Results 21 to 30 of about 44,737 (248)

Transposon insertion sequencing reveals T4SS as the major genetic trait for conjugation transfer of multi-drug resistance pEIB202 from Edwardsiella

BMC Microbiology, 2017
Background Conjugation is a major type of horizontal transmission of genes that involves transfer of a plasmid into a recipient using specific conjugation machinery, which results in an extended spectrum of bacterial antibiotics resistance.
Yang Liu, Yanan Gao, Xiaohong Liu, Qin Liu, Yuanxing Zhang, Qiyao Wang, Jingfan Xiao   +6 more
doaj   +1 more source

Evaluation of an enclosed air-lift photobioreactor (ALPBR) for biomass and lipid biosynthesis of microalgal cells grown under fluid-induced shear stress

Biotechnology & Biotechnological Equipment, 2021
An enclosed air-lift photobioreactor (ALPBR) is considered an efficient lab-scale bioreactor for microalgae cell growth and lipid biosynthesis. However, fluid-induced shear stress and mixing are two main factors that affect physiological metabolism in ...
Ning Ding, Chao Li, Tao Wang, Meijin Guo, Ali Mohsin, Siliang Zhang   +5 more
doaj   +1 more source

FLOCCULATION BIOREACTORS [PDF]

, 2010
One of the main goals of bioprocess engineering is to increase the productivity of biotechnological processes and a vigorous progress has been observed in that field over the last decades. Fermentation based processes are not an exception and, in order to achieve those objectives, techniques such as the use of high cell density systems have been ...
Vicente, A. A., Mota, M., Teixeira, J. A.   +2 more
openaire   +2 more sources

Enhancing transglutaminase production of Streptomyces mobaraensis by iterative mutagenesis breeding with atmospheric and room-temperature plasma (ARTP)

Bioresources and Bioprocessing, 2017
Objectives To improve the fermentation production of transglutaminase (TGase) from Streptomyces mobaraensis for applications in the food industry, the atmospheric and room-temperature plasma (ARTP) mutagenesis was applied to breed S.
Ying Jiang, Yue-Peng Shang, Hao Li, Chao Zhang, Jiang Pan, Yun-Peng Bai, Chun-Xiu Li, Jian-He Xu   +7 more
doaj   +1 more source

Comprehensive reconstruction and evaluation of Pichia pastoris genome-scale metabolic model that accounts for 1243 ORFs

Bioresources and Bioprocessing, 2017
Background Pichia pastoris is one of the most important cell factories for production of industrial enzymes and heterogenous proteins. The genome-scale metabolic model of high quality is crucial for comprehensive understanding of the P.
Rui Ye, Mingzhi Huang, Hongzhong Lu, Jiangchao Qian, Weilu Lin, Ju Chu, Yingping Zhuang, Siliang Zhang   +7 more
doaj   +1 more source

Magnetic-driven dynamic culture promotes osteogenesis of mesenchymal stem cell

Bioresources and Bioprocessing, 2021
Effective nutrient transport and appropriate mechanical stimulation play important roles in production of tissue-engineered bone grafts. In this study, an experimental set-up for magnetic-driven dynamic culture of cells was designed to mimic the ...
Mengyang Hao, Minghao Xiong, Yangyang Liu, Wen-song Tan, Haibo Cai   +4 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Improved methanol-derived lovastatin production through enhancement of the biosynthetic pathway and intracellular lovastatin efflux in methylotrophic yeast

Bioresources and Bioprocessing, 2018
Background Methanol has attracted interest as a substrate for improvement of product titers and yields of bioprocesses, because methanol has a more reduced state than sugars do and can be renewably synthesized from abundant natural gas supplies.
Yiqi Liu, Chenxiao Bai, Qin Xu, Jiahui Yu, Xiangshan Zhou, Yuanxing Zhang, Menghao Cai   +6 more
doaj   +1 more source

Multi-omics analysis defines 5-fluorouracil drug resistance in 3D HeLa carcinoma cell model

Bioresources and Bioprocessing, 2021
Cervical cancer is a serious health problem in women around the globe. However, the use of clinical drug is seriously dampened by the development of drug resistance.
Lin Wang, Xueting Wang, Tong Wang, Yingping Zhuang, Guan Wang   +4 more
doaj   +1 more source

Enzyme‐Loaded Fe3+‐Modified Polydopamine Microparticles: Bioreactor Systems for Operating Biocatalytic Cascades, Enantioselective Transformations and Sensor Applications

Advanced Functional Materials, EarlyView.
Enzyme‐loaded Fe3+‐modified polydopamine microparticles (Fe3+‐PD) act as hybrid biocatalytic frameworks demonstrating NADH peroxidase‐mimic catalytic activities, operation of biocatalytic cascades in confined media, and enantioselective oxidation of D/L‐DOPA. ABSTRACT We report on the synthesis of Fe3+‐modified porous polydopamine microparticles acting
Liubing Kong, Sérgio R. S. Veloso, Yichen Han, Jianghe Zhao, Vitaly Gutkin, Ofir Tirosh, Itamar Willner   +6 more
wiley   +1 more source