Overriding Bioprocess Perturbations With a Cell-Machine Interface for Reliable Microbial Stress-Response Control. [PDF]
Microb BiotechnolThe environmental perturbations imposed by the cell–machine interface dominate over mixing‐induced heterogeneities and drive cell population homogeneity. ABSTRACT Controlling cell population dynamics and phenotypic diversification is a key objective in systems and synthetic biology, particularly for ensuring uniform responses from engineered gene ...
Delvenne M +6 more
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Stable coexistence and phenol-degradation expression of Cupriavidus sp. strain P-10 and Comamonas thiooxydans strain R2 in phenol-competitive chemostat culture [PDF]
Applied Microbiology and BiotechnologyWe investigated the mechanism underlying the coexistence of the phenol-degrading bacteria Cupriavidus sp. strain P-10 and Comamonas thiooxydans strain R2 using a chemostat culture supplemented with phenol as the sole carbon and energy source ...
Kenshi Suzuki +6 more
doaj +2 more sources
Mathematical Modelling and Intuition in Microbiology: A Perspective. [PDF]
Environ MicrobiolMathematical modelling in microbiology converts verbal reasoning into internally consistent hypotheses that can provide testable predictions, infer hidden parameters, and generate transferable intuition. By selecting an appropriate level of description, researchers can connect data to explanatory principles.
Lopez JA, Erez A.
europepmc +2 more sources
Riboflavin Production by Steady-State Continuous Cultures of Hyphopichia wangnamkhiaoensis in a Bubble Column Bioreactor [PDF]
MicroorganismsRiboflavin is biosynthesized and excreted extracellularly by the novel yeast Hyphopichia wangnamkhiaoensis. The steady-state kinetics of cell growth, substrate consumption, and riboflavin production by H.
Raziel Arturo Jiménez-Nava +2 more
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Chances and drawbacks of derepressed recombinant enzyme production in continuous cultivations with Komagataella phaffii [PDF]
Frontiers in Bioengineering and BiotechnologyUtilizing Komagataella phaffii (K. phaffii) as a host, methanol-dependent fed-batch cultivations remain state-of-the-art for recombinant protein production.
Mihail Besleaga +4 more
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HOPF bifurcation of the chemostat with delay and simplified holling type-iv response function [PDF]
MATEC Web of Conferences, 2020 In this paper, the author investigates Chemostat with Delay and Simplifified Holling Type-IV Response Function, which more match the actual meaning in the chemostat system. Using bifurcation theory, we discuss the hopf bifurcation stability in detail.
Li Yanqiu
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Animals, 2022 The equine gastrointestinal (GI) microbiota is intimately related to the horse. The objective of the current study was to evaluate the microbiome and metabolome of cecal inoculum maintained in an anaerobic chamber or chemostat batch fermenter, as well as
Jennifer L. MacNicol +5 more
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Dynamical bifurcation of a sewage treatment model with general higher-order perturbation
Results in Physics, 2022 In this research, we expose new results on the dynamics of a high disturbed chemostat model for industrial wastewater. Due to the complexity of heavy and erratic environmental variations, we take into consideration the polynomial perturbation.
Yassine Sabbar +6 more
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Dynamical behaviors of stochastic chemostat model with general response functions
上海师范大学学报. 自然科学版, 2022 In this paper, a stochastic chemostat model with general response functions is studied. Meanwhile, it first proves the existence and uniqueness of the globally positive solutions for the model.
GUO Yi, JI Yue, DING Yu, LYU Xiang
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Single-Cell Technologies to Understand the Mechanisms of Cellular Adaptation in Chemostats
Frontiers in Bioengineering and Biotechnology, 2020 There is a growing interest in continuous manufacturing within the bioprocessing community. In this context, the chemostat process is an important unit operation.
Naia Risager Wright +3 more
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