The <i>Sinorhizobium meliloti</i> chemoreceptor McpU mediates positive and negative chemotaxis responses to dipeptides and competes with periplasmic solute-binding proteins for ligand binding. [PDF]
Agyei FK, Dhiman N, Scharf BE.
europepmc +1 more source
Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao +2 more
wiley +1 more source
Computational Oncology of Chemotaxis-Driven Tumour-Immune Spatial Patterning and Stability. [PDF]
Liu Z +6 more
europepmc +1 more source
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao +10 more
wiley +1 more source
RAC2 orchestrates immune cell actin remodeling and migration. [PDF]
Berthiaume Fox KA +3 more
europepmc +1 more source
Evolution of Physical Intelligence Across Scales
By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu +7 more
wiley +1 more source
Chemotactic self-organization captures the dynamics of mammalian hair follicle patterning. [PDF]
Ibrahimi M +3 more
europepmc +1 more source
A Unifying Approach to Self‐Organizing Systems Interacting via Conservation Laws
The article develops a unified way to model and analyze self‐organizing systems whose interactions are constrained by conservation laws. It represents physical/biological/engineered networks as graphs and builds projection operators (from incidence/cycle structure) that enforce those constraints and decompose network variables into constrained versus ...
F. Barrows +7 more
wiley +1 more source
3D chemotaxis chip for investigating natural killer cell migration mechanisms. [PDF]
Temples MN +5 more
europepmc +1 more source
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley +1 more source

