Results 81 to 90 of about 133,417 (336)

Beyond Concurrent Chemoradiation: The Emerging Role of PD-1/PD-L1 Inhibitors in Stage III Lung Cancer. [PDF]

, 2018
Concurrent chemoradiation (cCRT) with platinum-based chemotherapy is standard-of-care therapy for patients with stage III unresectable non-small cell lung cancer (NSCLC).
Dicker, Adam P., Lu, Bo, McCall, Neal S.
core   +1 more source

Bronchial and arterial sleeve resection for centrally-located lung cancers [PDF]

, 2016
The use of bronchial and arterial sleeve resections for the treatment of centrally-located lung cancers, when available, has become the option of choice in comparison with pneumonectomy (PN). Technical expertise, in particular in vascular reconstruction,
D'Andrilli, Antonio, Maurizi, Giulio, Rendina, Erino Angelo, Venuta, Federico   +3 more
core   +1 more source

Artificial Intelligence‐Guided Total Mesorectal Excision: Development of a Deep Learning Model to Identify the Pelvic Fascial Plane Anatomy

Annals of Gastroenterological Surgery, EarlyView.
AI‐based segmentation of fascial planes during total mesorectal excision. Ground truth and predicted boundaries are compared for mesorectal fascia (blue), parietal pelvic fascia (red), and the holy plane (white). ABSTRACT Aim Total mesorectal excision entails dissection of the “holy plane” without damaging the mesorectal and parietal pelvic fasciae. We
Yuta Suzuki, Daichi Kitaguchi, Norihito Kosugi, Hiro Hasegawa, Nobuyoshi Takeshita, Yusuke Kinugasa, Masaaki Ito   +6 more
wiley   +1 more source

High survivin expression as a risk factor in patients with anal carcinoma treated with concurrent chemoradiotherapy [PDF]

, 2012
Purpose: To investigate the prognostic value of survivin expression in pretreatment specimens from patients with anal cancer treated with concurrent 5-FU and mitomycin C-based chemoradiation (CRT).
Distel, Luitpold Valentin Rudolf, Falk, Stefan, Fraunholz, Ingeborg, Kohler, Daniela, Rave-Fränk, Margret, Rödel, Claus, Rödel, Franz   +6 more
core   +2 more sources

Impact of Tumor Location on the Efficacy of Lateral and Mesenteric Lymph Node Dissection in Patients With Rectal Cancer Treated by Upfront Surgery

Annals of Gastroenterological Surgery, EarlyView.
This study examined the impact of tumor location on lymph node metastasis (LNM) patterns and the efficacy of lymph node dissection in rectal cancer. Analyzing 882 patients who underwent total mesorectal excision with lateral lymph node dissection, we found that mesenteric LNM rates were higher in tumors located more orally, whereas lateral LNM rates ...
Tomofumi Uotani, Hiroshi Nagata, Yasuyuki Takamizawa, Konosuke Moritani, Shunsuke Tsukamoto, Tsutomu Fujii, Yukihide Kanemitsu   +6 more
wiley   +1 more source

Suppression of the postoperative neutrophil leucocytosis following neoadjuvant chemoradiotherapy for rectal cancer and implications for surgical morbidity [PDF]

, 2010
Objective: The extent to which neoadjuvant chemoradio- therapy for rectal cancer influences postoperative morbid- ity is controversial. This study investigated whether this treatment suppresses the normal perioperative inflamma- tory response and ...
Anonymous, Artioukh, Bosset, Buie, Bujko, Bullard, Cohen, Gerard, Goldberg, Hartley, Kerr, Marijnen, Pahlman, Royal College of Pathologists Working Group on Cancer Services, Sauer, Wichmann, Wong   +16 more
core   +1 more source

Clinical outcomes of chemoradiotherapy for locally recurrent rectal cancer

Radiation Oncology, 2011
Background To assess the clinical outcome of chemoradiotherapy with or without surgery for locally recurrent rectal cancer (LRRC) and to find useful and significant prognostic factors for a clinical situation.
Oh Jae Hwan, Choi Hyo Seong, Park Ji Won, Kim Sun Young, Kim Dae Yong, Lee Joo Ho, Chang Hee Jin, Kim Tae Hyun, Park Suk Won   +8 more
doaj   +1 more source

Safety and Efficacy of Pelvic Reinforcement Procedure for Preventing Postoperative Perineal Hernia After Robotic Abdominoperineal Resection: A Single‐Center, Retrospective Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to investigate the safety and efficacy of pelvic reinforcement procedure (PRP) in robotic abdominoperineal resection (Ro‐APR). PRP‐ had a significantly higher rate of imaged perineal hernia (PH) (39.2% vs. 6.7%, p = 0.005) and symptomatic PH (19.6% vs.
Yoshihiro Sakai, Shunsuke Kasai, Akio Shiomi, Shoichi Manabe, Yusuke Yamaoka, Yusuke Tanaka, Takahiro Igaki, Hiroyasu Kagawa, Yusuke Kinugasa   +8 more
wiley   +1 more source

Mechanism of Lenvatinib Resistance via Exosomal miRNA‐132/Nrf2 Axis in Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
Exosomal miRNA‐132 from LVT‐res HCC cells activated Nrf2 expression through the PTEN/GSK3β pathway in recipient cells. This cascade could induce drug resistance in non‐resistant HCC cells in the TME. ABSTRACT Introduction Lenvatinib is a multiple receptor tyrosine kinase inhibitor and a first‐line targeted therapy for hepatocellular carcinoma (HCC ...
Chie Takasu, Chiharu Nakasu, Yu Saito, Yuji Morine, Tetsuya Ikemoto, Shinichiro Yamada, Hiroki Teraoku, Mitsuo Shimada   +7 more
wiley   +1 more source

Clinical benefit of adding oxaliplatin to standard neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a meta-analysis : Oxaliplatin in neoadjuvant treatment for rectal cancer [PDF]

, 2017
. Background: To evaluate the treatment tolerance and clinical outcomes in patients aged 70 years and older with locally advanced oropharyngeal cancer treated by definitive intensity-modulated radiation therapy (IMRT).
Benevento, Ilaria, Bulzonetti, Nadia, Caiazzo, Rossella, DE FELICE, Francesca, Magnante, ANNA LISA, Musio, Daniela, Tombolini, Vincenzo   +6 more
core   +1 more source