Results 201 to 210 of about 93,945 (299)

Prospective multicentre study evaluating ctDNA as a biomarker of residual disease after chemoradiotherapy for locally advanced head and neck squamous cell carcinoma: NeckTAR-IN protocol. [PDF]

BMJ Open
Ginzac A, Ventelou L, Ferreira MC, Canetti L, Biau J, Molnar I, Ponelle-Chachuat F, Philippe S, Saroul N, Pham-Dang N, Durando X, Bernadach M.   +11 more
europepmc   +1 more source

Long‐term quality of life in patients with bladder cancer following radical cystectomy

BJU International, Volume 135, Issue 4, Page 675-683, April 2025.
Objectives To investigate changes in quality of life (QoL) up to 8 years after radical cystectomy (RC) and compare QoL after RC with a gender‐ and age‐matched Dutch normative population. Furthermore, we aimed to identify patient characteristics associated with QoL and QoL trajectories after RC.
Emine Akdemir, Martijn M. Stuiver, Maaike W. van de Kamp, Jolanda Bloos ‐ van der Hulst, Laura S. Mertens, Kees Hendricksen, Wim H. van Harten, Anne M. May, Maike G. Sweegers   +8 more
wiley   +1 more source

Higher pre-treatment lymphocyte-to-monocyte ratio predicts better tumor shrinkage after external beam radiotherapy in locally advanced cervical cancer. [PDF]

Front Oncol
Qiu L, Li Y, Wang Y, Xie Y, Zhuo Y.
europepmc   +1 more source

Feiwei Heji Enhances Antitumor Immunity by MLL4‐Dependent Regulation of Pyroptosis in Lung Cancer

Cancer Science, EarlyView.
Feiwei Heji suppresses lung tumor growth by downregulating MLL4 and activating caspase‐1/GSDMD‐associated pyroptosis. This pyroptosis‐related inflammatory response enhances CD8+ T‐cell‐mediated antitumor immunity, revealing an MLL4‐pyroptosis‐immune axis underlying the therapeutic activity of Feiwei Heji.
Nan Cheng, Ruoyu Jiang, Wei Li, Wenjie Huang, Qiao Peng, Tong Zhao, Chufeng Zhang   +6 more
wiley   +1 more source

ATF4, ZIK1, and PNMA3 Transcriptomic Signatures Predict Chemoradiotherapy Response in Cervical Cancer. [PDF]

Cancer Med
de Melo Neto AB, Queiroz FR, de Souza Melo CP, Duarte BCD, Ferreira JGG, de Amorim IFG, do Amaral LR, Bertarini PLL, de Figueiredo Franco TMR, de Carvalho AT, Martins-Filho OA, de Jesus Jeremias W, da Conceição Braga L, de Oliveira Salles PG, de Souza Gomes M.   +14 more
europepmc   +1 more source

Repression of ROBO1 Enhances Cisplatin Sensitivity in Hypermethylated Subtype of HPV‐Positive Head and Neck Carcinoma

Cancer Science, EarlyView.
DNA hypermethylation causally correlates with better treatment response of HPV(+) HNSCC, and its chemosensitivity might be enhanced by silencing of methylation target genes. Silencing of ROBO1 enhances, and its overexpression reduces, CDDP chemosensitivity, and epigenetic or ROBO1‐targeted interventions may improve therapeutic outcomes in resistant HPV(
Kenta Saeda, Takuya Nakagawa, Atsushi Okabe, Kazuko Kita, Tomoya Kurokawa, Masaki Fukuyo, Hiroki Ueda, Motoaki Seki, Bahityar Rahmutulla, Syuji Yonekura, Toyoyuki Hanazawa, Atsushi Kaneda   +11 more
wiley   +1 more source

Establishment of a chemoradio-resistance colorectal cancer cell model and its changes in biological behavior. [PDF]

J Gastrointest Oncol
Liu S, Zhang Z, An Q, Jia Y, Su Q, Zhu D, Luan L, Yang H, Chuan Z, Liu X, Wang S, Liu Y, Fu F, Sun Q, Ma L, Yang J, Zhang Y, Duan M, Yao P, Yang C, Xing Y, Shen H, Jiang Y.   +22 more
europepmc   +1 more source

Decreased Expression by a Chemically Modified siRNA to PTBP1 Seriously Affects Warburg Effect in Colorectal Cancer Cells

Cancer Science, EarlyView.
Chemically modified siR‐PTBP1 disrupts the Warburg effect by reprogramming pyruvate kinase splicing from PKM2 to PKM1. This metabolic shift activates the TCA cycle, increases ATP production, and excessive ROS generation, and ultimately induces apoptotic cell death in colorectal cancer cells.
Keita Matsumoto, Hirokatsu Hayashi, Yoshihisa Tokumaru, Seito Fujibayashi, Noriki Mitsui, Masahide Endo, Takeshi Horaguchi, Yuji Hatanaka, Ryoma Yokoi, Chika Mizutani, Masashi Kuno, Masahiro Fukada, Ryuichi Asai, Itaru Yasufuku, Yuta Sato, Jesse Yu Tajima, Yoshihiro Tanaka, Remi Nakashima, Yukihiro Akao, Nobuhisa Matsuhashi   +19 more
wiley   +1 more source

Four-Year Survival Outcomes of Personalized Total Neoadjuvant Therapy Versus Chemotherapy During the 'Wait Period' Versus Standard Chemoradiotherapy for Locally Advanced Rectal Cancer. [PDF]

J Gastrointest Cancer
Bedrikovetski S, Bunjo Z, Murshed I, Moore JW, Sammour T.   +4 more
europepmc   +1 more source

Efficacy and Safety of DVDMS‐Photodynamic Therapy for Dysphagia in Advanced Esophageal Cancer: A Phase II Clinical Trial

Cancer Science, EarlyView.
In this single‐arm Phase II trial, cosiporfin sodium‐mediated photodynamic therapy demonstrated efficacy in alleviating dysphagia and improving quality of life for patients with advanced esophageal cancer, with rapid onset, sustained efficacy, and good tolerability.
Jun Zhou, Shegan Gao, Jiajia Yuan, Hao Chen, Yongqian Shu, Huizhen Fan, Yanshuo Cao, Tanyou Shan, Caihong Dong, Hao Zhang, Qingting Song, Baobao Xin, Hao Zhang, Zhihao Lu, Lin Shen   +14 more
wiley   +1 more source