Comparative outcomes of neoadjuvant immunochemotherapy versus neoadjuvant chemoradiotherapy in locally advanced thoracic esophageal squamous cell carcinoma: a target trial emulation. [PDF]
Li Z +9 more
europepmc +1 more source
ABSTRACT Background Prophylactic cranial irradiation (PCI) has traditionally been a cornerstone of treatment in limited‐stage and extensive‐stage small cell lung cancer (SCLC). Recent evidence suggests that active MRI brain surveillance may result in comparable overall survival (OS) and progression‐free survival (PFS).
Zhao Feng Liu +7 more
wiley +1 more source
Real-World Outcomes of Weekly Paclitaxel-Carboplatin-Based Chemoradiotherapy Versus Cisplatin-Based Chemoradiotherapy for FIGO Stage IB2-IVA Cervical cancer: A Retrospective Observational Study. [PDF]
Shimizu A +5 more
europepmc +1 more source
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski +7 more
wiley +1 more source
Stress, breast cancer, and the epigenetic echo: moving beyond the polygenic narrative?
Shiqiong Zhou, Qinghua Ke
doaj +1 more source
Prospective Assessment of Short-Term Response and Acute Toxicity With Accelerated Fractionation Radiotherapy Versus Concurrent Chemoradiotherapy in Locally Advanced Cervical Cancer. [PDF]
Das P +4 more
europepmc +1 more source
Expanding on the growing evidence for neoadjuvant immunotherapy in resectable non‐small cell lung cancer, this study explored neoadjuvant nivolumab ± denosumab. Two of the 10 treated patients achieved a pathological complete response. CD8 T‐cell infiltration correlated with pathological response, warranting ongoing translational research to understand ...
Elizabeth Ahern +11 more
wiley +1 more source
Survival and Pathologic Response After Neoadjuvant Treatment in Esophagogastric Cancer: A Systematic Review. [PDF]
Marica RE +11 more
europepmc +1 more source
Lung V5 and the planning target volume/lung volume ratio were identified as independent dosimetric risk factors for clinically significant radiation pneumonitis following moderately hypofractionated radiotherapy for lung cancer. Maintaining V5 < 35% may help mitigate this risk in clinical practice.
YuanYou Yang +3 more
wiley +1 more source

