Results 31 to 40 of about 93,945 (299)

Nucleic acid-based markers of response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

, 2022
The progress that has been made in the treatment of rectal cancer has mostly resulted from multimodality strategy approach that combines surgery, chemotherapy and radiotherapy.
Nikolić, Aleksandra, Krivokapić, Zoran
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Gene and microRNA expression predictive of tumour response in patients treated with preoperative chemoradiotherapy for rectal cancer [PDF]

, 2013
Background Preoperative chemoradiotherapy (pCRT) followed by surgery is the standard treatment for locally advanced rectal cancer (LARC). However, the response to pCRT is not uniform, and there is no effective method to predict tumour response to pCRT ...
Maretto, I
core  

Sequential Evaluation of Swallowing Function During Chemoradiotherapy for Head and Neck Cancer [PDF]

[Background] Many studies have addressed chronic dysphagia resulting from chemoradiotherapy for head and neck cancer (HNC) because of its severity, but changes in the swallowing function during chemoradiotherapy has been rarely reported. This study aimed
Fukuhara, Takahiro, Fujiwara, Kazunori, Morisaki, Tsuyoshi, 100002206, 369, Taira, Kenkichiro, Koyama, Satoshi, 16778, 16777, 405, 80403418, 100001318, 90403419, 4942, 100000417   +14 more
core   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

B cells in nasopharyngeal carcinoma: From prognostic signal to therapeutic hypothesis—A critical appraisal of the RATIONALE-309 biomarker analysis

Translational Oncology
The 3-year follow-up of the phase 3 RATIONALE-309 trial confirmed sustained progression-free and overall survival (OS) benefit with tislelizumab plus gemcitabine-cisplatin in recurrent/metastatic nasopharyngeal carcinoma (R/M NPC).
Qing-Hua Ke, Shi-Qiong Zhou
doaj   +1 more source

Chemoradiotherapy in pancreatic carcinoma

Indian Journal of Medical and Paediatric Oncology, 2009
AbstractPancreatic cancer patients present late in their course and surgical resection as a modality of treatment is of limited value. Majority develop loco-regional failure and distant metastasis, therefore, adjuvant therapy comprising of radiotherapy and chemotherapy are useful treatment options to achieve higher loco-regional control.
Pathy Sushmita, Chander Subhash
openaire   +4 more sources

The Role of NF-κB/MIR155HG in Regulating the Stemness and Radioresistance in Breast Cancer Stem Cells

Frontiers in Bioscience-Landmark
Background: Breast cancer stem cells (BCSCs) are instrumental in treatment resistance, recurrence, and metastasis. The development of breast cancer and radiation sensitivity is intimately pertinent to long non-coding RNA (lncRNA). This
Yunbao Xu, Lu Yang, Guangming Li, Chuangzhou Rao   +3 more
doaj   +1 more source

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Survival Impact of Adjuvant Chemoradiotherapy in Resected Pancreatic Cancer [PDF]

Aim: Pancreatic cancer (PC) is one of the most aggressive cancers, with a 5-year survival rate of less than 50% in resectable stages. The aim of this study was to determine the survival effect of adjuvant chemoradiotherapy (CRT) in resected PC ...
Yakup İRİAĞAÇ, Abdullah SAKİN, Eyyüp ÇAVDAR, Yüksel BEYAZ, Okan AVCI, Kubilay KARABOYUN   +5 more
core   +1 more source