Results 201 to 210 of about 97,795 (300)

A Word of Caution: Watch and Wait in the Total Mesorectal Excision Era

open access: yesANZ Journal of Surgery, EarlyView.
Among 573 patients undergoing long‐course neoadjuvant chemoradiotherapy and total mesorectal excision between 2006 and 2020, five‐year overall survival was 85.7%. Local recurrence was 3.4% and metastatic recurrence was 16.5%. Pathological stage and tumour regression grade stratified long‐term outcomes, providing regional benchmarks for evaluating organ‐
K. Broughton   +11 more
wiley   +1 more source

Long‐term quality of life in patients with bladder cancer following radical cystectomy

open access: yesBJU International, Volume 135, Issue 4, Page 675-683, April 2025.
Objectives To investigate changes in quality of life (QoL) up to 8 years after radical cystectomy (RC) and compare QoL after RC with a gender‐ and age‐matched Dutch normative population. Furthermore, we aimed to identify patient characteristics associated with QoL and QoL trajectories after RC.
Emine Akdemir   +8 more
wiley   +1 more source

Efficacy and Safety of DVDMS‐Photodynamic Therapy for Dysphagia in Advanced Esophageal Cancer: A Phase II Clinical Trial

open access: yesCancer Science, EarlyView.
In this single‐arm Phase II trial, cosiporfin sodium‐mediated photodynamic therapy demonstrated efficacy in alleviating dysphagia and improving quality of life for patients with advanced esophageal cancer, with rapid onset, sustained efficacy, and good tolerability.
Jun Zhou   +14 more
wiley   +1 more source

Integrative machine learning for identifying transcriptomic signatures of neoadjuvant chemoradiotherapy response in locally advanced rectal cancer. [PDF]

open access: yesBiochem Biophys Rep
Mirghayed MMR   +8 more
europepmc   +1 more source

Myofibroblast‐Like CAFs in Metastatic Lymph Nodes Drive Tumor Stemness and Poor Prognosis in Head and Neck Cancer

open access: yesCancer Science, EarlyView.
Compared with PT‐CAFs, LN‐CAFs exhibited a myofibroblast‐like phenotype, enhanced tumor stemness‐promoting activity, and fibrosis‐, EMT‐, and hypoxia‐related transcriptomic signatures. LN‐CAF‐related gene signatures were independently associated with poor prognosis in head and neck squamous cell carcinoma.
Hiroyuki Hagiwara   +8 more
wiley   +1 more source

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