Results 31 to 40 of about 87,239 (208)

Gene and microRNA expression predictive of tumour response in patients treated with preoperative chemoradiotherapy for rectal cancer [PDF]

, 2013
Background Preoperative chemoradiotherapy (pCRT) followed by surgery is the standard treatment for locally advanced rectal cancer (LARC). However, the response to pCRT is not uniform, and there is no effective method to predict tumour response to pCRT ...
Maretto, I
core  

Sequential Evaluation of Swallowing Function During Chemoradiotherapy for Head and Neck Cancer [PDF]

[Background] Many studies have addressed chronic dysphagia resulting from chemoradiotherapy for head and neck cancer (HNC) because of its severity, but changes in the swallowing function during chemoradiotherapy has been rarely reported. This study aimed
Fukuhara, Takahiro, Fujiwara, Kazunori, Morisaki, Tsuyoshi, 100002206, 369, Taira, Kenkichiro, Koyama, Satoshi, 16778, 16777, 405, 80403418, 100001318, 90403419, 4942, 100000417   +14 more
core   +1 more source

Role of neoadjuvant chemoradiotherapy in liver transplantation for unresectable perihilar cholangiocarcinoma: multicentre, retrospective cohort study [PDF]

, 2023
International audienceAbstract Background The Mayo protocol for liver transplantation in patients with unresectable perihilar cholangiocarcinoma is based on strict selection and neoadjuvant chemoradiotherapy.
Boleslawski, Emmanuel, Kuipers, H., Dubbeld, Jeroen, Ijzermans, Jan N.M., Dubbeld, J., Polak, Wojciech, Alwayn, I.P.J., Muscari, F., Mabrut, J.Y., van Hoek, Bart, Hoogwater, F.J.H., van Vilsteren, Frederike, Kuipers, Hendrien; id_orcid, Alwayn, Ian P.J., Ijzermans, J.N.M., De Meijer, Vincent E.; id_orcid, de Meijer, Vincent, Porte, Robert, Polak, W.G., Rayar, Michel, Boleslawski, E., Muscari, Fabrice, Chebaro, Alexandre, Kuipers, Hendrien, Meijer, V.E. de, Porte, R.J., Rayar, M., Jezequel, C., De Meijer, Vincent E., Mabrut, Jean‐yves, Adam, J.P., Hoek, B. van, Mohkam, Kayvan, Van Vilsteren, Frederike G.I., Chebaro, A., Murad, Sarwa Darwish, Adam, Jean-Philippe, Alwayn, Ian, Vilsteren, F.G.I. van, Hoogwater, Frederik J.H., Hoogwater, Frederik, Maulat, C., Polak, Wojciech G.; id_orcid, Chiche, Laurence, Murad, S.D., Ijzermans, Jan, Mabrut, Jean Yves, Polak, Wojciech G., Chiche, L., Mohkam, K., Jézéquel, Caroline, Adam, Jean Philippe, Porte, Robert J., Maulat, Charlotte   +53 more
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Exploring the Role of Ubiquitin-Proteasome System in the Pathogenesis of Parkinson’s Disease

Pharmaceuticals
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder among the elderly population. The pathogenesis of PD encompasses genetic alterations, environmental factors, and age-related neurodegenerative processes.
Yiting Zhao, Man Lin, Fengguang Zhai, Jun Chen, Xiaofeng Jin   +4 more
doaj   +1 more source

Neoadjuvant sequential chemoradiotherapy versus radiotherapy alone for treatment of high-risk extremity soft tissue sarcoma: a single-institution experience [PDF]

, 2017
Aim of the study : Patients with large and high-grade extremity soft-tissue sarcoma are at significant risk for distant metastasis and sarcoma-related death.
Agaoglu, Fulya, Meltem Ekenel, Karabulut, Senem, Emin Darendeliler, Fulya Ağaoğlu, Darendeliler, Emin, Leyla Kılıç, Senem Karabulut, Ekenel, MELTEM, Kilic, Leyla   +9 more
core   +1 more source

The Role of NF-κB/MIR155HG in Regulating the Stemness and Radioresistance in Breast Cancer Stem Cells

Frontiers in Bioscience-Landmark
Background: Breast cancer stem cells (BCSCs) are instrumental in treatment resistance, recurrence, and metastasis. The development of breast cancer and radiation sensitivity is intimately pertinent to long non-coding RNA (lncRNA). This
Yunbao Xu, Lu Yang, Guangming Li, Chuangzhou Rao   +3 more
doaj   +1 more source

Survival Impact of Adjuvant Chemoradiotherapy in Resected Pancreatic Cancer [PDF]

Aim: Pancreatic cancer (PC) is one of the most aggressive cancers, with a 5-year survival rate of less than 50% in resectable stages. The aim of this study was to determine the survival effect of adjuvant chemoradiotherapy (CRT) in resected PC ...
Yakup İRİAĞAÇ, Abdullah SAKİN, Eyyüp ÇAVDAR, Yüksel BEYAZ, Okan AVCI, Kubilay KARABOYUN   +5 more
core   +1 more source

Adverse effects of chemoradiotherapy on invasion and metastasis of tumor cells

Genes and Diseases, 2020
The phenomenon of enhanced invasion and metastasis of residual tumor cells has been observed in an increasing number of patients receiving chemoradiotherapy recently, and tumor metastasis will undoubtedly limit patient prognosis.
Wei Xiong, Yong Liao, Ji-Yong Qin, Wen-Hui Li, Zhao-You Tang   +4 more
doaj   +1 more source

Chemoradiotherapy for locally advanced pancreatic cancer patients: is it still an open question?

, 2016
Operable pancreatic cancer is characterized by a high risk of recurrence. Efforts are made to incorporate new therapies. Throughout the world there is a lack of uniform recommendations concerning the adjuvant treatment of pancreatic cancer patients, due
Anna Mirończuk, Ewa Sierko, Emilia Sawicka, Marek Z. Wojtukiewicz   +3 more
core   +1 more source

SOX2 promotes radiotherapy resistance in lung cancer via HSP70-mediated autophagy

European Journal of Medical Research
Lung cancer is a highly prevalent malignant tumor, and radiotherapy serves as one of its primary treatment modalities. However, radiotherapy resistance significantly limits therapeutic efficacy.
Jingtao Tong, Yajie Shi, Guodong Xu, Yanggang Dan, Bingchuan Hu, Hui Zhang, Quan Xu, Kaitai Liu   +7 more
doaj   +1 more source