Results 11 to 20 of about 96,256 (296)
Sustainable Fabrication of Tailored Bone Substitutes: From High-Throughput Scaffold Manufacturing, Scaled-Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor. [PDF]
Adv Sci (Weinh)ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Braun F +10 more
europepmc +2 more sources
Cyclic Mechanical Loading of Cardiomyocytes via Pressure-Driven Non-Planar Membrane Deformation in a Bioreactor System. [PDF]
Adv Sci (Weinh)In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Mansoor H +11 more
europepmc +2 more sources
Stem cell expansion and bioreactor development [PDF]
, 2010 PhDA major challenge to the clinical success of cell-based tissue engineering strategies is the ability to obtain sufficient numbers of cells within an acceptable time frame.
Ramlogan, Anil Shiva
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Cytotoxicity micropollutant removal in a crossflow membrane bioreactor [PDF]
, 2011 The application of membrane bioreactor (MBR) technology was investigated with the aim of evaluating its potential for cytostatic drug and cytotoxicity bioremoval. The toxicity removal was assessed from biomarker test. CP removal of up to 80% was achieved
Delgado, Luis Fernando +14 more
core +1 more source
Hierarchical Flux-Protection Engineering Stabilizes Oxidation-Prone Metabolic Nodes for High-Level Curcumin Biosynthesis. [PDF]
Adv Sci (Weinh)Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Chen J +10 more
europepmc +2 more sources
Bioresources and Bioprocessing, 2023 Because of its potent antioxidant effects, lycopene has been used in various industries including, but not limited to, food, medical, and cosmetic industries.
Zhen Luo +6 more
doaj +1 more source
Biological treatment and thickening with a hollow fibre membrane bioreactor [PDF]
, 2014 Aerobic operation of an immersed hollow fibre membrane bioreactor, treating municipal wastewater supplemented with molasses solution, has been studied across mixed liquor suspended solids (MLSS) concentrations between 8 and 32 g L-1, the higher ...
Connery, Karen A. +6 more
core +1 more source
Nature Communications, 2018 In humans, caspase-5 is an LPS sensor that can induce gasdermin D cleavage and pyroptosis. Here, the authors show that zebrafish caspy2 is a functional homolog as it also senses cytosolic LPS to activate the noncanonical inflammasome and to protect ...
Dahai Yang +13 more
doaj +1 more source
Biotechnology for Biofuels, 2019 Background Acetate, an economical industrial chemical, which is also the precursor of acetyl-CoA, could serve as an alternative substrate for biomanufacturing.
Qin Xu +9 more
doaj +1 more source
Design of a bubble-swarm bioreactor for animal cell culture [PDF]
, 1994 Gudermann F, Lütkemeyer D, Lehmann J. Design of a bubble-swarm bioreactor for animal cell culture. Cytotechnology. 1994;15(1-3):301-309.A stationary bubble-swarm has been used to aerate a mammalian cell culture bioreactor with an extremely low gas flow ...
Lehmann, Jürgen +2 more
core +1 more source