvant vibostolimab (anti-TIGIT) plus pembrolizumab versus pembrolizumab alone in resected stage IIB–IV melanoma.
Qinghua Ke, Shiqiong Zhou
doaj   +1 more source

The impact of long‐course chemoradiotherapy on the myenteric plexus, neuromuscular functions and responses to prokinetic drugs in the human rectum [PDF]

BACKGROUND & AIMS: The long-term effects of chemoradiotherapy on human rectum are poorly understood. The aims were to investigate changes in inflammatory status, myenteric neuron numbers/phenotype, neuromuscular functions and prokinetic drug efficacy ...
Knowles, CH, Makwana, R, Thaha, M, Broad, J, Elahi, S, Palmer, A, Baidoo, N, Kung, VWS, Chin-Aleong, J, Epton, S, Sanger, GJ, Makwana, R., Knowles, C., Makwana, Raj, Broad, John; id_orcid, Kung, Victor W.S., Sanger, G., Palmer, A., Palmer, Alexandra, Epton, Sarah, Elahi, Shezan, Sanger, Gareth J., Broad, J., Kung, V., Elahi, S., Baidoo, N., Knowles, Charles H., Chin-Aleong, Joanne, Thaha, Mohamed, Baidoo, Nicholas, Thaha, M., Chin‐Aleong, Joanne   +31 more
core   +1 more source

Impact of Postoperative Infectious Complications on Long‐Term Survival After Curative Resection for Colorectal Cancer: A Multicenter Study in the Minimally Invasive Era

Annals of Gastroenterological Surgery, EarlyView.
Postoperative infectious complications (PICs) have been associated with poor long‐term outcomes after colorectal cancer surgery, but evidence in the modern minimally invasive era remains limited. In this multicenter cohort of 5377 patients undergoing curative resection, PICs were independently associated with worse overall survival and relapse‐free ...
Takehito Yamamoto, Ryosuke Mizuno, Yoshiro Itatani, Tetsuya Shiota, Masahiro Yamada, Tadayoshi Yamaura, Mami Yoshitomi, Kazutaka Obama   +7 more
wiley   +1 more source

Paradigms in chemoradiotherapy

European Journal of Cancer Supplements, 2007
Abstract The efficacy of radiation in locally advanced non- small cell lung cancer (NSCLC) is limited. In a search for improving the outcome, particular attention has focused on the possibility of combining radi- ation with chemotherapy. The two most frequently used combined modality strategies include induction chemotherapy (chemotherapy preceding ...
openaire   +2 more sources

Forest plot of efficacy comparing chemoradiotherapy (CRT) with chemotherapy (CT).

, 2013
Forest plot of efficacy comparing chemoradiotherapy (CRT) with chemotherapy (CT).
Yan-Xian Chen (434843), De-Rong Xie (5655775), Ying Wei (214901), Bei Zhang (428038), Yuan-Yuan Huang (2076643), Si-Wei Zhou (5655772), Qiong Yang (28822)   +6 more
core   +1 more source

Prognostic Impact of Circumferential Resection Margin in Minimally Invasive Surgery for Locally Advanced Rectal Cancer: A Multicenter Prospective Study

Annals of Gastroenterological Surgery, EarlyView.
This multicenter prospective study provides the first Japanese evidence that circumferential resection margin positivity after minimally invasive surgery is associated with poorer long‐term outcomes in locally advanced rectal cancer. As the cohort predominantly included patients treated with upfront surgery, these findings provide important evidence to
Atsushi Hamabe, Masaaki Ito, Shigeo Toda, Yusuke Suwa, Suguru Hasegawa, Masanori Kotake, Masafumi Inomata, Kazuki Ueda, Atsushi Ogura, Kiichi Sugimoto, Kei Kimura, Koki Otsuka, Tatsuki Noguchi, Koya Hida, Yasumitsu Hirano, Kazushige Kawai, Shigeru Yamagishi, Takeshi Naitoh, Ichiro Takemasa, on behalf of Japan Society of Laparoscopic Colorectal Surgery   +19 more
wiley   +1 more source

A unique combination of natural fatty acids from Hermetia illucens fly larvae fat effectively combats virulence factors and biofilms of MDR hypervirulent mucoviscus Klebsiella pneumoniae strains by increasing Lewis acid–base/van der Waals interactions in bacterial wall membranes

Frontiers in Cellular and Infection Microbiology
IntroductionHypervirulent Klebsiella pneumoniae (hvKp) and carbapenem-resistant K. pneumoniae (CR-Kp) are rapidly emerging as opportunistic pathogens that have a global impact leading to a significant increase in mortality rates among clinical patients ...
Heakal Mohamed, Heakal Mohamed, Elena Marusich, Mikhail Divashuk, Sergey Leonov, Sergey Leonov   +5 more
doaj   +1 more source

Chemotherapy and Chemoradiotherapy Studies in Oesophageal Cancer [PDF]

, 2008
The aim of this thesis was, first, to explore the use of preoperative chemoradiotherapy and palliative chemotherapy in the treatment of oesophageal cancer.
Meerten, E. (Esther) van
core   +1 more source

One‐Year Changes in Frailty Components After Curative Minimally Invasive Surgery for Colorectal Cancer in Older Patients

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Frailty predicts outcomes after colorectal cancer surgery, but postoperative changes remain unclear. We previously reported improvement in FRAIL Scale‐based frail/pre‐frail status 1 year after curative minimally invasive surgery (MIS).
Hajime Ushigome, Takuya Suzuki, Shunsuke Hayakawa, Akira Kato, Yushi Yamakawa, Kenta Saito, Hiroyuki Sagawa, Ryo Ogawa, Hiroki Takahashi, Shuji Takiguchi   +9 more
wiley   +1 more source

Long term chemoradiotherapy-related dental and skeletal complications in a young female with nasopharyngeal carcinoma

, 2010
Ioulia Ioannidou-Marathiotou1, Kyriaki Pistevou-Gompaki2, Nikolaos Eleftheriadis3, Christos Papaloukas41Department of Orthodontics, School of Dentistry, Aristotle University of Thessaloniki, 2Department of Radiation Oncology, AHEPA University Hospital ...
Ioulia Ioannidou-Marathiotou, Kyriaki Pistevou-Gompaki, Nikolaos Eleftheriadis, et al   +3 more
core