A chemostat-based model for growing bacterial biofilms [PDF]
Microbiology SpectrumBiofilms are groups of microbes that live together in dense communities, often attached to a surface. They play an outsized role in all aspects of microbial life, from chronic infections to biofouling to dental decay.
Fabrizio Spagnolo +11 more
doaj +6 more sources
Complexity, 2019 In this paper, we formulate and investigate a two-microorganism and single nutrient chemostat model with Monod-Haldane response function and random perturbation.
Mengnan Chi, Wencai Zhao
doaj +3 more sources
Activities of Cefiderocol with Simulated Human Plasma Concentrations against Carbapenem-Resistant Gram-Negative Bacilli in an In Vitro Chemostat Model. [PDF]
Antimicrob Agents Chemother, 2020 Activities of cefiderocol under simulated human plasma concentrations at the recommended dosing regimen of 2 g every 8 h with a 3-h infusion were evaluated using an in vitro chemostat model.
Matsumoto S +3 more
europepmc +2 more sources
Overriding Bioprocess Perturbations With a Cell-Machine Interface for Reliable Microbial Stress-Response Control. [PDF]
Microb BiotechnolThe environmental perturbations imposed by the cell–machine interface dominate over mixing‐induced heterogeneities and drive cell population homogeneity. ABSTRACT Controlling cell population dynamics and phenotypic diversification is a key objective in systems and synthetic biology, particularly for ensuring uniform responses from engineered gene ...
Delvenne M +6 more
europepmc +2 more sources
Mathematical Modelling and Intuition in Microbiology: A Perspective. [PDF]
Environ MicrobiolMathematical modelling in microbiology converts verbal reasoning into internally consistent hypotheses that can provide testable predictions, infer hidden parameters, and generate transferable intuition. By selecting an appropriate level of description, researchers can connect data to explanatory principles.
Lopez JA, Erez A.
europepmc +2 more sources
The existence of stationary distribution of a stochastic delayed chemostat model
Applied Mathematics Letters, 2019 In this paper, based on the existing literature, we further study an important statistical character of a stochastic delayed chemostat model. By constructing suitable Lyapunov functional and using the stochastic Lyapunov analysis method, we investigate ...
Xiaofeng Zhang, R. Yuan
exaly +2 more sources
Stationary distribution of a stochastic food chain chemostat model with general response functions
Applied Mathematics Letters, 2019 In this paper, we focus on a food chain chemostat model with general response functions, perturbed by white noise. Under appropriate assumptions, we establish sufficient conditions for the existence of a unique ergodic stationary distribution by using ...
Miaomiao Gao, Daqing Jiang, Li Zu
exaly +2 more sources
Coexistence in a two species chemostat model with Markov switchings
Applied Mathematics Letters, 2019 This paper formulates a new switched two species chemostat model and discusses the coexistence behavior in the chemostat. A complete classification on the single-species chemostat is carried out firstly, where the stationary distribution with ergodicity ...
Haidong Liu
exaly +2 more sources
Transferability of bioprocessing modes for recombinant protease production: from fed-batch to continuous cultivation with Bacillus licheniformis [PDF]
BMC BiotechnologyBackground Proteases are essential in various industries due to their unique substrate specificities and robustness in different operational conditions.
Stefan Kittler +7 more
doaj +2 more sources
Analysis of early childhood intestinal microbial dynamics in a continuous-flow bioreactor [PDF]
MicrobiomeBackground The human gut microbiota is inoculated at birth and undergoes a process of assembly and diversification during the first few years of life. Studies in mice and humans have revealed associations between the early-life gut microbiome and future ...
Alessandra Granato +8 more
doaj +2 more sources