Results 51 to 60 of about 93,945 (299)

Chemotherapy and Chemoradiotherapy Studies in Oesophageal Cancer [PDF]

, 2008
The aim of this thesis was, first, to explore the use of preoperative chemoradiotherapy and palliative chemotherapy in the treatment of oesophageal cancer.
Meerten, E. (Esther) van
core   +1 more source

Temozolomide Chemoradiotherapy and Pneumocystis Pneumonia Prophylaxis [PDF]

, 2022
Background: Pneumocystis pneumonia (PCP) can occur in glioma patients receiving chemoradiotherapy. Health Canada recommends PCP prophylaxis during temozolomide chemoradiotherapy. Not all neuro-oncologists follow these recommendations.
Climans, Seth Andrew
core   +1 more source

SOX2 promotes radiotherapy resistance in lung cancer via HSP70-mediated autophagy

European Journal of Medical Research
Lung cancer is a highly prevalent malignant tumor, and radiotherapy serves as one of its primary treatment modalities. However, radiotherapy resistance significantly limits therapeutic efficacy.
Jingtao Tong, Yajie Shi, Guodong Xu, Yanggang Dan, Bingchuan Hu, Hui Zhang, Quan Xu, Kaitai Liu   +7 more
doaj   +1 more source

Adverse effects of chemoradiotherapy on invasion and metastasis of tumor cells

Genes and Diseases, 2020
The phenomenon of enhanced invasion and metastasis of residual tumor cells has been observed in an increasing number of patients receiving chemoradiotherapy recently, and tumor metastasis will undoubtedly limit patient prognosis.
Wei Xiong, Yong Liao, Ji-Yong Qin, Wen-Hui Li, Zhao-You Tang   +4 more
doaj   +1 more source

Chemoradiotherapy for locally advanced pancreatic cancer patients: is it still an open question?

, 2016
Operable pancreatic cancer is characterized by a high risk of recurrence. Efforts are made to incorporate new therapies. Throughout the world there is a lack of uniform recommendations concerning the adjuvant treatment of pancreatic cancer patients, due
Anna Mirończuk, Ewa Sierko, Emilia Sawicka, Marek Z. Wojtukiewicz   +3 more
core   +1 more source

Carcinoembryonic Antigen Messenger RNA in Pelvic Lavage Fluid Predicts Local Recurrence After Curative‐Intent Resection of Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
Pelvic lavage carcinoembryonic antigen (CEA) mRNA was quantified in 178 patients undergoing curative‐intent resection for rectal cancer. Positive pelvic lavage CEA mRNA was significantly associated with local recurrence and provided additional prognostic information beyond circumferential resection margin (CRM) status.
Hiroyuki Asai, Yushi Yamakawa, Kazuyoshi Shiga, Shuhei Uehara, Akira Kato, Takuya Suzuki, Hajime Ushigome, Hiroki Takahashi, Yoichi Matsuo, Shuji Takiguchi   +9 more
wiley   +1 more source

Beyond dual targeting: redefining the treatment horizon for true extramedullary myeloma? – a critical appraisal

Frontiers in Oncology
The management of relapsed/refractory multiple myeloma with true extramedullary disease (EMD) remains a critical challenge. The phase 2 RedirecTT-1 study evaluated the combination of two bispecific antibodies, talquetamab (anti-GPRC5D) and teclistamab ...
Qinghua Ke, Shiqiong Zhou
doaj   +1 more source

Age‐Dependent Prognostic Significance of Preoperative Transthyretin After Curative Resection for Stage I–III Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Preoperative malnutrition and systemic inflammation are established determinants of adverse outcomes in colorectal cancer (CRC). Transthyretin (TTR), a rapid‐turnover hepatic protein, reflects both nutritional and inflammatory status; however, its clinical utility may be influenced by age‐ and sex‐related variability.
Ayane Kawata, Yuji Miyamoto, Hiro Nakamura, Takahiko Akiyama, Kota Arima, Katsuhiro Ogawa, Yukiharu Hiyoshi, Masaaki Iwatsuki   +7 more
wiley   +1 more source

Impact of Histopathological Response on Outcomes After Surgical Resection Following Carbon‐Ion Radiotherapy for Pancreatic Cancer With Arterial Involvement

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Carbon‐ion radiotherapy (CIRT) provides superior dose distribution and higher biological effectiveness than conventional X‐ray radiotherapy and has emerged as a promising component of multidisciplinary treatment for advanced pancreatic ductal adenocarcinoma (PDAC).
Kenichiro Araki, Norio Kubo, Yuhei Miyasaka, Hayato Ikota, Ryo Muranushi, Mariko Tsukagoshi, Takamichi Igarashi, Masahiko Okamoto, Tatsuya Ohno, Ken Shirabe   +9 more
wiley   +1 more source

Impact of Postoperative Infectious Complications on Long‐Term Survival After Curative Resection for Colorectal Cancer: A Multicenter Study in the Minimally Invasive Era

Annals of Gastroenterological Surgery, EarlyView.
Postoperative infectious complications (PICs) have been associated with poor long‐term outcomes after colorectal cancer surgery, but evidence in the modern minimally invasive era remains limited. In this multicenter cohort of 5377 patients undergoing curative resection, PICs were independently associated with worse overall survival and relapse‐free ...
Takehito Yamamoto, Ryosuke Mizuno, Yoshiro Itatani, Tetsuya Shiota, Masahiro Yamada, Tadayoshi Yamaura, Mami Yoshitomi, Kazutaka Obama   +7 more
wiley   +1 more source