Results 211 to 220 of about 93,945 (299)

Myofibroblast‐Like CAFs in Metastatic Lymph Nodes Drive Tumor Stemness and Poor Prognosis in Head and Neck Cancer

open access: yesCancer Science, EarlyView.
Compared with PT‐CAFs, LN‐CAFs exhibited a myofibroblast‐like phenotype, enhanced tumor stemness‐promoting activity, and fibrosis‐, EMT‐, and hypoxia‐related transcriptomic signatures. LN‐CAF‐related gene signatures were independently associated with poor prognosis in head and neck squamous cell carcinoma.
Hiroyuki Hagiwara   +8 more
wiley   +1 more source

Local excision for anal squamous cell carcinoma: challenges in patient selection and diagnosis. [PDF]

open access: yesArq Bras Cir Dig
Sobrado LF   +7 more
europepmc   +1 more source

Research Progress and Future Directions in Immune Cell Crosstalk in the Esophageal Cancer: A Bibliometric Analysis. [PDF]

open access: yesJ Inflamm Res
Zhang C   +10 more
europepmc   +1 more source

Surgical Complexity and Perioperative Feasibility Following Neoadjuvant Chemotherapy, Chemoradiotherapy, or Chemoimmunotherapy in Stage II-III Non-Small Cell Lung Cancer: A Retrospective Single-Institution Study. [PDF]

open access: yesCancers (Basel)
Sakai H   +12 more
europepmc   +1 more source

Laryngeal Cancer Survival in Northern United Kingdom: A Multi‐Centre Retrospective Observational Study

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Objectives Laryngeal cancer incidence has risen globally, yet survival outcomes have shown limited improvement over recent decades. This study evaluated contemporary outcomes across multiple centres in Northern UK and examined stage‐ and treatment‐specific survival. Design Multi‐centre retrospective observational study.
Amar Rajgor   +54 more
wiley   +1 more source

Dental Pulp Stem Cell‐Derived Intracellular Vesicles Inhibit OSCC by Delivering PTEN to Suppress PI3K/AKT/mTOR Signalling Pathway

open access: yesCell Proliferation, EarlyView.
DPSC‐IVs suppressed PI3K/AKT/mTOR signalling pathway by delivering PTEN to tumour cells, which reduced the expression of Bcl‐2 and elevated that of Bax. Meanwhile, DPSC‐IVs activated PINK1/Parkin mediated mitophagy, which further raised ROS levels.
Yu Luo   +10 more
wiley   +1 more source

Single‐Cell and Spatial Analysis Reveal the Differences Between Left‐Sided and Right‐Sided Colorectal Cancer

open access: yesCell Proliferation, EarlyView.
Single‐cell and spatial analysis revealed distinct CRC microenvironments by tumour laterality. Right‐sided tumours showed enhanced germinal centre B cells, CXCL13+ T cells, and organized TLS‐immune crosstalk via CCL19/21‐CCR7, suggesting better immunotherapy response.
Zongnai Zhang   +8 more
wiley   +1 more source

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