Results 1 to 10 of about 44,737 (248)
Prochiral pyrmetazole can be asymmetrically oxidized into (S)-omeprazole, a proton pump inhibitor that is used to treat gastroesophageal reflux, by an engineered cyclohexanone monooxygenase (CHMO Acineto -Mut) that has high stereoselectivity.
Ya-Jing Li +6 more
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Highlight Efficiency of bioreduction of sulfate and biomass can be increased by CdS NPs. It is important for the EPS of RSB to improve the sulfate reduction efficiency. Utilization efficiency of extracellular electrons by RSB can be enhanced through EPS.
Guoqing Cheng +6 more
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De novo synthesis of nervonic acid and optimization of metabolic regulation by Yarrowia lipolytica
Nervonic acid, a natural fatty acid compound and also a core component of nerve fibers and nerve cells, has been widely used to prevent and treat related diseases of the brain nervous system.
Xin-Ru Zhao +6 more
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Expression of recombinant human Apolipoprotein A-IMilano in Nicotiana tabacum
Apolipoprotein A-IMilano (Apo A-IMilano) is a natural mutant of Apolipoprotein. It is currently the only protein that can clear arterial wall thrombus deposits and promptly alleviate acute myocardial ischemia.
Wei Zhao +9 more
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Ferroptosis is closely linked to various cancers, including lung adenocarcinoma (LUAD); however, the factors involved in the regulation of ferroptosis-related genes are not well established.
Yugang Guo +8 more
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Ansamitocin P-3 (AP-3) produced by Actinosynnema pretiosum is a potent antitumor agent. However, lack of efficient genome editing tools greatly hinders the AP-3 overproduction in A. pretiosum.
Siyu Guo +6 more
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During the ex vivo expansion of umbilical cord-derived mesenchymal stem cells (hUCMSCs) in a stirred tank bioreactor, the formation of cell–microcarrier aggregates significantly affects cell proliferation and physiological activity, making it difficult ...
Botao Zhang +6 more
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Background Compared with shake flask, bioreactor offers a relatively stable and controllable extracellular environment for cell growth and metabolism.
Xiwei Tian +8 more
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Vitamin combination promotes ex vivo expansion of NK-92 cells by reprogramming glucose metabolism
Robust ex vivo expansion of NK-92 cells is essential for clinical immunotherapy. The vitamin B group is critical for the expansion and function of immune cells.
Yan Fu +5 more
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Background Adipose-derived mesenchymal stem cells (ADMSCs) are considered an efficient and important candidate for male infertility treatment because they contain pluripotent stem cells, which can differentiate into all cells from three germ layers ...
Yanxia Luo +9 more
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