Results 31 to 40 of about 185,824 (352)

Iterative design of dynamic experiments in modeling for optimization of innovative bioprocesses [PDF]

, 2009
Finding optimal operating conditions fast with a scarce budget of experimental runs is a key problem to speed up the development and scaling up of innovative bioprocesses. In this paper, a novel iterative methodology for the model-based design of dynamic
Cristaldi, Mariano Daniel, Grau, Ricardo José Antonio, Martínez, Ernesto Carlos   +2 more
core   +1 more source

Mathematical modeling and numerical simulation of a bioreactor landfill using Feel++ [PDF]

, 2016
In this paper, we propose a mathematical model to describe the functioning of a bioreactor landfill, that is a waste management facility in which biodegradable waste is used to generate methane.
Dollé, Guillaume, Duran, Omar, Feyeux, Nelson, Frénod, Emmanuel, Giacomini, Matteo, Prud'homme, Christophe   +5 more
core   +5 more sources

Magnetic-driven dynamic culture promotes osteogenesis of mesenchymal stem cell

Bioresources and Bioprocessing, 2021
Effective nutrient transport and appropriate mechanical stimulation play important roles in production of tissue-engineered bone grafts. In this study, an experimental set-up for magnetic-driven dynamic culture of cells was designed to mimic the ...
Mengyang Hao, Minghao Xiong, Yangyang Liu, Wen-song Tan, Haibo Cai   +4 more
doaj   +1 more source

Computational fluid dynamic analysis of bioprinted self-supporting perfused tissue models [PDF]

, 2020
Natural tissues are incorporated with vasculature, which is further integrated with a cardiovascular system responsible for driving perfusion of nutrient‐rich oxygenated blood through the vasculature to support cell metabolism within most cell‐dense ...
Bonewald, Lynda F., Ekser, Burcin, Li, Ping, McCarthy, Brian Paul, Prideaux, Matthew, Sego, T. J., Smith, Lester Jeshua, Sterner, Jane, Tovar, Andres   +8 more
core   +1 more source

Transposon insertion sequencing reveals T4SS as the major genetic trait for conjugation transfer of multi-drug resistance pEIB202 from Edwardsiella

BMC Microbiology, 2017
Background Conjugation is a major type of horizontal transmission of genes that involves transfer of a plasmid into a recipient using specific conjugation machinery, which results in an extended spectrum of bacterial antibiotics resistance.
Yang Liu, Yanan Gao, Xiaohong Liu, Qin Liu, Yuanxing Zhang, Qiyao Wang, Jingfan Xiao   +6 more
doaj   +1 more source

Multi-omics analysis defines 5-fluorouracil drug resistance in 3D HeLa carcinoma cell model

Bioresources and Bioprocessing, 2021
Cervical cancer is a serious health problem in women around the globe. However, the use of clinical drug is seriously dampened by the development of drug resistance.
Lin Wang, Xueting Wang, Tong Wang, Yingping Zhuang, Guan Wang   +4 more
doaj   +1 more source

Improved methanol-derived lovastatin production through enhancement of the biosynthetic pathway and intracellular lovastatin efflux in methylotrophic yeast

Bioresources and Bioprocessing, 2018
Background Methanol has attracted interest as a substrate for improvement of product titers and yields of bioprocesses, because methanol has a more reduced state than sugars do and can be renewably synthesized from abundant natural gas supplies.
Yiqi Liu, Chenxiao Bai, Qin Xu, Jiahui Yu, Xiangshan Zhou, Yuanxing Zhang, Menghao Cai   +6 more
doaj   +1 more source

Airlift Bioreactors - Bioreactors Design

, 2011
Producción ...
Guieysse, Benoit, Quijano Govantes, Guillermo, Muñoz Torre, Raúl   +2 more
openaire   +3 more sources

Bio-reactor chamber [PDF]

, 1989
A bioreactor for cell culture is disclosed which provides for the introduction of fresh medium without excessive turbulent action. The fresh medium enters the bioreactor through a filter with a backwash action which prevents the cells from settling on ...
Chandler, Joseph A.
core   +1 more source

A miniaturized bioreactor system for the evaluation of cell interaction with designed substrates in perfusion culture [PDF]

, 2012
In tissue engineering, the chemical and topographical cues within three-dimensional (3D) scaffolds are normally tested using static cell cultures but applied directly to tissue cultures in perfusion bioreactors.
Anderson, Britland, Casey, Chen, Clark, Csaderova, Curtis, Curtis, Flemming, Gadegaard, Gadegaard, Gailit, Hubbell, Jelinek, Korin, Lakatos, Link, Lu, Massia, Mirastschijski, Mosmann, Noble, Robert, Salem, Seunarine, Stevens, Sun, Sun, Sørensen, Terai, Wojciak-Stothard, Zong   +31 more
core   +2 more sources